Sojo PJR, Vargas ÁAJ, Tinoco CV

Idioma: Español
Referencias bibliográficas: 15
Paginas:
Archivo PDF: 166.30 Kb.

RESUMEN

La cardiotoxicidad comprende todo un campo de estudio dentro de la disciplina de cardio oncología. A su vez, la radioterapia representa uno de los tratamientos más señalados en el desarrollo de cardiopatía asociada a terapias oncológicas; y en este caso en particular, se denomina Enfermedad Cardiaca Inducida por Radiación (ECIR).
La prevención, detección temprana, y el tratamiento de la ECIR, se mantienen en constante estudio y representan un desafío para el futuro, sabiendo que la sobrevida de pacientes con cáncer se mantiene en aumento, y por ende es probable que aumente la prevalencia de casos con complicaciones cardiacas asociadas a radiación.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Taylor C, Correa C, Duane FK, et al. Estimating the risks of breast cancer radiotherapy: evidence from modern radiation doses to the lungs and heart and from previous randomized trials. J Clin Oncol. 2017; 35:1641e1649.

2. Dess RT, Sun Y, Matuszak MM, et al. Cardiac events after radiation therapy: combined analysis of prospective multicenter trials for locally advanced non-small-cell lung cancer. J Clin Oncol. 2017; 35:1395e1402.

3. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2017. CA Cancer J Clin. 2017; 67:7–30. https://doi.org/10. 3322/caac.21387.

4. L. Beaton et al. / Clinical and Translational Radiation Oncology 19 (2019) 39–45. Doi: 10.1016/j.ctro.2019.08.001

5. Lewis GD, Farach A. Cardiovascular Toxicities of Radiation Therapy. Methodist Debakey Cardiovasc J. 2019; 15 (4): 274–281. https://doi.org/10.14797/mdcj-15-4-274

6. Da Silva, R.M.F.L. Effects of Radiotherapy in Coronary Artery Disease. Curr Atheroscler. Rep 21, 50 (2019). https://doi.org/10.1007/s11883-019-0810-x.

7. Qian Zhu. Cardiotoxicity associated with radiotherapy in breast cancer: a question-based review with current literatures. Cancer Treatment Reviews. Volume 68, July 2018. Pages 9-15. https://doi.org/10.1016/j.ctrv.2018.03.008.

8. Cuomo JR, Sharma GK, Conger PD, Weintraub NL. Novel concepts in radiation-induced cardiovascular disease. World J Cardiol. 2016; 8 (9): 504–519. https://doi.org/10.4330/wjc.v8.i9.504

9. Syed Wamique Yusuf. Radiation-Induced Cardiovascular Disease: a Clinical perspective. Front. Cardiovasc. Med. 26 October 2017. https://doi.org/10.3389/fcvm.2017.0006.

10. Lawrence B Marks. Cardiotoxicity of radiation therapy for Hodgkin lymphoma and pediatric malignancies. Up to date. Literature review current through Nov 2019.

11. Eoin Donnellan MD. Radiation-induced heart disease: A practical guide to diagnosis and management. Cleveland Clinic Journal of Medicine December 2016, 83 (12) 914-922; https://doi.org/10.3949/ccjm.83a.15104

12. Reed GW, Masri A, Griffin BP, Kapadia SR, Ellis SG, Desai MY. Long-term mortality in patients with radiation-associated coronary artery disease treated with percutaneous coronary intervention. Circ Cardiovasc Interv. 2016;9. https://doi.org/10.1161/CIRCINTERVENTIONS.115.003483

13. van Nimwegen FA, Schaapveld M, Cutter DJ, et al. Radiation dose -response relationship for risk of coronary heart disease in survivors of Hodgkin lymphoma. J Clin Oncol 2016; 34:235–243

14. Donnellan E, Krishnaswamy A, Hutt-Centero E, et al. Outcomes of patients with mediastinal radiationassociated severe aortic stenosis undergoing transcatheter aortic valve replacement. Circulation. 2018;138:1752–4. https://doi.org/10.1161/CIRCULATIONAHA.118.035514

15. L.F. Nhola, H.R. Villarraga / Rev Esp Cardiol. 2017; 70(7) :583–589; https://doi.org/10.1016/j.recesp.2017.01.0