Pérez CR

Idioma: Español
Referencias bibliográficas: 44
Paginas: 165-169
Archivo PDF: 59.25 Kb.

RESUMEN

La hipoperfusión produce hipoxia y descenso del trifosfato de adenosina (ATP) en sepsis y choque. Simultáneamente el requerimiento de energía para la protección de las células aumenta. La restauración adecuada del volumen intravascular y la presión arterial no es suficiente para evitar el daño celular durante el periodo de hipotensión y se puede desarrollar disfunción orgánica múltiple. En este número se revisó los efectos del ATP sobre la función celular y los resultados clínicos del empleo de ésta en el tratamiento de la hipoperfusión. La ATP-Mg.Cl₂ puede incrementar el gasto cardíaco y el flujo coronario y disminuir el consumo de oxígeno sin producir hipotensión arterial.

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