medigraphic.com
ISSN 0210-5187 (Electronic)

2014, Number 4-6

<< Back Next >>

Med Cutan Iber Lat Am 2014; 42 (4-6)

Calciphylaxis: a case series of 8 patients

Posada C, Feal C, Abalde M, Flórez Á, de la Torre C

Language: Spanish
References: 11
Page: 91-96
PDF size: 346.01 Kb.


ABSTRACT

Calciphylaxis is a life-threatening form of metastatic calcification-induced micro vascular occlusion syndrome. Although traditionally observed in patients with end-stage renal disease and secondary hyperparathyroidism (traditional patients), this condition is becoming increasingly reported in patients with normal renal and parathyroid function (non-traditional patients). Pathogenesis is poorly understood but it is thought to be multifactorial. There are no evidence-based medicine treatment options available for this disease. We report a cases series of eight patients, including traditional and non-traditional, suffering from calciphylaxis, who were diagnosed in our department between years 2001 and 2011. We compared the clinical and biologic characteristics of our patients, the treatment administered and their outcome with the data described in the literature.


REFERENCES

  1. Weenig RH, Sewell LD, Davis MD, McCarthy JT, Pittelkow MR. Calciphylaxis: natural history, risk factor analysis, and outcome. J Am Acad Dermatol. 2007; 56: 569-79.

  2. Kalajian AH, Malhotra PS, Callen JP, Parker LP. Calciphylaxis with normal renal and parathyroid function: not as rare as previously believed. Arch Dermatol. 2009; 145: 451-8.

  3. Nigwekar SU, Wolf M, Sterns RH, Hix JK. Calciphylaxis from nonuremic causes: a systematic review. Clin J Am Soc Nephrol. 2008; 3: 1139-43.

  4. Ng AT, Peng DH. Calciphylaxis. Dermatol Ther. 2011; 24: 256-62.

  5. Daudén E, Oñate MJ. Calciphylaxis. Dermatol Clin. 2008; 26: 557-68.

  6. Brandenburg VM, Cozzolino M, Ketteler M. Calciphylaxis: a still unmet challenge. J Nephrol. 2011; 24: 142-8.

  7. Harris RJ, Cropley TG. Possible role of hypercoagulability in calciphylaxis: review of the literature. J Am Acad Dermatol. 2011; 64: 405-12.

  8. Ross EA. Evolution of treatment strategies for calciphylaxis. Am J Nephrol. 2011; 34: 460-7.

  9. Raymond CB, Wazny LD, Sood AR. Sodium thiosulfate, bisphosphonates, and cinacalcet for calciphylaxis. CANNT J. 2009; 19: 25-7.

  10. Noureddine L, Landis M, Patel N, Moe SM. Efficacy of sodium thiosulfate for the treatment for calciphylaxis. Clin Nephrol. 2011; 75: 485-90.

  11. Basile C, Montanaro A, Masi M, Pati G, De Maio P, Gismondi A. Hyperbaric oxygen therapy for calcific uremic artriolopathy: a case series. J Nephrol. 2002; 15: 676-80.




2020     |     www.medigraphic.com