medigraphic.com
Instituto Nacional de Salud Pública

2018, Número 6

salud publica mex 2018; 60 (6)


Prevalence and risk factors for oral human papillomavirus infection in Mexican HIV-infected men

Ablanedo-Terrazas Y, Romero-Mora K, Gómez-Palacio M, Alvarado-de la Barrera C, Ruiz-Cruz M, Hernández-Juan R, Reyes-Terán G

Idioma: Inglés.
Referencias bibliográficas: 22
Paginas: 653-657
Archivo PDF: 698.36 Kb.


RESUMEN

Objetivo. Determinar la prevalencia y los factores de riesgo para infección oral por virus de papiloma humano de alto riesgo (VPH-AR) en individuos con VIH. Material y métodos. Se incluyeron pacientes ambulatorios consecutivos con VIH. Se recabó información demográfica y sobre factores de riesgo conductuales. Se detectó DNA de VPH-AR en hisopado rectal y enjuague bucal. Se efectuó exploración de boca, faringe y videolaringoscopía para detectar lesiones. Resultados. La prevalencia de VPH-AR oral fue 9.3% (predominaron subtipos diferentes de VPH-AR 16/18). La prevalencia de VPH-AR anal fue 75.7%. Los factores de riesgo para VPH-AR oral fueron la tonsilectomía (OR=13.12) y los años de diagnóstico del VIH (OR=1.17). Conclusiones. La tonsilectomía y los años de diagnóstico del VIH se asociaron con VPH-AR oral. No hubo asociación entre VPH-AR oral y anal. Este es el primer reporte sobre prevalencia y factores de riesgo para VPH-AR oral en población mexicana con VIH.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Applebaum KM, Furniss CS, Zeka A, Posner MR, Smith JF, Bryan J, et al. Lack of association of alcohol and tobacco with HPV16-associated head and neck cancer. J Natl Cancer Inst. 2007;99:1801-10. https://doi. org/10.1093/jnci/djm233

  2. Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst. 2000;92:709-20. https://doi.org/10.1093/jnci/92.9.709

  3. Mork J, Lie AK, Glattre E, Hallmans G, Jellum E, Kiskella P, et al. Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. N Engl J Med. 2001;344:1125-31. https://doi. org/10.1056/NEJM200104123441503

  4. Chaturvedi AK, Engels EA, Pfeiffer RM, Hernandez BY, Xiao W, Kim E, et al. Human Papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol. 2011;29:4294-301. https://doi.org/10.1200/ JCO.2011.36.4596

  5. Gayar OH, Ruterbusch JJ, Elshaikh M, Cote M, Ghanem T, Hall F, et al. Oropharyngeal carcinoma in young adults: An alarming national trend. Otolaryngol Head Neck Surg. 2014;150:594-601. https://doi. org/10.1177/0194599813519738

  6. Munoz N, Bosch FX, de Sanjose S, Herrero R, Castellsagué X, Shah KV, et al. Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med. 2003;348:518-27. https://doi. org/10.1056/NEJMoa021641

  7. Maxwell JH, Grandis JR, Ferris RL. HPV-Associated head and neck cancer: Unique features of epidemiology and clinical management. Annu Rev Med. 2016;67:91-101. https://doi.org/10.1146/annurevmed- 051914-021907

  8. Kreimer AR, Alberg AJ, Daniel R, Gravitt PE, Viscidi R, Garrett ES, et al. Oral human papillomavirus infection in adults is associated with sexual behavior and HIV serostatus. J Infect Dis. 2004;189:686-98. https://doi. org/10.1086/381504

  9. Beachler DC, Abraham AG, Silverberg MJ, Beachler DC, Abraham AG, Silverberg MJ, et al. Incidence and risk factors of HPV-related and HPV-unrelated head and neck squamous cell carcinoma in HIV-infected individuals. Oral Oncol. 2014;50:1169-76. https://doi.org/10.1016/j.oraloncology. 2014.09.011

  10. Shiels MS, Cole SR, Kirk GD, Poole C. A meta-analysis of the incidence of non-AIDS cancers in HIV-infected individuals. J Acquir Immune Defic Syndr. 2009;52:611-22. https://doi.org/10.1097/QAI.0b013e3181b327ca

  11. Read TR, Hocking JS, Vodstrcil LA, Tabrizi SN, McCullough MJ, Grulich AE, et al. Oral human papillomavirus in men having sex with men: risk-factors and sampling. Plos One. 2012;7(11):e49324. https://doi.org/10.1371/ journal.pone.0049324

  12. Beachler DC, Gypsyamber D, Sugar EA, Xiao W, Gillison ML. Natural History of anal vs oral HPV infection in HIV-infected men and women. J Infect Dis. 2013;208:330-9. https://doi.org/10.1093/infdis/jit170

  13. Ong JJ, Read TR, Vodstrcil LA, Walker S, Chen M, Bradshaw CS, et al. Detection of oral Human Papillomavirus in HIV-positive men who have sex with men 3 years after baseline: A follow up cross-sectional study. Plos One. 2014;9(7):e102138. https://doi.org/10.1371/journal.pone.0102138.

  14. Hobbs CG, Groves E, Davenport V, Bailiy M, Williams NA, Birchall MA, et al. Tonsil T cell immunity to human papillomavirus in the absence of detectable virus in healthy adults. Laryngoscope. 2008;118:459-63. https:// doi.org/10.1097/MLG.0b013e31815aedb3

  15. Fakhry C, Rosenthal BT, Clark DP, Gillison ML. Associations between oral HPV16 infection and cytopathology: evaluation of an oropharyngeal “pap test equivalent” in high-risk populations. Cancer Prev Res. 2011;(4):1378-84. https://doi.org/10.1158/1940-6207.CAPR-11-0284

  16. Misiukiewicz K, Posner M. Role of prophylactic bilateral tonsillectomy as a cancer preventive strategy. Cancer Prev Res. 2015;8(5):580-2. https:// doi.org/10.1158/1940-6207.CAPR-15-0153

  17. Muller K, Kazimiroff J, Fatahzadeh M, Smith RV, Wiltz M, Polanco J, et al. Oral human papillomavirus infection and oral lesions in HIV-positive and HIV-negative dental patients. J Inf Dis. 2015;212(5):760-8. https://doi. org/10.1093/infdis/jiv080

  18. Chu FY, Lin YS, Cheng SH. Human papillomavirus infection in human immunodeficiency virus-positive Taiwanese women incarcerated for illicit drug usage. J Microbiol Immunol Infect. 2013;46(4):282-7. https://doi. org/10.1016/j.jmii.2012.06.009

  19. Read TR, Hocking JS, Vodstrcil LA, Tabrizi SN, McCullough MJ, Grulich AE, et al. Oral Human Papillomavirus in men having sex with men: Risk-factors and sampling. Plos One. 2012;7(11):e49324. https://doi. org/10.1371/journal.pone.0049324

  20. Kreimer AR, CliffordGM, Boyle P, Franceschi S. Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev. 2005;14(2):467-75. https://doi. org/10.1158/1055-9965.EPI-04-0551

  21. Stephen JK, Chen KM, Shah V. Human papillomavirus outcomes in an access-to care laryngeal cancer cohort. Otolaryngol Head Neck Surg. 2012;146:730-8. https://doi.org/10.1177/0194599811434482

  22. Centers for Disease Control and Prevention. HPV-Associated Cancers and Precancers. Sexually Transmitted Diseases Treatment Guidelines. Centers for Disease Control and Prevention, 2016 [cited 2018, January 18]. Available from: http://www.cdc.gov/std/tg2015/hpv-cancer.htm




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