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2000, Número 4

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Med Crit 2000; 14 (4)


Coagulación intravascular diseminada asociada a lesión cerebral grave

Carrillo ER, Hernández RA, González SJA

Idioma: Español
Referencias bibliográficas: 27
Paginas: 142-146
Archivo PDF: 105.31 Kb.


RESUMEN

Objetivo: Describir la asociación entre lesión cerebral severa y la coagulación intravascular diseminada (CID).
Diseño: Reporte de casos.
Lugar: UCI de un hospital de tercer nivel de la Ciudad de México.
Pacientes: Cuatro pacientes previamente sanos con lesión cerebral severa después de traumatismo craneoencefálico.
Intervenciones: Se administró plasma fresco congelado, crioprecipitados y plaquetas. A un paciente se le efectuó cirugía de cráneo.
Mediciones y resultados principales: Se observó trombocitopenia, alargamiento del TP, TTP y TT, hipofibrinogenemia, dímero D y productos de degradación de la fibrina elevados. Todos los pacientes murieron y el estudio post mortem mostró trombos de fibrina en los glomérulos y en la microcirculación pulmonar.
Conclusión: Los pacientes con lesión cerebral severa y CID, tienen mortalidad elevada.


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