2014, Number 3
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Med Int Mex 2014; 30 (3)
Neurodegenerative Diseases: an Unavoidable Consequence of Aging?
García S, Villagómez-Ortiz AJ
Language: Spanish
References: 9
Page: 309-311
PDF size: 382.53 Kb.
ABSTRACT
This is a brief overview –from authors’ perspective– about the phenomena
involved in the brain aging process, the differences by sex of the
person who is aging, its association to the neurodegenerative diseases
and the great expectations that have created the diverse research groups
in this regard to identify early on the people that will suffer such catastrophe,
and implement effective measures of prophylaxis and/or treatment.
REFERENCES
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Mrak RE, Griffin ST, Graham DI. Aging-associated changes in human brain. J Neuropathol Exp Neurol 1997;56:1269- 1275.
Mahncke HW, Bronstone A, Merzenich MM. Brain plasticity and functional losses in the aged: scientific bases for a novel intervention. Prog Brain Res 2006;157:81-109.
Gouras GK. Convergence of synapses, endosomes, and prions in the biology of neurodegenerative diseases. Int J Cell Biol 2013;2013:141083. Epub 2013 Nov 7.
Johansson BB. Brain plasticity in health and disease. Keio J Med 2004;53:231-246.
Holmes BB, Diamond MI. Cellular mechanisms of protein aggregate propagation. Curr Opin Neurol 2012;25:721-726.
Frost B, Diamond MI. Prion-like mechanisms in neurodegenerative diseases. Nat Rev Neurosci 2010;11:155-159.
Stefanacci RG. The costs of Alzheimer's disease and the value of effective therapies. Am J Manag Care 2011;17:356- 362.