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2009, Número 588

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Rev Med Cos Cen 2009; 66 (588)


Trombocitopenia inducida por heparina

Leiva HJ
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Idioma: Español
Referencias bibliográficas: 23
Paginas: 147-149
Archivo PDF: 219.39 Kb.


PALABRAS CLAVE

heparina no fraccionada, heparina de bajo peso molecular, factor plaquetario 4, trombocitopenia, fenómenos tromboticos.

RESUMEN

La trombocitopenia inducida por heparina (TIH) es de origen inmunológico y se produce mas frecuentemente tras la exposición a heparina no fraccionada (HNF), aunque se puede dar con el uso de heparina de bajo peso molecular (HBPM). Un porcentaje importante se acompaña de fenómenos tromboticos que pueden llegar a ser mortales si no se tratan adecuadamente. Es mas frecuente en pacientes quirúrgicos que médicos y se produce por anticuerpos de tipo IgG contra complejos de factor 4 plaquetario (PF4) y heparina.


REFERENCIAS (EN ESTE ARTÍCULO)

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