León CC, Rojas SR, Fuentes AF, Hernández VA

Idioma: Español
Referencias bibliográficas: 28
Paginas: 14-23
Archivo PDF: 460.41 Kb.

RESUMEN

El lupus eritematoso sistémico es una enfermedad multisistémica, prototipo de las enfermedades autoinmunes, en la que las manifestaciones hematológicas son comunes y algunas incluso forman parte de sus criterios clasificatorios. La presencia de citopenias en estos pacientes es frecuente, siendo la anemia la principal. También puede observarse leucopenia y trombocitopenia. Todas tienen múltiples etiologías, aunque comúnmente resultan de destrucción mediada inmunológicamente. En algunos casos estas manifestaciones pueden deberse a otras etiologías, como causas infecciosas o farmacológicas, por lo que es adecuado descartarlas. El manejo de cada una de estas manifestaciones depende de su respectiva etiología, en algunas la vigilancia expectante puede ser suficiente y en otras se requiere la instauración de terapia específica

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