García AH, MorenoD, Garmendia JV, De Sanctis JB

Idioma: Español
Referencias bibliográficas: 63
Paginas: 299-305
Archivo PDF: 270.84 Kb.

RESUMEN

En los últimos años se han estudiado un gran número de biomarcadores en asma y enfermedad pulmonar obstructiva crónica (EPOC). Un biomarcador debe tener las siguientes características: a) relevancia clínica, b) sensibilidad y especificidad, c) confiabilidad y reproducibilidad, d) facilidad en su medición y obtención. Las muestras en las que se pueden determinar los biomarcadores pueden provenir de diferentes fuentes (lavado bronquioalveolar, esputo, aire exhalado y sangre) y ofrecen información complementaria para establecer diagnóstico, estadio, progresión y actividad de una enfermedad, así como la respuesta al tratamiento. Se realizó una búsqueda de artículos publicados entre los años 1989-2013 utilizando la base de datos Medline. En el presente artículo se resumen los principales biomarcadores en asma y EPOC.

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