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>Revistas >Gaceta Médica de México >Año 2005, No. 5


Lujan-Castilla PJ, Duran-Cruz M, Enríquez-Barrera M, García-Muñóz L, Hernández-Oviedo JO, Barragán-Pérez JA
Radiocirugía estereotáxica con acelerador lineal (LINAC). Informe de la experiencia técnica en el manejo de 100 casos en el Hospital General de México
Gac Med Mex 2005; 141 (5)

Idioma: Español
Referencias bibliográficas: 49
Paginas: 367-382
Archivo PDF: 90.34 Kb.


Texto completo




RESUMEN

La radiocirugía estereotáxica consiste en la liberación de una dosis única y grande de radiación a una lesión intracraneal, pequeña, bien definida y localizada estereotáxicamente. Objetivo: El objetivo de este estudio es detallar las consideraciones técnicas y correlacionarlas con los resultados clínicos, así como reportar los márgenes de dosis utilizados. Métodos: Fueron tratados 100 pacientes mediante radiocirugía estereotáxica con LINAC. Treinta y cuatro casos de malformaciones arteriovenosas, 22 meningiomas, 18 astrocitomas, 11 adenomas hipofisiarios, 5 angiomas cavernosos, 3 neurinomas del acústico, 3 craneofaringiomas, 2 casos de epilepsia, una metástasis cerebral y un ependimoma. Las dosis de radiación utilizadas variaron en cada caso. Variables estudiadas: respuesta de la lesión, toxicidad, dosis al volumen blanco, número de isocentros, número de arcos de tratamiento, número de colimadores, dosis a órganos riesgo, homogeneidad volumen blanco, margen de error, volumen blanco, diámetro de colimadores y localización del volumen blanco. Se realizó la prueba χ2 con significancia estadística p ‹ 0.05. La media seguimiento fue de 17.7 meses. Resultados: Se presentaron tres casos de toxicidad menor. Se confirmó que a mayor volumen blanco tratado será necesario mayor número de arcos de tratamiento, con amplio margen de error y mayor número de isocentros. Conclusión: La radiocirugía es un método seguro y confiable para el manejo de entidades patológicas benignas y malignas intracraneales.


Palabras clave: Radiocirugía, neoplasias cerebrales, radiología terapéutica, celerador lineal, sistemas estereotáxicos.


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>Revistas >Gaceta Médica de México >Año2005, No. 5
 

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