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2003, Number 4

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Med Crit 2003; 17 (4)

HELLP syndrome, report of 52 cases in an obstetrical intensive care unit

Estrada AA,Hernández PJA,Brito BB, Vila HS, Rodríguez CS, Cisneros CM
Full text How to cite this article

Language: Spanish
References: 17
Page: 127-132
PDF size: 70.47 Kb.


Key words:

HELLP syndrome, eclampsia, clinical features, maternal complications.

ABSTRACT

Objective: To determine the clinical features of HELLP syndrome and the perinatal complications.
Design: Retrospective study.
Setting: ICU of an obstetrical and gynecological hospital of tertiary care, Mexico City.
Patients: Fifty-two patients admitted to the ICU during a two-year period were enrolled.
Interventions: None.
Measurements and main results: The incidence of HELLP syndrome was 0.69% in all births (alive). HELLP syndrome was present respectively in 39.8% and 46.15%, before and after delivery. The main obstetrics complications were: eclampsia 39.8
vs 25%, disseminated intravascular coagulation 17.8% vs 4.16%, acute renal failure 57% vs 41.7%, before and after delivery, respectively; two cases of hepatic subcapsular hematoma rupture and one case of cerebral hemorrhage were observed. Maternal mortality rate was 5.7%.
Conclusion: HELLP syndrome is a serious life-threatening complication in preeclampsia patients.



REFERENCES

  1. Barton JR, Sibai BM. Care of pregnancy complicated by HELLP syndrome. Gastroenterol Clin North Am 1992;21: 937-950.

  2. Pritchard JA, Weisman R, Rtnoff OD, Vosburgh. Intravascular hemolysis, trombocytopenia, and other hematologic abnormalities associated with severe toxemia of pregnancy. N Engl J Med 1954;250: 89-98.

  3. Curtin WM, Westein L. State of Art. A Review of HELLP Syndrome. Journal of Perinatology 1999;19:138-143.

  4. Weinstein L. Syndrome of hemolysis, elevated enzymes, and low platelet count: a severe consequence of hypertension in pregnancy. Am J Obstet Gynecol 1982;142:159-67.

  5. Dilly OC. Management of pre-eclampsia and hemolysis, elevated liver enzimes, and low platelets syndrome. Curr Obstet Ginecol 1999;11:149-53.

  6. Martin JN. The Natural history of HELLP syndrome; Patterns of disease progression and regression. Am J Obstet Gynecol 1991;164:1500-13.

  7. Sibai BM. Pregnancy outcome in 303 cases with severe preeclampsia. Obstet Gynecol 1984;64:319.

  8. Sibai BM. Pregnancies complicated by HELLP syndrome (hemolysis,elevated liver enzimes, and low platelets): Subsequent pregnancy outcome and long-term prognosis. Am J Obstet Gynecol 1995;172:125-9.

  9. Martin JN. Pregnancy complicated by preeclampsia eclampsia with the syndrome of hemolysis, elevated liver enzimes and low platelet count: How rapid is postpartum recovery? Obstet Gynecol 1990;76:737-41.

  10. Maggan EF et al. Antepartum corticosteroids: Disease stabilization in patients with the syndrome of hemolysis, elevated liver enzimes, and low platelets (HELLP). Am J Obstet Gynecol 1994;171:1148-53.

  11. Maggan EF et al. Postpartum corticosteroids: Accelerated recovery from the syndrome of hemolysis, elevated liver enzimes, and low platelets (HELLP). Am J Obstet Gynecol 1994;171: 1154-8.

  12. Martínez FJI, Aguirre AG, Coronado MH. Síndrome de HELLP-eclampsia. Rev Asoc Mex Med Crit y Ter Int 2001;XV:121-5.

  13. Martin JN. The spectrum of severe preeclampsia: Comparative analysis by HELLP (hemolysis, elevated liver enzyme levels, and low platelet count) syndrome classification. Am J Obstet Gynecol 1999;180:1373-84.

  14. Mckena J. Preeclampsia associated with hemolysis, elevated liver enzymes, and low platelets- an obstetric emergency? Obstet Gynecol 1983;62:51-4.

  15. Sibai BM. Maternal-perinatal outcome associated with the syndrome of hemolysis, elevated liver enzymes and low platelets in severe preeclampsia-eclampsia. Am J Obstet Gynecol 1986;155:501-9.

  16. National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy: Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in pregnancy. Am J Obstet Gynecol 2000;183:S1-S22.

  17. Rath W, Faridi A, Dudenhausen W. HELLP Síndrome. J Perinat Med 2000;28:249-60.




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Med Crit. 2003;17