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2002, Number 4

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Bol Col Mex Urol 2002; 17 (4)

Patient's survival with renal cell carcinoma which treatment was only interferon alpha 2

Sánchez MLC, Ceballos CNE, Mendoza CE
Full text How to cite this article

Language: Spanish
References: 21
Page: 187-192
PDF size: 67.32 Kb.


Key words:

Renal cell carcinoma, metastatic, interferon.

ABSTRACT

Objective: To know the survival in patients with renal cell carcinoma. Material and methods: Transversal, retrospective, observational, descriptive and open study of the 25 patients with renal cell carcinoma between March 1997 to July 2002. We study the universal variables and we calculate the survival. Results: There were analyzed 25 files of patients with renal cell carcinoma which treatment was only interferon alpha 2. Patients 14 men (54%) and 11 women (44%) with 65 years average. Treatment with interferon was started the next year of diagnostic in 90% of the cases, the other 10% exceeded this time out any treatment. Response was complete in 3 patients (12%) and partial in 7 cases (28%); objective response was observed the four month of started the treatment, three patients survived more than 5 years despite of recurrence with interferon. Survival rate was 54%, 30%, 19%, 15%, 12% to 1, 2, 3, 4, 5 years respectively. Most of patients presented: muscle ache, fever which did not lead to abandon therapy. Conclusions: We do not find significative response. Tumor have high resistance to many forms of treatment, only three patients have a good quality of life (12%) the other patients died for local recurrence (10%) and tumoral activity to distance (90%).


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Bol Col Mex Urol. 2002;17