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Asociación Mexicana de Gastroenterología

2007, Número 1

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Rev Gastroenterol Mex 2007; 72 (1)


Daño intestinal por antiinflamatorios no esteroideos

Rocha RJL, Parrado MJW, Rojas IM, Sierra ME, Soto QR, Fernández RJM

Idioma: Español
Referencias bibliográficas: 21
Paginas: 43-46
Archivo PDF: 97.02 Kb.


RESUMEN

Antecedentes: las drogas antiinflamatorias no esteroideas (AINEs), son los medicamentos más ampliamente prescritos en el mundo, con alto índice de complicaciones por daño gastrointestinal. Objetivo: presentar dos casos clínicos de daño intestinal asociado a la ingesta crónica de AINEs. Método: se presenta un caso clínico con enfermedad inflamatoria intestinal con enteropatía del yeyuno y otro caso asociado a hemorragia digestiva baja con demostración endoscópica de úlceras en colon derecho. Conclusión: los pacientes con ingesta de AINEs que cursan con diarrea, hemorragia, desnutrición o anemia hay que descartar daño intestinal.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Sun DC, Roth SH, Mitchell CS, Englund DW. Upper gastrointestinal diseases in rheumatoid arthritis. Am J Dig Dis 1974; 19: 405-10.

  2. Levy M. Aspirin use in patients with major upper gastrointestinal bleeding and peptic ulcer disease: a report from the Boston Collaborative Drug Surveillance Program. N Engl J Med 1974; 290: 1159-62.

  3. Etienney I, Beaugerie L, Viboud C, Flahault A. Non-steroidal anti-inflammatory drugs as a risk factor for acute diarrhoea: a case crossover study. Gut 2003; 52: 260-3.

  4. Khan AZ, George K, Defriend J. Nonsteroidal anti-inflammatory drug-induced colonic stenosis: an unusual cause of a right-sided colonic mass. Dis Colon Rectum 2003; 46: 403-5.

  5. Püspök A, Kiener HP, Oberhuber G. Clinical, endoscopic, and histologic spectrum of nonsteroidal anti-inflammatory drug-induced lesions in the colon. Dis Colon Rectum 2000; 43: 685-91.

  6. Berg D, Zhang J, Weinstock J, et al. Rapid development of colitis in NSAID-Treated IL-10-deficient mice. Gastroenterology 2002; 123: 1527-42.

  7. Bjarnason I, Hayllar J, Smethurst, et al. Metronidazole reduces intestinal inflammation and blood loss in non-steroidal anti-inflammatory drug induce enteropathy. Gut 1992; 33: 1204-8.

  8. Bjarnason I, Hayllar J, Macpherson A, Russell A. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology 1993; 104: 1832-47.

  9. Milles A, Howatson A, Torrance C, et al. Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs. New Engl J Med 1992, 327: 749-54.

  10. Davies N. Toxicity of nonsteroidal anti-inflammatory drugs in the large intestine. Dis Colon Rectum 1995; 38: 1311-21.

  11. Bridges A, Marshall J, Diaz-Arias A. Acute eosinophilic colitis and hypersensitivity reaction associated with naproxen therapy. Am J Med 1990; 89: 526-7.

  12. Gizzi G, Villani V, Brandi G, et al. Ano-rectal lesions in patients taking suppositories containing non-steroidal anti-inflammatory drugs. Endoscopy 1990; 22; 146-8.

  13. Kurahara K, Matsumoto T, Iida M, et al. Clinical and endoscopic features of nonsteroidal anti-inflammatory drug-induced colonic ulcerations. Am J Gastroenterology 2001; 96: 473-80.

  14. Felder J, Korelitz B, Rajapakse R, et al. Effects of nonsteroidal antiinflammatory drugs on inflammatory bowel disease: a case-control study. Am J Gastroenterology 2000; 95: 1949-54.

  15. Corder A. Steroids non-steroidal anti-inflammatory drugs, and serious septic complications of diverticular disease. BMJ 1987; 295: 1238.

  16. Bjarnason I, Fehilly B, Smethurst IS, et al. Importance of local versus systemic effects of non-steroidal anti-inflammatory drugs in increasing small intestinal permeability in man. Gut 1991; 32: 275-7.

  17. Bjarnason I, Zanelli G, Smith T, et al. Nonsteroidal anti-inflammatory drug-induced intestinal inflammation in humans. Gastroenterology 1987; 93: 480-9.

  18. Bjarnason I, Williams P, Smethurst P, et al. The effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine. Gut 1986; 27: 1292-7.

  19. Robert A. Cytoproduction by prostaglandins. Gastroenterology 1979; 77: 761-7.

  20. Israel L, Koea J, Stewart I, et al. Nonsteroidal anti-inflammatory drug-induced strictures of the colon. Dis Colon Rectum 2001; 44: 1362-4.

  21. Yamagiwa S, Yoshida Y, Halder RC, et al. Mechanisms involved in enteropathy induced by administration of nonsteroidal antiinflammatory drugs (NSAIDS). Dig Dis Sci 2001; 46: 192-9.




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