medigraphic.com

2014, Número 3

Rev Med MD 2014; 5.6 (3)


Nuevas terapias antirretrovirales en la infección por VIH

González-Hernández LA, Llamas-Covarrubias MA, González-Vázquez EA, Campos-Loza AE, Arce-Rosas JI, Mercado-Nuñez E, Soria-Rodríguez R, García-Castro JA, Andrade-Villanueva JF

Idioma: Español
Referencias bibliográficas: 21
Paginas: 143-149
Archivo PDF: 1068.46 Kb.


RESUMEN

Existen alrededor de 34 millones de personas que viven con el Virus de la Inmunodeficiencia Humana (VIH) y para ellos la mejor esperanza para evitar una consecuencia fatal por la infección recae en la terapia antirretroviral (ARV), la cual consiste en la combinación de tres drogas que inhiben puntos específicos del ciclo vital del virus. El beneficio de la terapia antirretroviral en reducir la morbimortalidad es clara, sin embargo no es curativa, ya que existen células infectadas de manera latente, llamados reservorios, los cuales evitan la erradicación de la infección.
La terapia antirretroviral, ha cambiado la historia natural de la infección por el virus de inmunodeficiencia humana. En la actualidad, existen más de 20 drogas antirretrovirales las cuales han sido aprobadas por la Food and Drug Administration de Estados Unidos de Norteamérica. Aun así, debido a la aparición de cepas resistentes se encuentran en desarrollo nuevos fármacos que ofrezcan opciones para estos pacientes.


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