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>Revistas >Medicina Crítica >Año 2011, No. 4


Carrillo-Esper R, Márquez AP, Sosa-García J, Aponte UM, Bobadilla AA, Briones GC, D´Ector LD, Elizondo AS, Gracia LR, Izaguirre AR, Lizárraga LS, López SN, Martínez ZR, Paredes AR, Pizaña DA, Ramírez RF, Ramírez ZL, Sánchez ZM, Vázquez GF, Villagómez OA, Zárate CP, Aldrete-Velasco J, Coronado AS, Jiménez GC, Cárdenas AA, Fonseca SL, Johnson HJ, Luque FD
Guía de práctica clínica para la tromboprofilaxis en la Unidad de Terapia Intensiva
Rev Asoc Mex Med Crit y Ter Int 2011; 25 (4)

Idioma: Español
Referencias bibliográficas: 122
Paginas: 227-254
Archivo PDF: 195.80 Kb.

[Texto completo - PDF]

RESUMEN

La enfermedad tromboembólica venosa es una de las principales complicaciones en los pacientes hospitalizados, comprende la trombosis venosa profunda (TVP) y el embolismo pulmonar (EP). Los enfermos hospitalizados presentan al menos un factor de riesgo para un evento tromboembólico venoso (ETV), de los cuales aproximadamente 40% presentan 3 o más factores de riesgo. Los pacientes con una enfermedad médica aguda tienen mayor riesgo de presentar un ETV y aproximadamente entre 10 a 30% de los pacientes con patología médica tiene TVP o desarrollan EP. Estudios clínicos actuales demuestran que los pacientes con patología médica presentan mayor riesgo de un ETV que los enfermos quirúrgicos.
La enfermedad tromboembólica venosa incrementa de manera significativa la morbilidad y mortalidad en los pacientes con enfermedades graves. En la Unidad de Terapia Intensiva (UTI) la ausencia de tromboprofilaxis contribuye a una incidencia de 13 a 31% de cuadros sintomáticos o asintomáticos de TVP en el enfermo en estado crítico.
Objetivos: La realización de esta guía de práctica clínica (GPC) tiene como finalidad homologar las prácticas de evaluación, detección y prevención de la enfermedad tromboembólica venosa en el enfermo adulto y pediátrico graves, con el objetivo de mejorar la calidad, atención y seguridad en esta población, teniendo como objetivo ser un marco de referencia para la toma de decisiones clínicas con base en las recomendaciones sustentadas en la mejor evidencia disponible en la actualidad.
Usuarios: Esta guía de práctica clínica está dirigida a médicos intensivistas, internistas, urgenciólogos, pediatras, neonatólogos y a todos aquellos involucrados en el manejo del paciente críticamente enfermo con riesgo de un evento tromboembólico en la unidad de terapia intensiva.


Palabras clave: Enfermedad tromboembólica venosa, tromboprofilaxis, tromboprofilaxis en pediatría, profilaxis, tromboembolia pulmonar, trombosis venosa profunda.


REFERENCIAS

  1. Torbicki A, Perrier A, Konstantinides S, Agnelli G, Galie N, Pruszczyk P, et al. Guidelines on the diagnosis and management of acute pulmonary embolism. European Heart Journal 2008;29:2276–2315.

  2. Heit JA. The epidemiology of venous thromboembolism in the community: Implications for prevention and management. J Thromb Thrombolysis 2006;21:23–29.

  3. Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, et al. Prevention of venous thrombo-embolism: American College of Chest Physicians. Evidence- based clinical practice guidelines (8th edition). Chest 2008;133:381–453.

  4. Geerts W, Selby R. Prevention of venous thromboembolism in the ICU. Chest 2003;124:357–363.

  5. Moser KM, Fedullo PF, Littejohn JK, Crawford R. Frequent asymptomatic pulmonary embolism in patients with deep venous thrombosis. JAMA 1994;271:223–225.

  6. Dalen JE. Pulmonary embolism: what have we learned since Virchow? Natural history, pathophysiology, and diagnosis. Chest 2002;122:1440–1456.

  7. Kearon C. Natural history of venous thromboembolism. Circulation 2003;107:22–30.

  8. Sandler DA, Martin JF. Autopsy proven pulmonary embolism in hospital patients: are we detecting enough deep vein thrombosis? J R Soc Med 1989;82:203-205.

  9. Murin S, Romano PS, White RH. Comparison of outcomes after hospitalization for deep venous thrombosis or pulmonary embolism. Thromb Haemost 2002;88:407–414.

  10. Stein PD, Kayali F, Olson RE. Estimated case fatality rate of pulmonary embolism, 1979 to 1998. Am J Cardiol 2004;93:1197–1199.

  11. Stein PD, Beemath A, Olson RE. Trends in the incidence of pulmonary embolism and deep venous thrombosis in hospitalized patients. Am J Cardiol 2005;95:1525–1526.

  12. Dalen JE, Alpert JS. Natural history of pulmonary embolism. Prog Cardiovasc Dis 1975;17:259–270.

  13. Nordstrom M, Lindblad B. Autopsy-verified venous thromboembolism within a defined urban population the city of Malmo, Sweden. APMIS 1998;106:378–384.

  14. Oger E. Incidence of venous thromboembolism: a community-based study in Western France. EPI-GETBP Study Group. Grouped’Etude de la Thrombose de Bretagne Occidentale. Thromb Haemost 2000;83:657–660.

  15. Neuhaus A, Bentz RR, Weg JG. Pulmonary embolism in respiratory failure. Chest 1978;73:460–465.

  16. Moser KM, LeMoine JR, Nachtwey FJ, Spragg RG. Deep venous thrombosis and pulmonary embolism: Frequency in a respiratory intensive care unit. JAMA 1981;246:1422–1424.

  17. Cullen DJ, Nemeskal AR. The autopsy incidence of acute pulmonary embolism in critically ill surgical patients. Intensive Care Med 1986;12:399–403.

  18. Blosser SA, Zimmerman HE, Stauffer JL. Do autopsies of critically ill patients reveal important findings that were clinically undetected? Crit Care Med 1998;26:1332–1336.

  19. Sigler L, Romero T, Meillón LA, Gutiérrez L, Aguirre GJ, Esparza C. Tromboembolia pulmonar en un periodo de 10 años. Rev Med IMSS 1996;34:7-11.

  20. Sandoval ZJ, Martínez GML, Gómez A, Palomar A, Pulido T, Zevallos M. PAC Cardio-1. Tromboembolia pulmonar aguda. Sociedad Mexicana de Cardiología 1998:7-9.

  21. Samama MM, Cohen AT, Darmon JY, Desjardins L Eldor A, Janbon C, et al. A comparison of enoxaparin with placebo for the prevention of venous thromboembolism in acutely ill medical patients. Prophylaxis in Medical Patients with Enoxaparin Study Group. N Engl J Med 1999;11:793–800.

  22. “Adapte. Guideline adaptation: Enhancing efficiency in guideline development and utilization.” Disponible en: http://www.adapte.org/www/upload/manual_and_tools/4PAdapte_validated.pdf

  23. Hirsh J, Guyatt G, Albers G, Harrington R, Schunemann H. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines: Antithrombotic and Thrombolytic Therapy 8th ED. Chest 2008;133:71S-105S.

  24. National Health and Medical Research Council. Clinical practice guideline for the prevention of venous thromboembolism (deep vein thrombosis and pulmonary embolism) in patients admitted to Australian hospitals. Melbourne: National Health and Medical Research Council; 2009.

  25. Otero CR, Grau SE, Jiménez CD, Uresandi RF, López VJ, Calderón SE, et al. Prophylaxis of Venous Thromboembolism. Arch Bronconeumol 2008;44(3):160-169.

  26. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, et al. Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008;36:296-327.

  27. Carrillo ER, Sosa GJ, Ramírez ZL. Desarrollo e implementación de procesos para incrementar la seguridad de atención en la unidad de terapia intensiva de la Fundación Clínica Médica Sur. Rev Invest Med Sur Mex 2010;17(4):172-185.

  28. Weiner BJ, Alexander JA, Shortell SM, Baker LC, Becker M, Geppert JJ. Quality improvement implementation and hospital performance on quality indicators. Health Serv Res 2006;41:307-334.

  29. Martín MC, Cabré LI, Ruiz J, Blanch LI, Blanco J, Castillo F, et al. Indicadores de calidad en el enfermo crítico. Med Intensiva 2008;32(1):23-32.

  30. Wells PS, Anderson DR, Rodger M, Ginsberg JS, Kearon C, Gent M, et al. Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost 2000;83:416–420.

  31. Le Gal G, Righini M, Roy PM, Sanchez O, Aujesky D, Bounameaux H, et al. Prediction of pulmonary embolism in the emergency department: the revised Geneva score. Ann Intern Med 2006; 144:165–171

  32. Caprini JA. Thrombosis risk assessment as a guide to quality patient care. Dis Mon 2005;51:70-78.

  33. Cook DJ, Crowther MA. Thromboprophylaxis in the intensive care unit: Focus on medical-surgical patients. Crit Care Med 2010;38:76–82.

  34. Cade JF. High risk of the critically ill for venous thromboembolism. Crit Care Med 1982;10:448–450.

  35. Fraisse F, Holzapfel L, Couland JM, Simonneau G, Bedock B, Feissel M, et al. Nadroparin in the prevention of deep vein thrombosis in acute decompensated COPD. The Association of Non-University Affiliated Intensive Care Specialist Physicians of France. Am J Respir Crit Care Med 2000;161:1109-1114.

  36. James AH, Abel DE, Brancazio LR. Anticogulants in Pregnancy. Obstetrical and Gynecological Survey 2005;61:59-69.

  37. Gibson PS, Powrie R. Anticoagulants and pregnancy: When are they safe? Cleveland Clinic Journal of Medicine 2009;76:113-127.

  38. Senzolo M, Sartori MT, Lisman T. Should we give thromboprophylaxis to patients with liver cirrhosis and coagulopathy? HPB 2009;11:459-464.

  39. National Institute for Health and Clinical Excellence. Reducing the risk of venous thromboembolism (deep vein thrombosis and pulmonary embolism) in patients admitted to hospital, 2010.

  40. Monagle P, Michelson AD, Bovill E, et al. Antithrombotic therapy in children. Chest 2001;119(S):344S-370S.

  41. Ignjatovic V, Furmedge J, Newall F, et al. Age related differences in heparin response. Thromb Res 2006;118:741-745.

  42. Martínez C. Empleo de anticoagulantes. En: Enfermedad tromboembólica venosa. Martínez C. Editorial Alfil. México, DF. 2007:82-94.

  43. Ignjatovic V, Summerhayes R, Than J. Therapeutic range for unfractionated heparin therapy: age related differences in response in children. J Thromb Haemostatic 2006;4:2280-2282.

  44. Ignjatovic V, Summerhayes R, Gan A. Monitoring unfractionated heparin therapy: which anti-factor Xa assay is appropriate? Thromb Res 2007;120:347-351.

  45. Majeurus P, Tollefsen D. Coagulación sanguínea y anticoagulantes, trombolíticos y antiplaquetarios. En: Goodman & Gilman. Las bases farmacológicas de la terapéutica. Brunton L, Lazo J, Parker K (editors). McGrawHill, 11° edición. USA, 2006.

  46. Dix D, Andrew M, Marzinotto V. The use of low molecular weight heparin in pediatric patients: a prospective cohort study. J Pediatr 2000;136:439-445.

  47. Massicotte MP, Adams M, Leaker M. A normogram establish therapeutic levels of low molecular weight heparin, clivarine in children requiring treatment for venous thromboembolism (VTE). Thromb Haemost 1997;78(suppl):282-286.

  48. Monagle P, Barnes C. Ignjatovic V. Developmental haemostatic; impact of the clinical haemostatic laboratories Thromb Res 2006;95:362-372.

  49. Andrew M, Vegh P, Johnston M. Maduration hemostatic system during childhood. Blood 1992;80:1998-2005.

  50. Andrew M, Paes B, Johnston M. Development of hemostatic system in the neonate and young infant. Am J Pediatr Hematol Oncol 1990;12:95-104.

  51. Andreus M, Schmidt B, Mitchell L. Thrombin generation in newborn plasma is critically dependent on the concentration of prothrombin. Thromb Haemostatic 1990;63:27-30.

  52. Andreus M, Mitchell L. Vegh P. Thrombin regulation in children differs from adults in the absence and presence of heparin. Thromb Haemostatic 1994;72:836-842.

  53. Michelson AD, Bovill E. Andrew M. Anti-thrombotic therapy in children. Chest 1995;108(suppl):506S-522S.

  54. Hirsch J. Warkentin TE, Raschke R. Heparin and low molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy and safety. Chest 1998;114(suppl):489S-510S.

  55. Massicotte MP, Julian JA, Gent M. An open-label randomized controlled trial of low molecular weight heparin for the prevention of central venous line-related thrombotic complications in children: the PROTEKT trial. Thromb Res 2003;109:85-92.

  56. Hirsch J. Heparin, Drug Therapy. N Engl J Med 1991;324:1565-1574.

  57. Fernández-Pavón A, Álvarez Rojas E. Terapia antitrombótica. En: Cuidados Intensivos Pediátricos. Ruza F (editor). Ediciones Norma Capitel. 3° Edición pp1482-1484

  58. Andrew Marzinotto V, Massicotte P. Heparin therapy in pediatric patients: a prospective cohort study. Pediatric Res 1994;35:78-83.

  59. Raschke RA, Reilly BM, Guidry JR. The weight based heparin doses nomogram compared with a “standard care“ nomogram: a randomized controlled trial. Ann Intern Med 1993;119:874-881.

  60. Taketomo C, Hodding J, Kraus D. Manual de prescripción pediátrica. Lexicom, 15° edición. USA 2008:617-619.

  61. Parker R, Hazelzet J. Coagulation issues in the PICU. En: Roger´s Textbook of Pediatric Intensive Care. Nichols D (editor). Lippincott Williams & Wilkins. USA 2008, chapter 103. (versión electrónica).

  62. Cruickshank MK, Levine MN, Hirsh J. A standard heparin nomogram for the management of heparin therapy. Arch Intern Med 1991; 151:333-337.

  63. Kuhle S, Eulmesekian P, Kavanagh B. A clinically significant incidence of bleeding in critically ill children receiving therapeutic doses of unfractionated heparin: a prospective cohort study. Haematologica 2007;92:244- 247.

  64. Murphy MS, John PR, Mayer AD. Heparin Therapy and bone fractures. Lancet 1992;340:1098.

  65. Monagle P, Chalmers E, Chan A, deVeber G, Kirkham F, Massicotte P, Michelson A. Antithrombotic Therapy in Neonates and Children. American College of Chest Physicians Evidence-Based Clinical Practice: Guidelines (8th Edition). Chest 2008;133;887S-968S.

  66. Severin T, Sutor AH. Heparin induced thrombocitopenia in pediatrics. Semin Thromb Hemost 2001;27:293-299.

  67. Potter C, Gill JC, Scott JP. Heparin induced thrombocytopenia in a child. J Pediatr 1992;121:135-138.

  68. Schummet M, Risch L, Huber AR. Heparin induced thrombocytopenia-associated thrombosis in pediatric intensive care patients. Pediatrics 2002;109:E10.

  69. Boshkov L, Ibsen L, Kirby A. Heparin induced thrombocytopenia in neonates and very young children undergoing congenital cardiac surgery. J Thromb Haemost 2003;1(suppl 1);1494.

  70. Etches W, Stang L, Conradi A. Incidence of heparin induced thrombocytopenia in a pediatric intensive care population. Blood 2003;102(suppl):536a.

  71. Risch L, Fischer JE, Herklotz R. Heparin induced thrombocytopenia in paediatrics: clinical characteristics therapy and outcomes. Intensive Care Med 2004;30:1615-1624.

  72. Massicotte MP, Julian A, Gent M. An open-label randomized controlled trial of low molecular weight heparin compared to Heparin and Coumadin for the treatment of venous trombembolic events in children: The REVIVE trial. Thromb Res 2003;109:85-92.

  73. Blanchette V, Chan A, Dror Y. Thrombosis and embolism. En: Avery’s Neonatology. Mac Donald,M, Seshia M. Mullett M (editors) Lippicott Williams & Wilkins, 6° edition 2005 pp1217-1234.

  74. Andrew M, David M, Adams M. Venous thromboembolic complications in children: First analyses of the Canadian registry of VTE. Blood 1994;83:1251-7.

  75. Trottier SJ, Veremakis C, O’Brien J. Femoral deep vein thrombosis associate with central venous catheterization: results from a prospective randomized trial. Crit Care Med 1995;23:52-59.

  76. Canizo F, Cassalett G. Monitoreo hemodinámico en pediatría. En: Cuidado intensivo Pediátrico y neonatal. Forero J, Alarcón J y Cassalett G. Distribuna 2° edición, Colombia, 2007 pp 38-39.

  77. Andrew M, Marzinotto V, Penchardz P. A cross sectional study of catheter related thrombosis in children receiving total parenteral nutrition at home. J Pediatr 1995;126:358-363.

  78. Moukarzel A, Haddad I, Ament ME. 230 patients years of experience with home long-term parenteral nutrition in childhood: natural history and life of central venous catheter. J Pediatr Surg 1994;29:1323-7.

  79. Krafte-Jacobs B, Sibit CJ, Mejía R. Catheter related thombosis in criticall ill children: comparison of catheter with or without heparin bonding. J Pediatr 1995;126:50-4.

  80. Kamala F, Boo NY, Cheah FC. Randomized controll trial of heparin for prevention of blockage of peripherally inserted central catheters in neonates. Acta Paediatr 2002;91:1350-6.

  81. Groh-wargo S, Thompson M, Cox J. Nutritional Care for high risk newborn. Revised, 3° edition, Chicago IL Precept press, inc 2002.

  82. Nieman Carney L, Nepa A, Shubin Cohen S. Parenteral and Enteral Nutrition Support: Determining the best way to feed. In: ASPEN Pediatric Nutrition Support Core Curriculum. Corkins M (editor). ASPEN. USA, 2010:433-447.

  83. Silverds KM, Darlow BA, Winterbourn CC. Pharmacologic levels of heparin do not destabilize neonatal parenteral nutrition. J Parenter Enteral Nutr 1998;22:311-314.

  84. Fuster V, Rydén LE, Cannom DS, Crijns HJ, Curtis AB, Ellenbogen KA, et al. ACC/AHA/ESC: Guía de Práctica Clínica 2006 para el manejo de pacientes con fibrilación auricular. Rev Esp Cardiol 2006;59(12):1329.e1-64.

  85. Tachil J, Gatt A, Martlew V. Managment of surgical patients receiving anticoagulation and antiplatelet agents. Br J Surgery 2008;95:1937-1448.

  86. Kannankeril P, Fish F. Disorders of cardiact rhythm and conduction. En: Moss and Adams. Heart disease in infants children and adolescents including the fetus and young adults. Allen H, Driscoll D, Shaddy R (editors). Lippincott Williams & Wilkins. USA 2008. Chapter 14.

  87. Singer DE, Albers GW, Dalen JE. Anti-thrombotic therapy in atrial fibrillation: American College of Chest Physicians evidence base clinical practice guidelines (8° edición). Chest 2008;133(6 suppl):546S-592S.

  88. Ruza F, Pérez J. Cuidados posoperatorios inmediatos. En: Tratado de Cuidados Intensivos Pediátricos. Ruza F (editor). Ediciones Norma Capitel. 3° edición Madrid, España 2003;I:435-446.

  89. Monagle P, Cochrane A, McCrindle B. Thromboembolic complications after Fontan procedures: the role of prophylactic anticoagulation. J Thorac Cardiovasc Surg 1998;115:493-498.

  90. Marino B, Spray T, Greelei W. Separating the circulation: cavo-pulmonary connections (bidirectional Gleen, hemi-fontan) and the modify Fontan operation. En: Critical Care disease in infants and children. Nichols D (editor). Elsevier Mosby. USA 2006 chapter 41.

  91. Kaulis R, Ziemer G, Rauch R. prophylaxis of thromboembolic complications after the Fontan operations( total cavo-pulmonary anastomosis). J Thorac Cardiovasc Surg 2005;129:569-575.

  92. Seipelt RG, Franke A, Vazquez Jimenez JF. Thromboembolic complication after Fontan procedures: Comparison of different therapeutic approaches. Ann Thorac Surg 2002;74:556-562.

  93. Hutter D, Redington A. The principles of management, and outcomes for patients with functionally univentricular hearts. In: Paediatric Cardiology. Anderson R, Baker E. Penny D, Redington A, Rigby M, Wernovsky G. 3era Edición. Editorial Churchill Livingstone Elsevier. 2010:687-696.

  94. Ricard Cervera, Jean-Charles Piette, Josep Font. El síndrome antifosfolípido: Las manifestaciones clínicas e inmunológicas y los patrones de expresión de la enfermedad en una cohorte de 1,000 pacientes. Arthritis and rheumatism 1990;33(8):1065-67.

  95. Berkun Y, Padeh S, Barash J, et al. Síndrome antifosfolípido y trombosis recurrente en los niños. Arthritis Care Research 2006;55(6):833-93.

  96. de Groot PG, Ronald HWM. Derksen Antiphospholipid antibodies: update on detection, pathophysiology, and treatment. Curr Op Hematology 2004;11:165–169.

  97. Scottish Intercollegiate Guidelines Network. Prevention and management of venous thromboembolis: A national clinical guideline. Part of NHS Quality Improvement Scotland 2010:1-87.

  98. Anton Heinz Sutor, Anthony K.C. Chan, and Patricia Massicotte. Low-Molecular-Weight Heparin in Pediatric Patients. Sem Thrombosis Hemostasis 2004;30Supplement1:31-9.

  99. Bernd Jilma, Sridhar Kamath, Gregory Y H Lip. ABC of antithrombotic therapy Antithrombotic therapy in special circumstances. II–In children, thrombophilia, and miscellaneous conditions. BMJ 2003;326:93-6.

  100. Baglin TP, Keeling DM, Watson HG. Guidelines on oral anticoagulation (warfarin): third edition –2005 update. British Society for Haematology 2005;132:277–285.

  101. Bajzar L, K. Chan Anthony, Massicotte MP, Michell LG, Thrombosis in children with malignancy. Curr Opin Pediatr 2006;1:1-9.

  102. Lipay NV, Dmitriev VV, Borisenok MB. Thrombotic complications during cancer treatment in children. Experimental oncology 2007;29:231-235.

  103. Elhasid R, Lanir N, Sharon R, et al, Propylactic therapy with enoxaparin during L-asparaginase treatment in children with acute lymphoblastic leukemia. Blood Coagul Fibrinolysis 2001;12:367-370.

  104. Petersen L. Anticoagulation therapy for prevention and treatment of venous thromboembolic events in cancer patients: A review of current guidelines. Cancer Treatmente Reviews 2009;35:754-764.

  105. Mitchell MG, Andrew M, Hanna K. A prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with Lasparginase (PARKA study). Cancer 2003;97:508-516.

  106. Ruud D, Holmstrom H, De Lange C. Low dose warfarin for the prevention of central line-associated thromboses in children with malignancies: a randomized controlled study. Acta Paediatr 2006;95:1053-1059.

  107. Nowak-Gottl U, Munchow N, Klippel U. The course of fibrinolytic proteins in children with malignant bone tumours. Eur J Pediatr 1999;158(suppl 3):S151-S153.

  108. Deitcher SR. Cancer-related deep venous thrombosis: clinical importance, treatment challenges and management strategies. Sem Thrombosis and Hemostasis 2003;29:247-258.

  109. Wu C, Lee AY. Malignancy and venous thrombosis in the crital care patient. Crit Care Med 2010;38:2s,s64-s70.

  110. Mandal M, Falanga A, Piccioli A, Prandoni P. Venous thromboembolism and cancer: guidelines of Italian Association of Medical Oncology (AIOM). Critical Reviews in Oncology Hematology 2006;59:194-204.

  111. Lyman G, Khorana A, Falanga A, et al. American Society of clinical oncology guideline: recommendations for venous thromboembolism propylaxis and treatment in patients with cancer. J Clinical Oncology 2007;25:5590-5505.

  112. Wahl WL, Brandt MM, Ahrns KS, Zajkowski PJ, et al. Venous thrombosis incidence in burns patients preliminary results of a prospective study. J Burn Care Rehabil 2002;23;97-102.

  113. Ferguson RE, Critchfield A, Le Claire A, et al. Current practice thromboprofilaxis in the burn population. Burns 2005;31;964-966.

  114. Lawrence C, Atac B. Hematologic changes u masive burn injury. Crit Care Med 1992;2:1284-8.

  115. Garcia-Avello, Lorente JA, Perez CJ. Degree of hypercoagulability and hiperfybrinolisis is related to organ failure and prognosis after burn trauma. Tromb Res 1998;89:259-64.

  116. Yankah AC, Alexi-Meskhishvili V, Weng Y, et al. Performance of aortic and pulmonary homografts in the right ventricular outflow tract in children. J Heart Valve Dis 1995;4:392–395.

  117. Caldarone CA, Raghuveer G, Hills CB, et al. Long-term survival after mitral valve replacement in children aged 5 years: a multi-institutional study. Circulation 2001;104:I143–I147.

  118. Kadoba K, Jonas RA, Mayer JE, et al. Mitral valve replacement in the first year of life. J Thorac Cardiovasc Surg 1990;100:762–768.

  119. Milano A, Vouhe PR, Baillot-Vernant F, et al. Late results after left-sided cardiac valve replacement in children. J Thorac Cardiovasc Surg 1986;92:218–225.

  120. Spevak PJ, Freed MD, Castaneda AR, et al. Valve replacement in children less than 5 years of age. J Am Coll Cardiol 1986;8:901–908.

  121. Weinstein GS, Mavroudis C, Ebert PA. Preliminary experience with aspirin for anticoagulation in children with prosthetic cardiac valves. Ann Thorac Surg 1982;33:549–553.

  122. Schmidt B, Andrew M. Neonatal thrombosis: report of a prospective Canadian and international registry. Pediatrics 1995;96:939–943.



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