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2021, Number 2

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Dermatología Cosmética, Médica y Quirúrgica 2021; 19 (2)

Hyaluronic Acid: Adverse Events and their Treatment. Analysis of 41 Cases in Mexico

Mora S, Espinosa S, Campos G, Gutiérrez R, Labastida O, Nava M, Navarro MA, García P, Ponce F
Full text How to cite this article

Language: Spanish
References: 17
Page: 126-131
PDF size: 221.88 Kb.


Key words:

hyaluronic acid, fillers, adverse event, complications, immediate event, early event, late event.

ABSTRACT

Introduction: the use of hyaluronic acid fillers, approved since 2004 by the American Society of Plastic Surgeons (asps), has significantly increased in recent years, becoming one of the most utilized procedures for facial rejuvenation in Latin America and Mexico. As with other cosmetic injectable procedures it is possible that complications or adverse events (AE) occur.
Objective: to identify the possible complications and adverse events that may develop from the use of these agents, as well as how are they treated in Mexico.
Methodology: a questionnaire was prepared based on the Diagnosis and Treatment of Hyaluronic Acid Adverse Event: Latin American Expert Panel Consensus Recommendations. Seven dermatologist (dermatological surgeon-oncologist), one plastic surgeon and one oculoplastic surgeon participated. Therefore, this group of physicians shared (by answering a questionnaire), data about patients who developed complications or adverse events derived from the use of hyaluronic acid fillers, as well as the treatment they received.
Results: all of the participants reported the occurrence of complications and adverse events. In this report, we show the results from the analysis of 41 case reports. Of these, 21 corresponded to immediate adverse events, 11 were early ae, and nine corresponded to late ae.
Conclusion: the use of hyaluronic acid fillers is one of the most frequent facial rejuvenation procedures in Latin America and it can present adverse events. It is crucially important to have expert physicians on the field, capable to train other physicians interested in the use of these products.


REFERENCES

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  3. Jiménez F, Hernández H y López K, Necrosis facial por aplicación de material de relleno. Un caso manejado con apósitos y fibroblastos cultivados, Dermatología cmq 2018; 16(3):222-6.

  4. Aguilar A, García P, Rebollo N, Segura G y Ruiz J, Revisión de materiales de relleno, Dermatología cmq 2015; 13(1):54-64.

  5. Signorini M, Liew S, Sundaram H, De Boulle K, Goodman G, Monheit G et al., Global aesthetics consensus: avoidance and management of complications from hyaluronic acid fillers, evidence and opinion-based review and consensus recommendations, Plast Reconstr Surg 2016; 137:961-71.

  6. Hernández A y Santana N, Enfermedad autoinmunitaria autoinflamatoria inducida por ácido hialurónico: ¿es acaso posible?, Dermatol Rev Mex 2020; 64(6):775-7.

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  8. Plastic Surgery Statistics Report, asps National Clearinghouse of Plastic Surgery Procedural Statistics, 2019.

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  16. Turkmani M, De Boulle K y Phillip W, Delayed hypersensitivity reaction to hyaluronic acid dermal filler following influenza-like illness, Clin Cosmet Invest Dermatol 2019; 12:277-83.

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Dermatología Cosmética, Médica y Quirúrgica. 2021;19