Corso-Restrepo DF, Solier Insuasty-Enríquez J, Oviedo-Pastrana DF, Anaya-Rodríguez AF

Idioma: Español
Referencias bibliográficas: 38
Paginas: 959-967
Archivo PDF: 212.40 Kb.

RESUMEN

Antecedentes: El cáncer de mama es la principal neoplasia en incidencia y mortalidad en mujeres. Los subtipos moleculares: luminal A, luminal B, HER2 y triple negativo tienen un pronóstico y tasas de supervivencia diferentes. En la bibliografía está demostrada la estrecha asociación entre los factores estímulo estrogénicos y el cáncer de mama en general, aunque las diferencias no son claras debido a los subtipos moleculares.
Objetivo: Revisar la bibliografía reciente y describir la relación entre los subtipos moleculares del cáncer de mama y los factores reproductivos.
Metodología: Búsqueda en las bases de datos PubMed y LILACS con los términos MeSH y DeCS: neoplasias de la mama, subtipos moleculares, factores de riesgo, factores reproductivos. Se buscó la asociación entre los antecedentes de paridad, edad al primer embarazo y el antecedente de lactancia materna con los subtipos moleculares de cáncer de mama: luminal A, luminal B y HER2.
Resultados: Se obtuvieron 366 artículos y se eliminaron 352 por: duplicidad en títulos y resúmenes, sin pertinencia para el tema, protocolos de investigación que no estudiaran la asociación entre factores estímulo estrogénicos con los subtipos moleculares de cáncer de mama. Al final, el análisis se hizo con 14 artículos.
Conclusiones: Los tumores con receptores hormonales positivos se asociaron con: edad mayor al primer embarazo, mayor tiempo entre la menarquia y el primer embarazo a término y edad avanzada en el último embarazo. Factores protectores para tumores luminales y HER2 puro: lactancia materna y multiparidad.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Kellerman RD, KUSM-W Medical Practice Association.Conn’s Current Therapy 2020, E-Book. Elsevier HealthSciences, 2019; 1472. https://play.google.com/store/books/details?id=cyDCDwAAQBAJ

2. Torre LA, Bray F, Siegel RL, Ferlay J, et al. Global cancerstatistics, 2012. Vol. 65, CA: A Cancer Journal for Clinicians2015; 87-108. http://dx.doi.org/10.3322

3. World Health Organization, International Agency forResearch on Cancer. The Global Cancer Observatory.2020 statistics. https://gco.iarc.fr/today/data/factsheets/populations/900-world-fact-sheets.pdf

4. Coates AS, Winer EP, Goldhirsch A, Gelber RD, et al.Tailoring therapies--improving the management of earlybreast cancer: St Gallen International Expert Consensuson the Primary Therapy of Early Breast Cancer 2015. AnnOncol 2015; 26 (8): 1533-46. http://dx.doi.org/10.1093/annonc/mdv221

5. Amadou A, Torres-Mejía G, Hainaut P, Romieu I. Breastcancer in Latin America: global burden, patterns, and riskfactors. Salud Publica Mex 2014; 56 (5): 547-54. http://dx.doi.org/10.21149/spm.v56i5.7379

6. Villarreal-Garza C, Aguila C, Magallanes-Hoyos MC, MoharA, et al. Breast cancer in young women in Latin America: anunmet, growing burden. Oncologist 2013; 18 (12): 1298-306. http://dx.doi.org/10.1634/theoncologist.2013-0321

7. Ramírez-Martínez CM, Clavijo-Rodríguez JM, Estrada-Restrepo J, Restrepo-Ramírez CA. Descripción clínica,anatomopatológica y de tratamiento de pacientes concáncer de mama en una unidad de mastología de la ciudadde Medellín, Colombia. 2006- 2013. CES MEDICINA.2015;29 (2): 181-90. http://dx.doi.org/10.4321/s0378-48352006000100003

8. Hedeen AN, White E. Breast cancer size and stage inHispanic American women, by birthplace: 1992-1995.Am J Public Health 2001; 91 (1): 122-5. http://dx.doi.org/10.2105/ajph.91.1.122

9. Rakha EA, El-Rehim DA, Paish C, Green AR, et al. Basalphenotype identifies a poor prognostic subgroup of breastcancer of clinical importance. Eur J Cancer 2006; 42 (18):3149-56. http://dx.doi.org/10.1016/j.ejca.2006.08.015

10. Rakha E, El-Rehim A, Putti T, Lee A, et al. Breast carcinomaswith basal phenotype: An appraisal of morphology andprognostic significance. European J Cancer Suppl 2006;4:113. http://dx.doi.org/10.1016/s1359-6349(06)80246-6

11. Sørlie T, Perou CM, Tibshirani R, Aas T, et al. Gene expressionpatterns of breast carcinomas distinguish tumorsubclasses with clinical implications. Proc Natl Acad Sci US A 2001; 98 (19): 10869-74. http://dx.doi.org/10.1073/pnas.191367098

12. Forouzanfar MH, Foreman KJ, Delossantos AM, LozanoR, et al. Breast and cervical cancer in 187 countries between1980 and 2010: a systematic analysis. Lancet 2011;378 (9801): 1461-84. http://dx.doi.org/10.1016/S0140-6736(11)61351-2

13. Ramírez K, Acevedo F, Herrera ME, Ibáñez C, et al. Actividadfísica y cáncer de mama: un tratamiento dirigido.Revista médica de Chile. 2017; 145: 75-84. http://dx.doi.org/10.4067/s0034-98872017000100011

14. Wolin KY, Schwartz AL, Matthews CE, Courneya KS, et al.Implementing the exercise guidelines for cancer survivors.J Support Oncol 2012; 10 (5): 171-7. http://dx.doi.org/10.1016/j.suponc.2012.02.001

15. Shantakumar S, Terry MB, Teitelbaum SL, Britton JA, et al.Reproductive factors and breast cancer risk among olderwomen. Breast Cancer Res Treat 2007; 102 (3): 365-74.http://dx.doi.org/10.1007/s10549-006-9343-4

16. Rosner B, Colditz GA, Willett WC. 94144079 Reproductiverisk factors in a prospective study of breast cancer: Thenurses’ health study. Maturitas 1994; 20: 224. http://dx.doi.org/10.1016/0378-5122(94)90030-2

17. Romero FMS, Santillán AL, Olvera HPC, Morales SMA, etal. Frecuencia de factores de riesgo de cáncer de mama.Ginecol Obstet Mex 2008; 76 (11): 667-72.

18. Ma H, Bernstein L, Pike MC, Ursin G. Reproductive factorsand breast cancer risk according to joint estrogen andprogesterone receptor status: a meta-analysis of epidemiologicalstudies. Breast Cancer Res 2006; 8 (4): R43. http://dx.doi.org/10.1186/bcr1525

19. Phipps AI, Malone KE, Porter PL, Daling JR, et al. Reproductiveand hormonal risk factors for postmenopausal luminal,HER-2-overexpressing, and triple-negative breast cancer.Cancer 2008; 113 (7): 1521-26. http://dx.doi.org/10.1002/cncr.23786

20. Ambrosone CB, Zirpoli G, Ruszczyk M, Shankar J, et al. Parityand breastfeeding among African-American women: differentialeffects on breast cancer risk by estrogen receptorstatus in the Women’s Circle of Health Study. Cancer CausesControl 2014; 25 (2): 259-65. http://dx.doi.org/10.1007/s10552-013-0323-9

21. Barnard ME, Boeke CE, Tamimi RM. Established breastcancer risk factors and risk of intrinsic tumor subtypes.Biochim Biophys Acta 2015; 1856 (1): 73-85. http://dx.doi.org/10.1016/j.bbcan.2015.06.002

22. Work ME, John EM, Andrulis IL, Knight JA, et al. Reproductiverisk factors and oestrogen/progesterone receptor-negative breast cancer in the Breast Cancer FamilyRegistry. Br J Cancer 2014; 110 (5): 1367-77. http://dx.doi.org/10.1038/bjc.2013.807

23. Islami F, Liu Y, Jemal A, Zhou J, et al. Breastfeeding andbreast cancer risk by receptor status -a systematic reviewand meta-analysis. Annals of Oncology 2015; 26: 2398-407.http://dx.doi.org/10.1093/annonc/mdv379

24. Romieu I, Biessy C, Carayol M, His M, et al. Reproductivefactors and molecular subtypes of breast cancer amongpremenopausal women in Latin America: the PRECAMAstudy. Sci Rep 2018; 8 (1): 13109. http://dx.doi.org/10.1038/s41598-018-31393-7

25. Ellingjord-Dale M, Vos L, Tretli S, Hofvind S, et al. Parity,hormones and breast cancer subtypes -Results from alarge nested case-control study in a national screeningprogram. Breast Cancer Research 2017;19. http://dx.doi.org/10.1186/s13058-016-0798-x

26. Lambertini M, Santoro L, Del Mastro L, Nguyen B, et al. Reproductivebehaviors and risk of developing breast canceraccording to tumor subtype: A systematic review and metaanalysisof epidemiological studies. Cancer Treat Rev 2016;49: 65-76. http://dx.doi.org/10.1016/j.ctrv.2016.07.006

27. Li C, Fan Z, Lin X, Cao M, et al. Parity and risk of developingbreast cancer according to tumor subtype: A systematicreview and meta-analysis. Cancer Epidemiol 2021; 75:102050. http://dx.doi.org/10.1016/j.canep.2021.102050

28. Wang JM, Wang J, Zhao HG, Liu TT, et al. ReproductiveRisk Factors Associated with Breast Cancer MolecularSubtypes among Young Women in Northern China.Biomed Res Int 2020; 2020: 5931529. http://dx.doi.org/10.1155/2020/5931529

29. Park S, Moon BI, Oh SJ, Lee H-B, et al. Clinical subtypes andprognosis in breast cancer according to parity: a nationwidestudy in Korean Breast Cancer Society. Breast Cancer ResTreat 2019; 173 (3): 679-91. http://dx.doi.org/10.1007/s10549-018-5032-3

30. Figueroa JD, Davis Lynn BC, Edusei L, Titiloye N, et al.Reproductive factors and risk of breast cancer by tumorsubtypes among Ghanaian women: A population-basedcase-control study. Int J Cancer 2020; 147 (6): 1535-47.http://dx.doi.org/10.1002/ijc.32929

31. Minami Y, Nishino Y, Kawai M, Tada H, et al. Reproductivehistory and breast cancer survival: a prospective patientcohort study in Japan. Breast Cancer 2019; 26 (6): 687-702.http://dx.doi.org/10.1007/s12282-019-00972-5

32. von Au A, Klotzbuecher M, Uhlmann L, Boudewijns M, et al.Impact of reproductive factors on breast cancer subtypesin postmenopausal women: a retrospective single-centerstudy. Arch Gynecol Obstet 2017; 295 (4): 971-8. http://dx.doi.org/10.1007/s00404-017-4298-8

33. Xing P, Li J, Jin F. A case-control study of reproductive factorsassociated with subtypes of breast cancer in NortheastChina. Med Oncol 2010; 27 (3): 926-31. http://dx.doi.org/10.1007/s12032-009-9308-7

34. Li H, Sun X, Miller E, Wang Q, et al. BMI, reproductive factors,and breast cancer molecular subtypes: A case-controlstudy and meta-analysis. J Epidemiol 2017; 27 (4): 143-51.http://dx.doi.org/10.1016/j.je.2016.05.002

35. Zhang L, Huang Y, Feng Z, Wang X, et al. Comparison ofbreast cancer risk factors among molecular subtypes: Acase-only study. Cancer Med 2019; 8 (4): 1882-92. http://dx.doi.org/10.1002/cam4.2012

36. Arteaga-Gómez AC, Zapata-Caballero CA, Arellano-EguiluzA, Santoyo-Rosas SE, et al. Terapia hormonal de reemplazoy riesgo de cáncer ginecológico en mujeres en el climaterio.Revisión narrativa. Ginecol Obstet Mex 2021; 89 (6): 464-71. https://doi.org/10.24245/gom. v89i6.5189

37. Alarcón Rojas CA, Alvarez-Bañuelos MT, Morales-Romero J,Suárez-Díaz H, et al. Breast Cancer: Metastasis, MolecularSubtypes, and Overweight and Obesity in Veracruz, Mexico.Clin Breast Cancer 2019; 19 (1): e166-71. http://dx.doi.org/10.1016/j.clbc.2018.08.003

38. Lope V, García-Esquinas E, Pérez-Gómez B, Altzibar JM, etal. Perinatal and childhood factors and risk of breast cancersubtypes in adulthood. Cancer Epidemiol 2016; 40: 22-30.http://dx.doi.org/10.1016/j.canep.2015.11.004.