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Instituto Nacional de Salud Pública

2017, Número 5

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salud publica mex 2017; 59 (5)


Micronúcleos y anormalidades nucleares en población indígena de México

Lazalde-Ramos BP, Zamora-Pérez AL, Sosa-Macías M, Galaviz-Hernández C, Zúñiga-González GM

Idioma: Ingles.
Referencias bibliográficas: 40
Paginas: 532-539
Archivo PDF: 749.76 Kb.


RESUMEN

Objetivo. Determinar el número de micronúcleos y anomalías nucleares en la población indígena de México. Material y métodos. Se evaluó a ciento veinte indígenas, incluyendo treinta individuos de las etnias cora, huichol, tarahumara y tepehuana. A cada participante se le determinó el número de micronúcleos (MN) y de alguna anomalía nuclear (AN) en células de mucosa bucal, incluyendo células con brotes nucleares, binucleadas, cariolisis, cariorrexis, cromatina condensada y picnóticas. Resultados. Los tepehuanos y tarahumaras mostraron el mayor daño al ADN. El grupo tepehuano presentó el mayor número de MN y AN, con una diferencia significativa (p ‹ 0.05) en comparación con el resto de los grupos estudiados; este grupo presentó también la mayor exposición a herbicidas (46.7%). En relación con los hábitos de fumar y beber, se presentaron con mayor frecuencia en el grupo tarahumara (33.3 y 50%, respectivamente). Conclusión. La diversidad étnica, hábitos y costumbres pueden influir la integridad del ADN en los grupos amerindios.


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