Peña OJ, Chávez BJMI

Idioma: Español
Referencias bibliográficas: 22
Paginas: 40-45
Archivo PDF: 392.04 Kb.

RESUMEN

Las enfermedades ampollosas como el pénfigo vulgar, el penfigoide, la epidermolisis bulosa adquirida (EBA), y la enfermedad IgA lineal son el resultado de una respuesta inmune anormal contra las proteínas de los desmosomas o de la membrana basal. La epidermolisis bulosa adquirida es una patología poco frecuente, con una prevalencia de 0.2 por millón de habitantes. No existe predilección de raza o sexo. Para realizar un diagnóstico certero se requiere el empleo de técnicas de biología molecular e inmunohistoquímica. En el presente artículo hacemos una revisión de los aspectos moleculares actuales en la patogenia de esta enfermedad.

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