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Revista Médica Sinergia

2019, Número 05

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Revista Médica Sinergia 2019; 4 (05)


Carcinoma de células de Merkel: patogénesis, manejo y tratamientos emergentes

Barquero ODE, Landaverde RDU, Segura GJM

Idioma: Español
Referencias bibliográficas: 30
Paginas: 15-23
Archivo PDF: 298.24 Kb.


RESUMEN

El carcinoma de células de Merkel es un tumor raro neuroendocrino, altamente agresivo con altas tasas de mortalidad asociadas a sus metástasis a distancia. Es más frecuente en pacientes inmunosupresos, edad avanzada y exposición a luz ultravioleta. La mayoría de asocian con Poliomavirus sin embargo existen casos sin presencia viral. Se recomienda la resección quirúrgica con márgenes extensos cuando se encuentra localizado y en casos seleccionados la biopsia de ganglio centinela. Es una neoplasia quimiosensible y radiosensible. Existen avances terapéuticos inmunológicos para casos avanzados.


REFERENCIAS (EN ESTE ARTÍCULO)

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