Entrar/Registro  
INICIO ENGLISH
 
Revista Biomédica
   
MENÚ

Contenido por año, Vol. y Num.

Índice de este artículo

Información General

Instrucciones para Autores

Mensajes al Editor

Directorio






>Revistas >Revista Biomédica >Año 2008, No. 3


Martínez-Rodríguez PA, Kourí-Cardellá V
Mecanismos de transmisión del Herpesvirus humano 8: un reto actual
Rev Biomed 2008; 19 (3)

Idioma: Español
Referencias bibliográficas: 53
Paginas: 170-178
Archivo PDF: 0. Kb.


Texto completo




RESUMEN

Actualmente se reconoce la participación del Herpesvirus Humano 8 (Hvh-8) o Herpesvirus Asociado al Sarcoma de Kaposi (HASK) en las cuatro variantes clínicas del Sarcoma de Kaposi (SK) (clásico, endémico, iatrogénico y epidémico), en el Linfoma de Efusión Primaria (LEP) y en la Enfermedad Multicéntrica de Castleman (EMC).
En la presente revisión se presentan y discuten las principales hipótesis sobre la transmisión de este virus oncogénico, ya que actualmente no se han podido esclarecer categóricamente los mecanismos de la patogenia de su infección ni las vías de transmisión humano-humano. Aunque el SK no es una enfermedad frecuente en Cuba, los resultados de estudios realizados por autores cubanos han demostrado la presencia de este agente en nuestro país y su asociación con las variantes del SK epidémico y clásico en individuos cubanos.
El conocimiento de los posibles mecanismos involucrados en el paso de un individuo a otro definirá las posibles acciones para la reducción de la infección por el HASK, especialmente en grupos de mayor riesgo.


Palabras clave: transmisión, Sarcoma de Kaposi, Herpesvirus humano 8, SIDA, VIH, transfusiones, transplante.


REFERENCIAS

  1. Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi’s sarcoma. Science 1994; 266:1865-9.

  2. Hengge UR, Ruzicka T, Tyring SK, Stuschke M, Roggendorf M, Schwartz RA, et al. Update on Kaposi’s sarcoma and other HHV8 associated diseases. Part 1: epidemiology, environmental predispositions, clinical manifestations, and therapy. Lancet Infect Dis 2002; 2:281-92.

  3. Sarek G, Ojala PM. p53 reactivation kills KSHV lymphomas efficiently in vitro and in vivo: new hope for treating aggressive viral lymphomas. Cell Cycle 2007; 6:2205-9.

  4. Du MQ, Bacon CM, Isaacson PG. Kaposi sarcomaassociated herpesvirus/human herpesvirus 8 and lymphoproliferative disorders. J Clin Pathol 2007; 60:1350-7.

  5. Pyakurel P, Pak F, Mwakigonja AR, Kaaya E, Biberfeld P. KSHV/HHV-8 and HIV infection in Kaposi’s sarcoma development. Infect Agent Cancer 2007; 2:4.

  6. Guttman-Yassky E, Dubnov J, Kra-Oz Z, Friedman-Birnbaum R, Silbermann M, Barchana M, et al. Classic Kaposi sarcoma. Which KSHV-seropositive individuals are at risk? Cancer 2006; 106:413-9.

  7. Yee S, Varona J, Díaz C. Variantes clínicas del Sarcoma hemorrágico de Kaposi. Rev Cub Med 1981; 20:360-365.

  8. Fernandez L, Serraino D, Rezza G, Lence J, Ortiz RM, Cruz T, et al. Infection with human herpesvirus type 8 and human T-cell leukaemia virus type 1 among individuals participating in a case-control study in Havana City, Cuba. Br J Cancer 2002; 87:1253-6.

  9. Kouri V, Eng SM, Rodriguez ME, Resik S, Orraca O, Moore PS, et al. Seroprevalence of Kaposi’s sarcomaassociated herpesvirus in various populations in Cuba. Rev Panam Salud Pública 2004; 15:320-5.

  10. Kouri V, Martínez PA, Acosta B, Rodriguez ME, Blanco O, Capo V, et al. First report of Kaposi’s sarcoma-associated herpesvirus DNA sequences from Cuban Kaposi’s sarcoma patients without HIV infection. Aids 2007; 21:2113-5.

  11. Pérez A, Molina S, Mármol A, Pérez JC, Herrera M, Parodis Y. Sarcoma de Kaposi en el paciente receptor de un trasplante renal. Presentación de 1 caso. Rev Cub Med 2004; 43:1-5.

  12. Lebbe C. Humanes herpesvirus 8 (HHV-8) and Kaposi sarcoma. Hautarzt 2008; 59:18-25.

  13. Rimar D, Rimar Y, Keynan Y. Human herpesvirus-8: beyond Kaposi’s. Isr Med Assoc J 2006; 8:489-93.

  14. Zavitsanou A, Sypsa V, Petrodaskalaki M, Kalapothaki V, Whitby D, Hatzakis A. Human herpesvirus 8 (HHV-8) infection in healthy urban employees from Greece: seroprevalence and associated factors. J Med Virol 2007; 79:591-6.

  15. Machado DM, Sumita LM, Pannuti CS, Succi RC, Moraes-Pinto MI, Souza VA. Seroprevalence of human herpesvirus 8 infection in children born to HIV-1-infected women in Sao Paulo, Brazil. Braz J Med Biol Res 2005; 38:237-40.

  16. Sarmati L. HHV-8 infection in African children. Herpes 2004; 11:50-3.

  17. Cook RD, Hodgson TA, Molyneux EM, Borgstein E, Porter SR, Teo CG. Tracking familial transmission of Kaposi’s sarcoma-associated herpesvirus using restriction fragment length polymorphism analysis of latent nuclear antigen. J Virol Methods 2002; 105:297-303.

  18. Alkharsah KR, Dedicoat M, Blasczyk R, Newton R, Schulz TF. Influence of HLA Alleles on Shedding of Kaposi Sarcoma-Associated Herpesvirus in Saliva in an African Population. J Infect Dis 2007; 195:809-16.

  19. Wojcicki JM. Traditional behavioural practices, the exchange of saliva and HHV-8 transmission in sub-Saharan African populations. Br J Cancer 2003; 89:2016-7.

  20. Dedicoat M, Newton R, Alkharsah KR, Sheldon J, Szabados I, Ndlovu B, et al. Mother-to-child transmission of human herpesvirus-8 in South Africa. J Infect Dis 2004; 190:1068-75.

  21. Brayfield BP, Kankasa C, West JT, Muyanga J, Bhat G, Klaskala W, et al. Distribution of Kaposi sarcoma-associated herpesvirus/human herpesvirus 8 in maternal saliva and breast milk in Zambia: implications for transmission. J Infect Dis 2004; 189:2260-70.

  22. Calabro ML, Gasperini P, Barbierato M, Ometto L, Zanchetta M, De Rossi A, et al. A search for human herpesvirus 8 (HHV-8) in HIV-1 infected mothers and their infants does not suggest vertical transmission of HHV-8. Int J Cancer 2000; 85:296-7.

  23. Sarmati L, Carlo T, Rossella S, Montano M, Adalgisa P, Rezza G, et al. Human herpesvirus-8 infection in pregnancy and labor: lack of evidence of vertical transmission. J Med Virol 2004; 72:462-6.

  24. Mbulaiteye S, Marshall V, Bagni RK, Wang CD, Mbisa G, Bakaki PM, et al. Molecular evidence for mother-to-child transmission of Kaposi sarcoma-associated herpesvirus in Uganda and K1 gene evolution within the host. J Infect Dis 2006; 193:1250-7.

  25. Lisco A, Barbierato M, Fiore JR, Gasperini P, Favia A, Volpe A, et al. Pregnancy and human herpesvirus 8 reactivation in human immunodeficiency virus type 1-infected women. J Clin Microbiol 2006; 44:3863-71.

  26. Henke-Gendo C, Schulz TF. Transmission and disease association of Kaposi’s sarcoma-associated herpesvirus: recent developments. Curr Opin Infect Dis 2004; 17:53-7.

  27. Lavreys L, Chohan B, Ashley R, Richardson BA, Corey L, Mandaliya K, et al. Human herpesvirus 8: seroprevalence and correlates in prostitutes in Mombasa, Kenya. J Infect Dis 2003; 187:359-63.

  28. Eltom MA, Mbulaiteye SM, Dada AJ, Whitby D, Biggar RJ. Transmission of human herpesvirus 8 by sexual activity among adults in Lagos, Nigeria. Aids 2002; 16:2473-8.

  29. Mbulaiteye SM, Pfeiffer RM, Whitby D, Brubaker GR, Shao J, Biggar RJ. Human herpesvirus 8 infection within families in rural Tanzania. J Infect Dis 2003; 187:1780-5.

  30. Baeten JM, Chohan BH, Lavreys L, Rakwar JP, Ashley R, Richardson BA, et al. Correlates of human herpesvirus 8 seropositivity among heterosexual men in Kenya. Aids 2002; 16:2073-8.

  31. Plancoulaine S, Gessain A, van Beveren M, Tortevoye P, Abel L. Evidence for a recessive major gene predisposing to human herpesvirus 8 (HHV-8) infection in a population in which HHV-8 is endemic. J Infect Dis 2003; 187:1944-50.

  32. Marcelin AG, Grandadam M, Flandre P, Nicand E, Milliancourt C, Koeck JL, et al. Kaposi’s sarcoma herpesvirus and HIV-1 seroprevalences in prostitutes in Djibouti. J Med Virol 2002; 68:164-7.

  33. Crum NF, Wallace MR, Stephan K, Blazes DL, Aronson N, Tasker SA, et al. Correlates of human herpesvirus-8 seropositivity among U.S. military members recently infected with human immunodeficiency virus. Sex Transm Dis 2003; 30:713-8.

  34. Martro E, Esteve A, Schulz TF, Sheldon J, Gambus G, Munoz R, et al. Risk factors for human Herpesvirus 8 infection and AIDS-associated Kaposi’s sarcoma among men who have sex with men in a European multicentre study. Int J Cancer 2007; 120:1129-35.

  35. Dukers NH, Rezza G. Human herpesvirus 8 epidemiology: what we do and do not know. Aids 2003; 17:1717-30.

  36. Pica F, Volpi A. Transmission of human herpesvirus 8: an update. Curr Opin Infect Dis 2007; 20:152-6.

  37. Szajerka T, Jablecki J. Kaposi’s sarcoma revisited. AIDS Rev 2007; 9:230-6.

  38. Monini P, Howard MR, Rimessi P, de Lellis L, Schulz TF, Cassai E. Human herpesvirus DNA in prostate and semen from HIV-negative individuals in Italy. Aids 1997; 11:1530-2.

  39. Pauk J, Huang ML, Brodie SJ, Wald A, Koelle DM, Schacker T, et al. Mucosal shedding of human herpesvirus 8 in men. N Engl J Med 2000; 343:1369-77.

  40. Engels EA, Atkinson JO, Graubard BI, McQuillan GM, Gamache C, Mbisa G, et al. Risk Factors for Human Herpesvirus 8 Infection among Adults in the United States and Evidence for Sexual Transmission. J Infect Dis 2007; 196:199-207.

  41. Hladik W, Dollard SC, Mermin J, Fowlkes AL, Downing R, Amin MM, et al. Transmission of human herpesvirus 8 by blood transfusion. N Engl J Med 2006; 355:1331-8.

  42. Bendsoe N, Dictor M, Blomberg J, Agren S, Merk K. Increased incidence of Kaposi sarcoma in Sweden before the AIDS epidemic. Eur J Cancer 1990; 26:699-702.

  43. Velez-Garcia E, Robles-Cardona N, Fradera J. Kaposi’s sarcoma in transfusion-associated AIDS. N Engl J Med 1985; 312:648.

  44. Moore PS, Chang Y, Jaffe HW. Transmission of human herpesvirus 8 by blood transfusion. N Engl J Med 2007; 356:88; author reply 89.

  45. Pellett PE, Wright DJ, Engels EA, Ablashi DV, Dollard SC, Forghani B, et al. Multicenter comparison of serologic assays and estimation of human herpesvirus 8 seroprevalence among US blood donors. Transfusion 2003; 43:1260-8.

  46. Dollard SC, Nelson KE, Ness PM, Stambolis V, Kuehnert MJ, Pellett PE, et al. Possible transmission of human herpesvirus-8 by blood transfusion in a historical United States cohort. Transfusion 2005; 45:500-3.

  47. Atkinson J, Edlin BR, Engels EA, Kral AH, Seal K, Gamache CJ, et al. Seroprevalence of human herpesvirus 8 among injection drug users in San Francisco. J Infect Dis 2003; 187:974-81.

  48. Cannon MJ, Dollard SC, Smith DK, Klein RS, Schuman P, Rich JD, et al. Blood-borne and sexual transmission of human herpesvirus 8 in women with or at risk for human immunodeficiency virus infection. N Engl J Med 2001; 344:637-43.

  49. Renwick N, Dukers NH, Weverling GJ, Sheldon JA, Schulz TF, Prins M, et al. Risk factors for human herpesvirus 8 infection in a cohort of drug users in the Netherlands, 1985-1996. J Infect Dis 2002; 185:1808-12.

  50. Harwood AR, Osoba D, Hofstader SL, Goldstein MB, Cardella CJ, Holecek MJ, et al. Kaposi’s sarcoma in recipients of renal transplants. Am J Med 1979; 67:759-65.

  51. Marcelin AG, Calvez V, Dussaix E. KSHV after an organ transplant: should we screen? Curr Top Microbiol Immunol 2007; 312:245-62.

  52. Farge D, Lebbe C, Marjanovic Z, Tuppin P, Mouquet C, Peraldi MN, et al. Human herpes virus-8 and other risk factors for Kaposi’s sarcoma in kidney transplant recipients. Groupe Cooperatif de Transplantation d’ Ile de France (GCIF). Transplantation 1999; 67:1236-42.

  53. Barozzi P, Bosco R, Vallerini D, Potenza L, Torelli G, Luppi M, et al. KSHV/HHV-8 infection of tubular epithelial cells in transplantation kidney. Transplantation 2006; 82:851-2.



>Revistas >Revista Biomédica >Año2008, No. 3
 

· Indice de Publicaciones 
· ligas de Interes 






       
Derechos Resevados 2019