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>Revistas >Revista Mexicana de Anestesiología >Año 2012, No. 4


Molina-Méndez FJ
Entendiendo el pasado
Rev Mex Anest 2012; 35 (4)

Idioma: Español
Referencias bibliográficas: 18
Paginas: 233-237
Archivo PDF: 68.93 Kb.


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FRAGMENTO

Farmacogenética, farmacogenómica y el anestesiólogo

La práctica de la anestesia ha sido considerada por muchos años un arte y una ciencia, con una variabilidad interpaciente de respuesta a las drogas como la regla más que la excepción.
La farmacogenética es definida como: el estudio de los mecanismos bioquímicos que fundamentan las diferencias individuales en el metabolismo de las drogas, eficacia y efectos colaterales.


Palabras clave: Sin palabras Clave


REFERENCIAS

  1. Lostch J, Skarke C, Jurgen L, Geisslinger G. Nenetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives. Clinical Pharmacokinetics 2004;43:983-1013.

  2. Fishbain DA, Fishbain D, Lewis J, et al. Genetic testing for enzymes of drug metabolism: does it have clinical utility for pain medicine at the present time? A structured review. Pain Med 2004;5:81-93.

  3. Iohom G, Fitzgerald D, Cunningham AJ. Principles of pharmacogenetics: implications for the anaesthetics. Br J Anaesth 2004;93:440-450.

  4. Palmer SN, Gieseke NM, Body SC, et al. Pharmacogenetics of anesthesia and analgesic agents. Anesthesiology 2005;102:663-671.

  5. Lehmann H, Ryan E. The familial incidence of low pseudocholinesterse level. Lancet 1956;271:124.

  6. Kalow W, Gun DR. The relation between dose of succinylcoline and duration of apnea in man. The journal of pharmacology and experimental therapeutics 1957;120:203-214.

  7. Weinshilboum R. Inheritance and drug response. N Engl J Med 2003;348:529-537.

  8. Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies JAMA 1998;279:1200-1215.

  9. Landau R, Bollag LA, Kraft JC. Pharmacogenetics and anesthesia: the value of genetic profiling. Anaesthesia 2012;67:165-179.

  10. Wilkinson GR. Drug metabolism and variability among patients in drug response. N Eng J Med 2005;352:2211-2221.

  11. Amma T, Bounmythavong S, Blaze J, et al. Implications of pharmacogenomics for anesthesia providers. ANNA Journal 2010;78:393-399.

  12. Schuldiner AR, O´Connell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. Journal of the American Medical Association 2009;302:849-857.

  13. Sofi S, Giusti B, Marcucci R, et al. Cytochrome P4502C19(*)2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: a meta-analysis. Pharmacogenomics Journal 2011;11:199-206.

  14. Mega JL, Simon T, Cllet JP, et al. Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. Journal of the American Medical Association 2010;304:1821-1830.

  15. Gilard M, Arnaud B, Cornily JC, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole Clopidogrel Aspirin) study. Journal of the American College of Cardiology 208;51:256-260.

  16. Gilar M, Arnaud B, Le Gal G, et al. Influence of omeprazole on the antiplatelet action of clopidogrel associated to aspirin. Journal of Thrombosis and Haemostasis 2006;4:2508-2509.

  17. Dutchen S. The many mysteries of anesthesia. Live Science 2011.http://livescience.com/health/anesthesia-mysteries-nih-110126.html/National Institutes of health

  18. Searle R, Hopkins PM. Pharmacogenomic variability and anesthesia. Br J Anesth 2009;103:14-25.



>Revistas >Revista Mexicana de Anestesiología >Año2012, No. 4
 

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