2018, Número 5
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Ann Hepatol 2018; 17 (5)
Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes
Barton JC, McLaren CE, Chen Wen-pin, Ramm GA, Anderson GJ, Powell LW, Subramaniam VN, Adams PC, Phatak PD, Gurrin LC, Phillips JD, Parker CJ, Emond MJ, McLaren GD
Idioma: Ingles.
Referencias bibliográficas: 32
Paginas: 871-879
Archivo PDF: 212.76 Kb.
RESUMEN
Sin resumen.
REFERENCIAS (EN ESTE ARTÍCULO)
Edwards CQ, Barton JC. Hemochromatosis. In: Greer JP, Arber DA, Glader B, List AF, Means Jr. RT, Paraskevas F, Rodgers GM, eds. Wintrobe’s Clinical Hematology. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins; 2014, pp. 662-81.
Bridle KR, Frazer DM, Wilkins SJ, Dixon JL, Purdie DM, Crawford DH, Subramaniam VN, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 2003; 361: 669-73.
Bacon BR, Olynyk JK, Brunt EM, Britton RS, Wolff RK. HFE genotype in patients with hemochromatosis and other liver diseases. Ann Intern Med 1999; 130: 953-62.
Barton JC, Barton JC, Acton RT, So J, Chan S, Adams PC. Increased risk of death from iron overload among 422 treated probands with HFE hemochromatosis and serum levels of ferritin greater than 1000 μg/L at diagnosis. Clin Gastroenterol Hepatol 2012; 10: 412-16.
Cheng R, Barton JC, Morrison ED, Phatak PD, Krawitt EL, Gordon SC, Kowdley KV. Differences in hepatic phenotype between hemochromatosis patients with HFE C282Y homozygosity and other HFE genotypes. J Clin Gastroenterol 2009; 43: 569-73.
Wood MJ, Powell LW, Dixon JL, Ramm GA. Clinical cofactors and hepatic fibrosis in hereditary hemochromatosis: the role of diabetes mellitus. Hepatology 2012; 56: 904-11.
Fletcher LM, Dixon JL, Purdie DM, Powell LW, Crawford DH. Excess alcohol greatly increases the prevalence of cirrhosis in hereditary hemochromatosis. Gastroenterology 2002; 122: 281-89.
Guyader D, Jacquelinet C, Moirand R, Turlin B, Mendler MH, Chaperon J, David V, et al. Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis. Gastroenterology 1998; 115: 929-36.
Barton JC, Preston BL, McDonnell SM, Rothenberg BE. Severity of iron overload in hemochromatosis: effect of volunteer blood donation before diagnosis. Transfusion 2001; 41: 123-9.
Wood MJ, Powell LW, Ramm GA. Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis. Blood 2008; 111: 4456-62.
Barton JC, Lee PL, West C, Bottomley SS. Iron overload and prolonged ingestion of iron supplements: clinical features and mutation analysis of hemochromatosis-associated genes in four cases. Am J Hematol 2006; 81: 760-7.
McLaren CE, Emond MJ, Subramaniam VN, Phatak PD, Barton JC, Adams PC, Goh JB, et al. Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload. Hepatology 2015; 62: 429-39.
Besson-Fournier C, Martinez M, Vinel JP, Aguilar-Martinez P, Coppin H, Roth MP. Further support for the association of GNPAT variant rs11558492 with severe iron overload in hemochromatosis. Hepatology 2016; 63: 2054-5.
Barton JC, Barton JC, Acton RT. Diabetes in first-degree family members: a predictor of type 2 diabetes in 159 nonscreening Alabama hemochromatosis probands with HFE C282Y homozygosity. Diabetes Care 2014; 37: 259-66.
Farrell CP, Overbey JR, Naik H, Nance D, McLaren GD, McLaren CE, Zhou L, et al. The D519G polymorphism of glyceronephosphate O-acyltransferase is a risk factor for familial porphyria cutanea tarda. PLoS One 2016; 11: e0163322.
McCormick PA. Hepatic Cirrhosis. In: Dooley JS, Lok ASF, Burroughs AK, Heathcote EJ, eds. Sherlock’s Diseases of the Liver and Biliary System. Chichester: Wiley-Blackwell; 2012, pp. 103-20.
Bowman SA, Clemens JC, Friday JE, Thoreig RC, Moshfegh AJ. Food Patterns Equivalents Database 2011-12: Methodology and User Guide [Online]. Food Surveys Research Group, Beltsville Human Nutrition Research Center, Agricultural Research Service, U S Department of Agriculture, Beltsville, Maryland. 2014.
Olynyk JK, St Pierre TG, Britton RS, Brunt EM, Bacon BR. Duration of hepatic iron exposure increases the risk of significant fibrosis in hereditary hemochromatosis: a new role for magnetic resonance imaging. Am J Gastroenterol 2005; 100: 837-41.
Loréal O, Deugnier Y, Moirand R, Lauvin L, Guyader D, Jouanolle H, Turlin B, et al. Liver fibrosis in genetic hemochromatosis. Respective roles of iron and non-iron-related factors in 127 homozygous patients. J Hepatol 1992; 16: 122-7.
Moirand R, Adams PC, Bicheler V, Brissot P, Deugnier Y. Clinical features of genetic hemochromatosis in women compared with men. Ann Intern Med 1997; 127: 105-10.
Power TE, Adams PC. Hemochromatosis patients as voluntary blood donors. Can J Gastroenterol 2004; 18: 393-6.
McDonnell SM, Grindon AJ, Preston BL, Barton JC, Edwards CQ, Adams PC. A survey of phlebotomy among persons with hemochromatosis. Transfusion 1999; 39: 651-6.
Gordeuk VR, Lovato L, Barton J, Vitolins M, McLaren G, Acton R, McLaren C, et al. Dietary iron intake and serum ferritin concentration in 213 patients homozygous for the HFE C282Y hemochromatosis mutation. Can J Gastroenterol 2012; 26: 345-9.
Wood MJ, Crawford DH, Wockner LF, Powell LW, Ramm GA. Serum ferritin concentration predicts hepatic fibrosis better than hepatic iron concentration in human HFE hemochromatosis. Liver Int 2017; 37: 1382-8.
Powell LW. The role of alcoholism in hepatic iron storage disease. Ann N Y Acad Sci 1975; 252: 124-34.
Lin E, Adams PC. Biochemical liver profile in hemochromatosis. A survey of 100 patients. J Clin Gastroenterol 1991; 13: 316-20.
Powell EE, Ali A, Clouston AD, Dixon JL, Lincoln DJ, Purdie DM, Fletcher LM, et al. Steatosis is a cofactor in liver injury in hemochromatosis. Gastroenterology 2005; 129: 1937-43.
Bassett ML, Halliday JW, Powell LW. Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis. Hepatology 1986; 6: 24-9.
Greni F, Valenti L, Mariani R, Pelloni I, Rametta R, Busti F, Ravasi G, et al. GNPAT rs11558492 is not a major modifier of iron status: study of Italian hemochromatosis patients and blood donors. Ann Hepatol 2017; 16: 451-56.
Valenti L, Maggioni P, Piperno A, Rametta R, Pelucchi S, Mariani R, Dongiovanni P, et al. Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis. World J Gastroenterol 2012; 18: 2813-20.
Stickel F, Buch S, Zoller H, Hultcrantz R, Gallati S, Osterreicher C, Finkenstedt A, et al. Evaluation of genome-wide loci of iron metabolism in hereditary hemochromatosis identifies PCSK7 as a host risk factor of liver cirrhosis. Hum Mol Genet 2014; 23: 3883-90.
Pelucchi S, Galimberti S, Greni F, Rametta R, Mariani R, Pelloni I, Girelli D, et al. Proprotein convertase 7 rs236918 associated with liver fibrosis in Italian patients with HFE-related hemochromatosis. J Gastroenterol Hepatol 2016; 31: 1342-8.