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>Revistas >Cirugía y Cirujanos >Año 2018, No. 3


López-Basave HN, Quiroz-Sandoval OA, Padilla-Rosciano AE, León-Takahashi AM, Miranda-Devora G, Arrollo-Monroy A
Papel de la cirugía citorreductora y la quimioterapia intraperitoneal hipertérmica en el tratamiento del cáncer gástrico
Cir Cir 2018; 86 (3)

Idioma: Inglés
Referencias bibliográficas: 31
Paginas: 277-284
Archivo PDF: 177.61 Kb.


Texto completo




RESUMEN

Los pacientes con carcinomatosis peritoneal (CP) de origen gástrico tienen un mal pronóstico de vida, con una supervivencia media de 1 a 3 meses. La quimioterapia sistémica ha mejorado la supervivencia de los pacientes con cáncer gástrico metastásico a los 7-10 meses. Sin embargo, este beneficio no se ha podido reproducir en los pacientes con CP. En cuanto a lo relacionado con la literatura actual para el uso de HIPEC (hyperthermic intraperitoneal chemotherapy) en la CP de origen gástrico, existe una variación significativa en la selección de pacientes, la intención de tratamiento (paliativo frente a intento de tratamiento curativo), la técnica quirúrgica, el agente quimioterapéutico intraperitoneal utilizado y la quimioterapia sistémica adyuvante administrada. Desde la perspectiva de la selección de pacientes para citorreducción y tratamiento con HIPEC, los pacientes con CP extensa no son candidatos. Además, lesiones irresecables por su localización harían al paciente un pobre candidato para citorreducción y tratamiento con HIPEC. De manera óptima, aquellos pacientes con citología peritoneal positiva en ausencia de CP son quienes más podrían beneficiarse. Sin embargo, el papel de la cirugía citorreductora y del tratamiento con HIPEC en los pacientes con CP de origen gástrico aún no ha sido esclarecido.


Palabras clave: Carcinomatosis peritoneal, Cáncer gástrico, Cirugía citorreductora, HIPEC.


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>Revistas >Cirugía y Cirujanos >Año2018, No. 3
 

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