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2022, Número 38

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INFODIR 2022; 18 (38)


Desarrollo, aplicaciones y desafíos de la nanomedicina

Jiménez HLG

Idioma: Español
Referencias bibliográficas: 52
Paginas: 1-24
Archivo PDF: 691.15 Kb.


RESUMEN

Introducción: La biotecnología facilita la construcción de herramientas que buscan mejorar las debilidades que presentan los medicamentos alopáticos.
Objetivo: Describir aspectos relacionados con la nanomedicina con mecanismos para la mejora en la atención y la calidad de vida de las personas.
Desarrollo: Se consideran aspectos conceptuales sobre nanotecnología, nanomedicina, nanoterapia, nanopartículas, nanomateriales, nanoportadores y la clasificación por áreas prácticas (diagnóstico, terapia, medicina regenerativa), dimensiones (cero, uni, bi, tri), mecanismos de acción (administración, estabilidad, liberación lenta y controlada, entre otras), nanosistemas, origen (natural, secundario o fabricado; metálicas/inorgánicas, no metálicas/orgánicas, organometálicas). Se enuncian retos a los que se enfrenta la nanomedicina y sus diversas ramas.
Conclusiones: En nanomedicina se diseñan, investigan e implementan diversas aplicaciones que buscan un mejor abordaje de situaciones que afectan la calidad de vida de las personas aun cuando persisten desafíos teórico-conceptuales, metodológicos (procedimientos estandarizados) y práctico-clínico (eficacia, seguridad, calidad, eficiencia) que deben ser superados.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Gómez M. Usos terapéuticos de nanomateriales y nanopartículas. Revista Repertorio de Medicina y Cirugía. 2019 [acceso 15/11/2021];28(1):5-11. Disponible en: https://revistas.fucsalud.edu.co/index.php/repertorio/article/view/871/900

  2. Dhiman N, Awasthi R, Sharmal B, Kharkwal H, Kulkarni G. Lipid nanoparticles as carriers for bioactive delivery. Frontiers in Chemistry. 2021 [acceso 12/11/2021];9:580118. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8107723/

  3. Fernández F, Diaz M, Delerue C, Grosso C. Critical Review of Lipid-Based Nanoparticles as Carriers of Neuroprotective Drugs and Extracts. Nanomaterials. 2021 [acceso 12/11/2021];11(563):1-43. Disponible en: https://www.mdpi.com/2079-4991/11/3/563

  4. Uskoković V. Health economics matters in the nanomaterial world: Cost-effectiveness of utilizing an inhalable antibacterial nanomaterial for the treatment of multidrug-resistant pneumonia. Technology in Society. 2021 [acceso 19/11/2021];66:101641. Disponible en: https://www.sciencedirect.com/science/article/pii/S0160791X21001160

  5. Delshadi R, Bahrami A, McClements D, Moore M, Williams L. Development of nanoparticle-delivery systems for antiviral agents: A review. Journal of Controlled Release. 2021 [acceso 12/11/2021];331:30-44. Disponible en: https://www.sciencedirect.com/science/article/pii/S0168365921000262

  6. Abbasi A, Haghjooy S, Asadnia M, Razmjou A. Recent advances in nanomaterials development for nanomedicine and cancer. ACS Applied Bio Materials. 2021 [acceso 12/11/2021];4(8):5908-25. Disponible en: https://pubs.acs.org/doi/abs/10.1021/acsabm.1c00591

  7. Afzal M, Alharbi K, Alruwaili N, Al-Abassi F, Al-Malki A, Kazmi I, et alt. Nanomedicine in treatment of breast cancer-A challenge to conventional therapy. In Seminars in cancer biology. Academic Press. 2021 [acceso 12/11/2021];69:279-92. Disponible en: https://www.sciencedirect.com/science/article/pii/S1044579X19304158

  8. Ertas Y, Dorcheh K, Akbari A, Jabbari E. Nanoparticles for Targeted Drug Delivery to Cancer Stem Cells: A Review of Recent Advances. Nanomaterials. 2021 [acceso 12/11/2021];11(1755):1-25. Disponible en: https://www.mdpi.com/2079-4991/11/7/1755

  9. Rama G, Dariya B, Kumar S, Chalikonda G, Kang S, Khan I, et al. Nanomaterials multifunctional behavior for enlightened cancer therapeutics. Seminars in cancer biology. 2021 [acceso 12/11/2021];69:168-89. Disponible en: https://www.sciencedirect.com/science/article/pii/S1044579X19301907

  10. Rahman M, Mohammad A. Cancer Nanotherapeutics: Targeted medicine, therapeutic vaccination and Challenges with cancer nanomedicines. Seminars in cancer biology. 2021 [acceso 12/11/2021];69:1-4. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33571666/

  11. Lim S, Cox A, Tung M, Chung E. Clinical progress of nanomedicine-based RNA therapies. Bioactive Materials. 2021 [acceso 14/11/2021]. Disponible en: https://www.sciencedirect.com/science/article/pii/S2452199X21004825

  12. Karaosmanoglu S, Zhou M, Shi B, Zhang X, Williams G, Chen X, et al. Carrier-free nanodrugs for safe and effective cancer treatment. Journal of Controlled Release. 2021 [acceso 14/11/2021];329:805-32. Disponible en: https://www.sciencedirect.com/science/article/pii/S016836592030585X

  13. Hu D, Zhang W, Tang J, Zhou Z, Liu X, Shen Y, et al. Improving safety of cancer immunotherapy via delivery technology. Biomaterials. 2021 [acceso 13/11/2021];265(120407):1-17. Disponible en: https://www.sciencedirect.com/science/article/pii/S0142961220306530

  14. Grewal I, Singh S, Arora S, Sharma N. Polymeric nanoparticles for breast cancer therapy: A comprehensive review. Biointerface Res. Appl. Chem. 2021 [acceso 18/11/2021];11:11151-71. Disponible en: https://biointerfaceresearch.com/wp-content/uploads/2020/12/20695837114.1115111171.pdf

  15. Khan H, Mirzaei H, Amiri A, Akkol E, Halimi S, Mirzaei H, et al. Glyco-nanoparticles: New drug delivery systems in cancer therapy. Seminars in cancer biology. 2021 [acceso 13/11/2021];69:24-42. Disponible en: https://www.sciencedirect.com/science/article/pii/S1044579X19304006

  16. Pawar K, Kachave R, Kanawade M, Zagre V. A Review on Nanoparticles Drug Delivery System. Journal of Drug Delivery and Therapeutics. 2021 [acceso 18/11/2021];11(4): 101-4. Disponible en: http://www.jddtonline.info/index.php/jddt/article/view/4865

  17. Wan Z, Sun R, Moharil P, Chen J, Liu Y, Song X, el at. Research advances in nanomedicine, immunotherapy, and combination therapy for leukemia. Journal of Leukocyte Biology. 2021 [acceso 19/11/2021];109(2):425-36. Disponible en: https://jlb.onlinelibrary.wiley.com/doi/abs/10.1002/JLB.5MR0620-063RR

  18. Martínez R, Becerra J, Marco M, Vicent M, Arenas J, Carracedo Á, et al. Informes anticipando nanomedicina. España: Fundación Instituto Roche, Observatorio de tendencias en la medicina del futuro. Ascendo Sanidad&Farma. 2021 [acceso 13/11/2021]. Disponible en: https://www.institutoroche.es

  19. Mitchell M, Billingsley M, Haley R, Wechsler M, Peppas N, Langer R, et al. Engineering precision nanoparticles for drug delivery. Nature Reviews Drug Discovery. 2021 [acceso 17/11/2021];20(2):101-24. Disponible en: https://www.nature.com/articles/s41573-020-0090-8

  20. Bulbake U, Doppalapudi S, Kommineni N, Khan W. Liposomal formulations in clinical use: an updated review. Pharmaceutics. 2017 [acceso 14/11/2021];9(2):12. Disponible en: https://www.mdpi.com/1999-4923/9/2/12

  21. Rojas Y, Aguado K, González I. La nanomedicina y los sistemas de liberación de fármacos: ¿la (r)evolución de la terapia contra el cáncer? Educación química. 2016;27(4):286-91. DOI: https://doi.org/10.106/j.eq.2016.07.02

  22. Rennick J, Johnston A, Parton R. Principles and methods for studying the endocytosis of biological and nanoparticle therapeutics. Nature Nanotechnology. 2021 [acceso 17/11/2021];16(3):266-76. Disponible en: https://www.nature.com/articles/s41565-021-00858-8

  23. Hoang T, Suys E, Lee J, Nguyen D, Park K, Truong N, et al. Lipid-Based Nanoparticles in the Clinic and Clinical Trials: From Cancer Nanomedicine to COVID-19 Vaccines. Vaccines. 2021 [acceso 15/11/2021];9(359):1-28. Disponible en: https://www.mdpi.com/2076-393X/9/4/359

  24. Suñé M, Limeres M, Moreno C, Hernández C, Suñé J, Cuestas M, et al. Innovative therapeutic and delivery approaches using nanotechnology to correct splicing defects underlying disease. Frontiers in Genetics. 2020 [acceso 13/11/2021];11(731):1-22. Disponible en: https://www.frontiersin.org/articles/10.3389/fgene.2020.00731/full

  25. Boix P, Soriano P, de Benito A, Orzáez M, Vicent M. The Past, Present, and Future of Breast Cancer Models for Nanomedicine Development. Advanced Drug Delivery Reviews. 2021 [acceso 18/11/2021];173: 306-30. Disponible en: https://www.sciencedirect.com/science/article/pii/S0169409X2100096X

  26. Anselmo A, Mitragotri S. Nanoparticles in the clinic: An update post COVID‐19 vaccines. Bioengineering & translational medicine. 2021 [acceso 17/11/2021];6(3):e10246. Disponible en: https://aiche.onlinelibrary.wiley.com/doi/full/10.1002/btm2.10246

  27. Márquez E, Hernández D, Míguez M, Soler F, Pérez M. Las nanopartículas y sus aplicaciones. España: Universidad de Extremadura. 2021 [acceso 18/11/2021]. Disponible en: https://dehesa.unex.es/handle/10662/11784

  28. Milewska S, Niemirowicz-Laskowska K, Siemiaszko G, Nowicki P, Wilczewska AZ, Car H, et al. Current Trends and Challenges in Pharmacoeconomic Aspects of Nanocarriers as Drug Delivery Systems for Cancer Treatment. International journal of nanomedicine. 2021 [acceso 17/11/2021];16:6593. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8487283/

  29. Yodsanit N, Wang B, Zhao Y, Guo L, Kent G, Gong S, et al. Recent progress on nanoparticles for targeted aneurysm treatment and imaging. Biomaterials. 2021 [acceso 14/11/2021];265(120406):1-15. Disponible en: https://www.sciencedirect.com/science/article/pii/S014296122030652946

  30. Massaro S, Lorenzoni G. Nanomedicine: a socio-technical system. Technological Forecasting and Social Change. 2021 [acceso 15/11/2021];173(121066):1-11. Disponible en: https://www.sciencedirect.com/science/article/pii/S0040162521004984

  31. Cote B, Rao D, Alani A. Nanomedicine for Drug Delivery throughout the Alimentary Canal. Molecular Pharmaceutics. 2021 [acceso 14/11/2021]. Disponible en: https://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.0c00694

  32. Hayat H, Nukala A, Nyamira A, Fan J, Wang P. A concise review: the synergy between artificial intelligence and biomedical nanomaterials that empowers nanomedicine. Biomedical Materials. 2021 [acceso 17/11/2021];16(052001):1-8. Disponible en: https://iopscience.iop.org/article/10.1088/1748-605X/ac15b2/meta

  33. Ren C, Wang Z, Zhang X, Gao J, Gao Y, Zhang Y, et al. Construction of all-in-one peptide nanomedicine with photoacoustic imaging guided mild hyperthermia for enhanced cancer chemotherapy. Chemical Engineering Journal. 2021 [acceso 19/11/2021];405(127008):1-10. Disponible en: https://www.sciencedirect.com/science/article/pii/S138589472033136333. Kim E, Lim E, Park G, Park C, Lim J, Lee H, et al. Advanced Nanomaterials for Preparedness Against (Re‐) Emerging Viral Diseases. Advanced Materials. 2021 [acceso 19/11/2021];2005927:1-32. Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1002/adma.202005927

  34. Maslanka S, Fleischmann D, Goepferich A. Biomedical nanoparticle design: What we can learn from viruses. Journal of Controlled Release. 2021 [acceso 19/11/2021];329:552-69. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33007365/

  35. Sargazi S, Mukhtar M, Radhar A, Barani M, Pandey S, Díez A, et al. Active Targeted Nanoparticles for Delivery of Poly (ADP-ribose) Polymerase (PARP) Inhibitors: A Preliminary Review. International Journal of Molecular Sciences. 2021 [acceso 11/11/2021];22(10319):1-19. Disponible en: https://www.mdpi.com/1422-0067/22/19/10319

  36. 36.Wu P, Zhang B, Wiredu D, Xu W, Qian H. Extracellular vesicles: A bright star of nanomedicine Extracellular vesicles: A bright star of nanomedicine. Biomaterials. 2021;269(120467):1-24. DOI: https://doi.org/10.1016/j.biomaterials.2020.120467

  37. 37.Chowdhury N, Deepika G, Chowdhury R, Sonawane G, Mavinamar S, Lyu X, Pandey R, et al. Nanoparticles as an Effective Drug Delivery System in COVID-19. Biomedicine & Pharmacotherapy. 2021 [acceso 19/11/2021];143:112162. Disponible en: https://www.sciencedirect.com/science/article/pii/S075333222100946X

  38. Basha S, Dhandayuthabani R, Syed M, Sugantha V. Solid lipid nanoparticles for oral drug delivery. Materials Today: Proceedings. 2021 [acceso 15/11/2021];(36):313-24. Disponible en: https://www.sciencedirect.com/science/article/pii/S2214785320327243

  39. 39.Sarraf M, Nasiri B, Yeong C, Hosseini H, Saber S, Basirun W, et al. Mixed oxide nanotubes in nanomedicine: A dead-end or a bridge to the future? Ceramics International. 2021 [acceso 16/11/2021];47(3):2917-48. Disponible en: https://www.sciencedirect.com/science/article/pii/S0272884220328820

  40. Yang Y, Santamaria P. Evolution of nanomedicines for the treatment of autoimmune disease: from vehicles for drug delivery to inducers of bystander immunoregulation. Advanced Drug Delivery Reviews. 2021 [acceso 15/11/2021];176(113898):1-12. Disponible en: https://www.sciencedirect.com/science/article/pii/S0169409X2100291X

  41. Sofias A, Combes F, Koschmieder S, Storm G, Lammers T. A paradigm shift in cancer nanomedicine: From traditional tumor targeting to leveraging the immune system. Drug discovery today. 2021 [acceso 17/11/2021];26(6):1482-9. Disponible en: https://www.sciencedirect.com/science/article/pii/S1359644621001008

  42. Caldonazo A, Almeida S, Bonetti A, Lazo R, Mengarda M, Murakami F, et al. Pharmaceutical applications of starch nanoparticles: A scoping review. International Journal of Biological Macromolecules. 2021 [acceso 15/11/2021];181:697-704. Disponible en: https://www.sciencedirect.com/science/article/pii/S014181302100578X

  43. Amiri M, Mohammadzadeh V, Yazdi M, Barani M, Rahdar A, Kyzas G, et al. Plant-Based Gums and Mucilages Applications in Pharmacology and Nanomedicine: A Review. Molecules. 2021 [acceso 14/11/2021];26(1770):1-23. Disponible en: https://www.mdpi.com/1420-3049/26/6/1770

  44. Qambrani A, Rehman F, Tanziela T, Shaikh S, Semcheddine F, Du T, et al Biocompatible exosomes nanodrug cargo for cancer cell bioimaging and drug delivery. Biomedical Materials. 2021 [acceso 13/11/2021];16(025026):1-14. Disponible en:https://iopscience.iop.org/article/10.1088/1748-605X/abaaa2/meta

  45. Gao X, Li L, Cai X, Huan Q, Xiao T, Cheng Y, et al. Targeting nanoparticles for diagnosis and therapy of bone tumors: Opportunities and challenges. Biomaterials. 2021 [acceso 15/11/2021];265(120404):1-21. Disponible en: https://www.sciencedirect.com/science/article/pii/S0142961220306505

  46. Sanitá G, Carrese B, Lamberti A. Nanoparticle surface functionalization: how to improve biocompatibility and cellular internalization. Frontiers in molecular biosciences. 2020 [acceso 17/11/2021];7(587012):1-20. Disponible en: https://www.frontiersin.org/articles/10.3389/fmolb.2020.587012/full

  47. Varahachalam S, Lahooti B, Chamaneh M, Bagchi S, Chhibber T, Morris K, et al. Nanomedicine for the SARS-CoV-2: state-of-the-art and future prospects. International journal of nanomedicine. 2021 [acceso 11/11/2021];16:539. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837559/

  48. Gul AR, Shaheen F, Rafique R, Bal J, Waseem S, Park TJ, et al. Grass-mediated biogenic synthesis of silver nanoparticles and their drug delivery evaluation: A biocompatible anti-cancer therapy. Chemical Engineering Journal. 2021 [acceso 18/11/2021];407:127202. Disponible en: https://www.sciencedirect.com/science/article/pii/S1385894720333295

  49. Zhang X, Duan X, Hu Y, Tang Z, Miao C, Tao W, et al. One-step and facile synthesis of peptide-like poly (melphalan) nanodrug for cancer therapy. Nano Today. 2021 [acceso 17/11/2021];37(101098):1-12. Disponible en: https://www.sciencedirect.com/science/article/pii/S1748013221000232?via%3Dihub

  50. Mahajan R. Onasemnogene abeparvovec for spinal muscular atrophy: The costlier drug ever. Int J App Basic Med Res. 2019;9:127-8. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652281/pdf/IJABMR-9-127.pdf

  51. Lu L, Sun Y, Wan C, Hu Y, Lo P, Lovell J, et al. Role of intravital imaging in nanomedicine-assisted anti-cancer therapy. Current Opinion in Biotechnology. 2021 [acceso 19/11/2021];69:153-61. Disponible en: https://pubmed.ncbi.nlm.nih.gov/33476937/

  52. Gupta N, Bahl S, Bagha A, Vaid S, Javaid M, Haleem A, et al. Nanomedicine technology and COVID-19 outbreak: Applications and challenges. Journal of Industrial Integration and Management. 2021 [acceso 11/11/2021]. Disponible en: https://www.worldscientific.com/doi/abs/10.1142/S2424862221500123




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