medigraphic.com
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

2016, Número 1

<< Anterior Siguiente >>

Rev Invest Clin 2016; 68 (1)


Biology of Healthy Aging and Longevity

Carmona JJ, Michan S

Idioma: Ingles.
Referencias bibliográficas: 84
Paginas: 7-16
Archivo PDF: 151.76 Kb.


RESUMEN

Sin resumen.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013;153:1194-217.

  2. Pérez VI, Buffenstein R, Masamsetti V, et al. Protein stability and resistance to oxidative stress are determinants of longevity in the longest-living rodent, the naked mole-rat. Proc Natl Acad Sci U S A. 2009;106:3059-64.

  3. Johnson TE, Cypser J, de Castro E, et al. Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors. Exp Gerontol. 2000; 35:687-94.

  4. Miller RA, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock M. Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell. 2005;4:119-25.

  5. Lin Y, Seroude L, Benzer S. Extended life-span and stress resistance in the Drosophila mutant methuselah. Science. 1998;282: 943-6.

  6. Smith ED, Kaeberlein TL, Lydum BT, et al. Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans. BMC Dev Biol. 2008;8:49.

  7. Finley LWS, Haigis MC. The coordination of nuclear and mitochondrial communication during aging and calorie restriction. Ageing Res Rev. 2009;8:173-88.

  8. Johnson T, Lithgow G. The search for the genetic basis of aging: the identification of gerontogenes in the nematode Caenorhabditis elegans. J Am Geriatr Soc. 1992;40:936-45.

  9. Salminen A, Kaarniranta K. Regulation of the aging process by autophagy. Trends Mol Med. 2009;15:217-24.

  10. Villeda SA, Luo J, Mosher KI, et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 2011;477:90-4.

  11. Egerman MA, Cadena SM, Gilbert JA, et al. GDF11 increases with age and inhibits skeletal muscle regeneration. Cell Metab. 2015; 22:164-74.

  12. Loffredo FS, Steinhauser ML, Jay SM, et al. Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy. Cell. 2013;153:828-39.

  13. Bouchard J, Villeda SA. Aging and brain rejuvenation as systemic events. J Neurochem. 2015;132:5-19.

  14. Keane M, Semeiks J, Webb AE, et al. Insights into the evolution of longevity from the bowhead whale genome. Cell Rep. 2015; 10:112-22.

  15. Treaster SB, Ridgway ID, Richardson CA, Gaspar MB, Chaudhuri AR, Austad SN. Superior proteome stability in the longest lived animal. Age (Omaha). 2013;36:1009-17.

  16. Wu Z, Song L, Liu SQQ, Huang D. A high throughput screening assay for determination of chronological lifespan of yeast. Exp Gerontol. 2011;11:915-22.

  17. Ford D, Ions LJ, Alatawi F, Wakeling LA. The potential role of epigenetic responses to diet in ageing. Proc Nutr Soc. 2011; 70:374-84.

  18. Fontana L, Partridge L. Promoting health and longevity through diet: from model organisms to humans. Cell. 2015;161:106-18.

  19. McCay C, Crowell M, Maynakd L. The effect of retarded growth upon the length of life span and upon the ultimate body size. J Nutr. 1935;10:63-79.

  20. Weindruch R. Calorie restriction and aging. Sci Am. 1996;274: 46-52.

  21. Mattison JA, Roth GS, Beasley TM, et al. Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature. 2012;489:318-21.

  22. Colman RJ, Anderson RM, Johnson SC, et al. Caloric restriction delays disease onset and mortality in rhesus monkeys. Science. 2009;325:201-4.

  23. Michan S. Calorie restriction and NAD+/sirtuin counteract the hallmarks of aging. Front Biosci. 2014;19:1300-19.

  24. Valdez G, Tapia JC, Kang H, et al. Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise. Proc Natl Acad Sci U S A. 2010;107:14863-8.

  25. Longo VD, Fontana L. Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharmacol Sci. 2010;31:89-98.

  26. Cantó C, Auwerx J. Calorie restriction: is AMPK a key sensor and effector? Physiology (Bethesda). 2011;26:214-24.

  27. Brandhorst S, Choi IY, Wei M, et al. A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan. Cell Metab. 2015;22: 86-99.

  28. Lane MA, Roth GS, Ingram DK. Caloric restriction mimetics: a novel approach for biogerontology. Methods Mol Biol. 2007; 371:143-9

  29. Venter JC, Adams MD, Myers EW, et al. The sequence of the human genome. Science. 2001;291:1304-51.

  30. Hoeijmakers JH. DNA damage, aging, and cancer. N Engl J Med. 2009;361:1475-85.

  31. Lu T, Pan Y, Kao S-Y, et al. Gene regulation and DNA damage in the ageing human brain. Nature. 2004;429:883-91.

  32. Trifunovic A, Wredenberg A, Falkenberg M, et al. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature. 2004;429:417-23.

  33. Lin J, Epel E, Blackburn E. Telomeres and lifestyle factors: roles in cellular aging. Mutat Res. 2012;730:85-9.

  34. Armanios M, Blackburn EH. The telomere syndromes. Nat Rev Genet. 2012;13:693-704.

  35. Vera E, Bernardes de Jesus B, Foronda M, Flores JM, Blasco MA. Telomerase reverse transcriptase synergizes with calorie restriction to increase health span and extend mouse longevity. PLoS One. 2013;8:e53760.

  36. Vukmirovic OG, Tilghman SM. Exploring genome space. Nature. 2000;405:820-2.

  37. Kim EB, Fang X, Fushan AA, et al. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature. 2011;479:223-7.

  38. DeBusk FL. The Hutchinson-Gilford progeria syndrome. J Pediatr. 1972;80:697-724.

  39. Ding S-LL, Shen C-YY. Model of human aging: recent findings on Werner’s and Hutchinson-Gilford progeria syndromes. Clin Interv Aging. 2008;3:431-44.

  40. Guarente L, Kenyon C. Genetic pathways that regulate ageing in model organisms. Nature. 2000;408:255-62.

  41. Tan Q, Christiansen L, von Bornemann Hjelmborg J, Christensen K. Twin methodology in epigenetic studies. J Exp Biol. 2015;218: 134-9.

  42. Carmona JJ, Sofer T, Hutchinson J, et al. Short-term airborne particulate matter exposure alters the epigenetic landscape of human genes associated with the mitogen-activated protein kinase network: a cross-sectional study. Environ Health. 2014; 13:94.

  43. Benayoun BA, Pollina EA, Brunet A. Epigenetic regulation of ageing: linking environmental inputs to genomic stability. Nat Rev Mol Cell Biol. 2015;16:593-610.

  44. Godfrey KM, Costello PM, Lillycrop KA. The developmental environment, epigenetic biomarkers and long-term health. J Dev Orig Health Dis. 2015;6:399-406.

  45. Lu T, Pan Y, Kao S-Y, et al. Gene regulation and DNA damage in the ageing human brain. Nature. 2004;429:883-91.

  46. Peters MJ, Joehanes R, Pilling LC, et al. The transcriptional landscape of age in human peripheral blood. Nat Commun. 2015;6:8570.

  47. Ng JW, Barrett LM, Wong A, Kuh D, Smith GD, Relton CL. The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities. Genome Biol. 2012;13.

  48. Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14:R115.

  49. Marioni RE, Shah S, McRae AF, et al. DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol. 2015;16-25.

  50. Taylor RC, Dillin A. Aging as an event of proteostasis collapse. Cold Spring Harb Perspect Biol. 2011;3:a00444

  51. Morimoto RI. The heat shock response: systems biology of proteotoxic stress in aging and disease. Cold Spring Harb Symp Quant Biol. 2011;76:91-9.

  52. Dokladny K, Zuhl MN, Mandell M, et al. Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy. J Biol Chem. 2013;288:14959-72.

  53. Hipp MS, Park S-H, Hartl FU. Proteostasis impairment in proteinmisfolding and -aggregation diseases. Trends Cell Biol. 2014;24: 506-14.

  54. Ori A, Toyama BH, Harris MS, et al. Integrated transcriptome and proteome analyses reveal organ-specific proteome deterioration in old rats. Cell Syst. 2015;1:224-37.

  55. Michan S. Acetylome regulation by sirtuins in the brain: from normal physiology to aging and pathology. Curr Pharm Des. 2013;19:6823-38.

  56. Schwer B, Eckersdorff M, Li Y, et al. Calorie restriction alters mitochondrial protein acetylation. Aging Cell. 2009;8:604-6.

  57. Nowotny K, Jung T, Grune T, Höhn A. Accumulation of modified proteins and aggregate formation in aging. Exp Gerontol. 2014; 57:122-31.

  58. Palacios OM, Carmona JJ, Michan S, et al. Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscle. Aging (Albany NY). 2009;1:771-83.

  59. Yang H, Yang T, Baur JA, et al. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell. 2007;130:1095-107.

  60. Burkewitz K, Zhang Y, Mair WB. AMPK at the nexus of energetics and aging. Cell Metab. 2014;20:10-25.

  61. Johnson SC, Rabinovitch PS, Kaeberlein M. mTOR is a key modulator of ageing and age-related disease. Nature. 2013;493:338-45.

  62. van Heemst D, Beekman M, Mooijaart SP, et al. Reduced insulin/ IGF-1 signalling and human longevity. Aging Cell. 2005;4:79-85.

  63. Shor B, Gibbons JJ, Abraham RT, Yu K. Targeting mTOR globally in cancer: thinking beyond rapamycin. Cell Cycle. 2009;8:3831-7.

  64. Anisimov VN, Bartke A. The key role of growth hormone-insulin- IGF-1 signaling in aging and cancer. Crit Rev Oncol Hematol. 2013;87:201-23.

  65. Michán S, Sinclair D. Sirtuins in mammals: insights into their biological function. Biochem J. 2007;404:1-13.

  66. Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature. 1993; 366:461-4.

  67. Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell. 2012;149:274-93.

  68. Harrison DE, Strong R, Sharp ZD, et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature. 2009;460:392-5.

  69. McCormick MA, Tsai SY, Kennedy BK. TOR and ageing: a complex pathway for a complex process. Philos Trans R Soc Lond B Biol Sci. 2011;366:17-27.

  70. Wu JJ, Liu J, Chen EB, et al. Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression. Cell Rep. 2013;4:913-20.

  71. Canto C, Auwerx J. Calorie Restriction: Is AMPK a key sensor and effector? Physiology. 2011;26:214-24.

  72. Greer EL, Dowlatshahi D, Banko MR, et al. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol. 2007;17:1646-56.

  73. Kaeberlein M, McVey M, Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev. 1999;13:2570-80.

  74. Michan S, Li Y, Chou MM, et al. SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci. 2010;30: 9695-707.

  75. Firestein R, Blander G, Michan S, et al. The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. PLoS One. 2008;3:e2020.

  76. North BJ, Rosenberg MA, Jeganathan KB, et al. SIRT2 induces the checkpoint kinase BubR1 to increase lifespan. EMBO J. 2014; 33:1438-53.

  77. Kanfi Y, Naiman S, Amir G, et al. The sirtuin SIRT6 regulates lifespan in male mice. Nature. 2012;483:218-21.

  78. Donmez G, Outeiro TF. SIRT1 and SIRT2: emerging targets in neurodegeneration. EMBO Mol Med. 2013;5:344-52.

  79. Zhang W-GG, Bai X-JJ, Chen X-MM. SIRT1 variants are associated with aging in a healthy Han Chinese population. Clin Chim Acta. 2010;411:1679-83.

  80. Albani D, Ateri E, Mazzuco S, et al. Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study “Treviso Longeva (TRELONG)”. Age. 2014;36:469-78.

  81. Polito L, Kehoe PG, Davin A, et al. The SIRT2 polymorphism rs10410544 and risk of Alzheimer’s disease in two Caucasian case-control cohorts. Alzheimers Dement. 2013;4:392-9.

  82. Lagouge M, Argmann C, Gerhart-Hines Z, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha. Cell. 2006;127: 1109-22.

  83. Hubbard BP, Gomes AP, Dai H, et al. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science. 2013;339:1216-9.

  84. Baur JA, Pearson KJ, Price NL, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006;444: 337-42.




2020     |     www.medigraphic.com