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2016, Número 1

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Gac Med Mex 2016; 152 (1)


Relación entre el ancho de distribución eritrocitaria (ADE) y la mortalidad a corto plazo en pacientes con síndrome coronario agudo (SCA)

Rosas-Cabral A, Viana-Rojas JA, Prieto-Macías J, Terrones-Saldívar MC, Gutiérrez-Campos R, Ponce-Campos SD, de Lara-Castañeda JJ

Idioma: Español
Referencias bibliográficas: 33
Paginas: 70-77
Archivo PDF: 92.71 Kb.


RESUMEN

Objetivo: Demostrar la asociación entre el ADE y el riesgo de mortalidad a corto plazo en pacientes con SCA. Método: Se clasificaron 78 pacientes con SCA según los cuartiles del ADE al ingreso hospitalario. Un ADE elevado fue definido como el valor superior al cuarto cuartil (› 15) y un ADE bajo, como el valor ubicado en los tres cuartiles inferiores (≤ 15). Tras su egreso, todos los pacientes fueron seguidos por tres meses. Resultados: La mortalidad cardiovascular a corto plazo fue del 47.2% en el grupo con ADE elevado y del 10.2% en el grupo con ADE bajo (p ‹ 0.001). En el análisis de la curva receiving operating curve (ROC), el valor de ADE elevado tuvo una sensibilidad del 66.7%, una especificidad del 83% y un valor predictivo positivo para mortalidad cardíaca del 79.7%. En el análisis multivariado, el nivel elevado de ADE fue predictor independiente de mortalidad a los tres meses (p = 0.001). Conclusiones: Se demuestra que el ADE es un parámetro accesible significativamente asociado a mortalidad cardiovascular a corto plazo en pacientes con SCA.


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