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>Revistas >Medicina Cutánea Ibero-Latino-Americana >Año 2003, No. 3


Londoño GAM, Hernández NDL
Enfermedad de Behçet
Med Cutan Iber Lat Am 2003; 31 (3)

Idioma: Español
Referencias bibliográficas: 96
Paginas: 149-160
Archivo PDF: 332.91 Kb.


Texto completo




RESUMEN

La enfermedad de Behçet (EB) es un desorden complejo, caracterizado por aftas orales, erupción en piel, artritis, manifestaciones oculares como uveitis, vasculitis y en algunos casos afección de sistema nervioso y grandes vasos.
Son múltiples las teorías sobre su etiopatogenia, entre las que se resaltan la presencia del HLA-B51, agentes infecciosos, disregulación inmune, daño endotelial, entre otros. Se piensa que algunos agentes infecciosos pueden disparar una respuesta por parte de las células mononucleraes y endoteliales, que en un individuo susceptible por la presencia del HLA-B51, llevaría como paso final a la generación de una respuesta inflamatoria y finalmente la vasculitis.
Los tratamientos son tan variados, como las manifestaciones clínicas, incluyen colchicina, talidomida, esteroides y agentes inmunosupresores, según la severidad del compromiso, y se requiere de un grupo interdisciplinario para llegar a un adecuado control de la enfermedad.


Palabras clave: enfermedad de Behçet, afta, uveitis.


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>Revistas >Medicina Cutánea Ibero-Latino-Americana >Año2003, No. 3
 

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