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2009, Número 2

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Ann Hepatol 2009; 8 (2)


Pharmacokinetics of acemetacin and its active metabolite indomethacin in rats during acute hepatic damage and liver regeneration

Chávez-Piña AE, Favari L, Castañeda-Hernández G
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Idioma: Ingles.
Referencias bibliográficas: 25
Paginas: 141-147
Archivo PDF: 132.25 Kb.


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REFERENCIAS (EN ESTE ARTÍCULO)

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  2. Jacobi H, Dell HD. On the pharmacodynamics of acemetacin. Arzneimittelforschung 1980; 30: 1348–62.

  3. Bori-Segura G, Torres A, Herrera LE, Olguín J. Efficacy and tolerability of acemetacin, a non-steroidal anti-inflammatory drug, in Mexican patients: result of the ETAPAM study. Proc West Pharmacol Soc 2002; 45: 104–7.

  4. Chou CT, Tsai YY. A double-blind, randomized, controlled parallel group study evaluating the efficacy and safety of acemetacin for the management of osteoarthritis. Int J Clin Pharmacol Res 2002; 22: 1–6.

  5. Jones RW, Collins AJ, Notarianni LJ, Sedman E. The comparative pharmacokinetic of acemetacin in young subjects and elderly patients. Br J Clin Pharmacol 1991; 31: 543–45.

  6. Dell HD, Doersing M, Jacobi H, Kamp R. Biochemical studies on Acemetacin experimental test in animals. Arzneimittelforschung 1980; 30(II): 1371-83.

  7. Surborg H. Comparative metabolic studies on 14C-labelled acemetacin and indomethacin in rats. Arzneimittelforschung 1980; 30(II): 1384-91.

  8. Dell HD, Doersing M, Fischer W, Jacobi H, Kamp R, Köhler G, Schöllnhammer G. Metabolism and pharmacokinetics of acemetacin in man. Arzneimittelforschung 1980; 30(II): 1391-98.

  9. Li DM, Lu WL, Wang XQ, Wang JC, Zhang H, Zhan RJ, Wang GL, et al. Pharmacokinetics of indomethacin, a metabolite of acemetacin, following a single dose and multiple doses administered as acemetacin sustained-release tablets in healthy male volunteers. Journal of Health Science 2005; 51(3): 308-16.

  10. Chávez-Piña AE, McKnight W, Dicay M, Castañeda-Hernández G, Wallace JL. Mechanism underlying the anti-inflammatory activity and gastric safety of acemetacin. Br J Pharmacol 2007; 152(6): 930-38.

  11. Chávez-Piña AE, Vong L, McKnight W, Dicay M, Zanardo RC, Ortiz MI, Castañeda-Hernández G, Wallace JL. Lack of effects of acemetacin on signalling pathways for leukocyte adherence may explain its gastrointestinal safety. Br J Pharmacol 2008; 155(6):857-64.

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  15. Reyes-Gordillo K, Muriel P, Castañeda-Hernández G, Favari L. Pharmacokinetic of diclofenac in rats intoxicated with CCl4 and in the regenerating liver. Biopharm Drug Dispos 2007; 28:415-22.

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Ann Hepatol. 2009;8

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