medigraphic.com
Revista Médica Sinergia

2022, Número 02

<< Anterior

Revista Médica Sinergia 2022; 7 (02)


Síndrome de Lemièrre por Fusobacterium nucleatum: a propósito de un caso

Méndez RED, Chacón APP, Quesada SS

Idioma: Español
Referencias bibliográficas: 21
Paginas:
Archivo PDF: 199.36 Kb.


RESUMEN

El síndrome de Lemièrre es una patología poco frecuente, potencialmente mortal, que se produce por la trombosis venosa que envuelve la vena yugular interna posterior a la infección de vías respiratorias superiores por microorganismos anaerobios gram negativos. La inflamación producida puede provocar émbolos sépticos en otros órganos, como pulmones, tejidos blandos, bazo, hígado y cerebro. Esta condición fue llamada previamente “la enfermedad olvidada” debido a su rareza y a la poca familiaridad de los médicos con la misma. En este artículo se presenta el caso de una paciente femenina de 18 años, sana, en quien posterior a un cuadro agudo de faringoamigdalitis se documenta bacteremia por Fusobacterium nucleatum asociado a trombosis de la vena yugular izquierda y múltiples embolismos sépticos pulmonares.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Picture C, Bernard C, The B. Addresses articles. 1936.

  2. Álvarez Mavarez JD, Rodríguez López J, Álvarez Navascues F, Villanueva Montes MÁ. Enfermedad de Lemierre, a propósito de un caso. Rev am med respir. 2018;18(4):245–9.

  3. Campo F, Fusconi M, Ciotti M, Diso D, Greco A, Cattaneo CG, et al. Antibiotic and Anticoagulation Therapy in Lemierre’s Syndrome: Case Report and Review. J Chemother [Internet]. 2019;31(1):42–8. Available from: https://doi.org/10.1080/1120009X.2018.1554992

  4. Gore MR. Lemierre Syndrome : A Meta-analysis. 2020.

  5. Afra K, Laupland K, Leal J, Lloyd T, Gregson D. Incidence, risk factors, and outcomes of Fusobacterium species bacteremia. BMC Infect Dis. 2013;13(1).

  6. Laurencet ME, Rosset Zufferey S, Schrenzel J. Atypical presentation of Lemierre’s syndrome: Case report and literature review. BMC Infect Dis. 2019;19(1):1–4.

  7. Valerio L, Corsi G, Sebastian T, Barco S. Lemierre syndrome: Current evidence and rationale of the Bacteria-Associated Thrombosis, Thrombophlebitis and LEmierre syndrome (BATTLE) registry. Thromb Res [Internet]. 2020;196(September):494–9. Available from: https://doi.org/10.1016/j.thromres.2020.10.002

  8. Osowicki J, Kapur S, Phuong LK, Dobson S. The long shadow of Lemierre’s syndrome. J Infect [Internet]. 2017;74:S47–53. Available from: http://dx.doi.org/10.1016/S0163-4453(17)30191-3

  9. Raggio BS, Grant MC, Rodriguez K, Cripe PJ. Neonatal Lemierre Syndrome: Youngest Reported Case and Literature Review. Clin Pediatr (Phila). 2018;57(3):294–9.

  10. Sacco C, Zane F, Granziera S, Holm K, Creemers-Schild D, Hotz MA, et al. Lemierre Syndrome: Clinical Update and Protocol for a Systematic Review and Individual Patient Data Meta-analysis. Hamostaseologie. 2019;39(1):76–86.

  11. De Smet K, Claus PE, Alliet G, Simpelaere A, Desmet G. Lemierre’s syndrome: a case study with a short review of literature. Acta Clin Belgica Int J Clin Lab Med [Internet]. 2019;74(3):206–10. Available from: https://doi.org/10.1080/17843286.2018.1474614

  12. García-Salido A, Unzueta-Roch JL, García-Teresa MÁ, Sirvent-Cerdá S, Martínez De Azagra-Garde A, Casado-Flores J. Pediatric disseminated lemierre syndrome in 2 infants: Not too young for an ancient disease. Pediatr Emerg Care. 2017;33(7):490–3.

  13. Almohaya AM, Almutairy TS, Alqahtani A, Binkhamis K, Almajid FM. Fusobacterium bloodstream infections: A literature review and hospital-based case series. Anaerobe [Internet]. 2020;62:102165. Available from: https://doi.org/10.1016/j.anaerobe.2020.102165

  14. Huggan PJ, Murdoch DR. Fusobacterial infections: Clinical spectrum and incidence of invasive disease. J Infect [Internet]. 2008;57(4):283–9. Available from: http://dx.doi.org/10.1016/j.jinf.2008.07.016

  15. Riordan T. Human infection with Fusobacterium necrophorum (Necrobacillosis), with a focus on Lemierre’s syndrome. Clin Microbiol Rev. 2007;20(4):622–59.

  16. Mellor TE, Mitchell N, Logan J. Lemierre’s syndrome variant of the gut. BMJ Case Rep. 2017;2017:1–3.

  17. Van Hoecke F, Lamont B, Van Leemput A, Vervaeke S. A Lemierre-like syndrome caused by Staphylococcus aureus: an emerging disease. Infect Dis (Auckl) [Internet]. 2020;52(3):143–51. Available from: https://doi.org/10.1080/23744235.2019.1691255

  18. Valerio L, Zane F, Sacco C, Granziera S, Nicoletti T, Russo M, et al. Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: an analysis of 712 cases. J Intern Med. 2020;325–39.

  19. Patel PN, Levi JR, Cohen MB. Lemierre’s syndrome in the pediatric population: Trends in disease presentation and management in literature. Int J Pediatr Otorhinolaryngol [Internet]. 2020;136(April):110213. Available from: https://doi.org/10.1016/j.ijporl.2020.110213

  20. Oudsema R, Masseaux JA, Rosenberg HK. US of Pediatric Superficial Masses of the Head and Neck. 2018

  21. Paker M, Cohen JT, Moed N, Shleizerman L, Masalha M, Ashkenazi D, et al. Facial vein thrombophlebitis: A case report and literature review. Int J Pediatr Otorhinolaryngol [Internet]. 2018;113(August):298–301. Available from: https://doi.org/10.1016/j.ijporl.2018.08.015




2020     |     www.medigraphic.com