medigraphic.com
SPANISH

Revista Cubana de Farmacia

ISSN 1561-2988 (Print)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 3

Next >>

Rev Cubana Farm 2020; 53 (3)

Chemical, physiochemical and antifungal activity’s assessment of Bauhinia variegata L. (Fabaceae)

Pereira MFAC, Gonçalves OFJ, Martins CR, Pereira SA, Cruvinel SW, de Souza CCF
Full text How to cite this article

Language: Spanish
References: 31
Page: 1-17
PDF size: 934.64 Kb.


Key words:

Bauhinia variegata, Candida, antifungal activity, essential oils' solubility.

ABSTRACT

Introduction: Bauhinia genre is currently represented by around 300 species distributed all over the world, and a number of them with important biological actions in their extracts and essential oils. Objectives: Evaluate the chemical profile, the physicochemical characteristics and the antifungal activity of essential oils extracted from the flowers and fruits of Bauhiniavariegata over Candida genre. Methods: Flowers and fruits were collected in Rio Verde-Goiás, Brazil in the first hours of the morning. The essential oil was extracted by using the Clevenger system. Some physiochemical tests were made as organoleptic characteristics, performance (%), solubility, optical rotation, refraction index and relative density. The antifungal trial was made by using the disk diffusion method and assessing the following stumps: Candidaalbicans, C.krusei, C. tropicalis and C. guilliermondi. Results: It was proved that the essential oils are smooth and aromatic. The chemical profile showed 5 and 6 main compounds from the AEs flower and fruit, respectively. The performance was of 0,37% and 0,66%; the solubility was positive, the optical rotation was of +37,3 and +34,9 αD; the refraction index was of 1,3584 and 1,4601 in 20°C; and the relative density was of 0,937 g mL-1 and 0,931 g mL-1 in 20°C for the flower and the fruit, respectively. The results of the antifungal activity showed through the inhibition zone important results for both essential oils. All the antifungal stumps were sensitive to the assessed oily concentrations. Conclusions: The essential oils of the flower and the fruit of B. variegata show 5 and 6 main compounds, respectively, good physicochemical characteristics and special antifungal activity in comparison with the stumps of Candida. Keywords: Bauhiniavariegata; Candida; antifungal activity; essential oils´ solubility.


REFERENCES

  1. De Sousa LM, De Carvalho JL, Gois RWS, Da Silva HC, Santiago GMP, Lemos TLG, et al. Chemical composition, larvicidal and cytotoxic activities of the essential oils from two Bauhinia species. Records of Natural Products. 2016;10(3):341-8. DOI: 10.1016/j.sajb.2020.03.011

  2. Simões RC, De Almeida SSMS. Estudo fitoquímico de Bauhinia forficata (Fabaceae). Biota Amazônia. 2015;5(1):27-31. DOI: 10.18561/2179-5746/biotaamazonia.v5n1p27-31

  3. Arain S, Memon N, Rajput MT, Sherazi STH, Bhanger MI, Mahesar AS. Physico-chemical characteristics of oil and seed residues of Bauhinia variegata and Bauhinia linnaei. Pakistan Journal of Analytical & Environmental Chemistry. 2012 [acceso 10/09/2020];13(1):16-21. Disponible en: http://www.pjaec.pk/index.php/pjaec/article/view/199

  4. Negi A, Ghildiyal P, Suyal J, Dobhal K, Semwal A. Pharmacognostical studies and preliminary phytochemical investigation on the bark of Bauhinia variegata (Caesalpiniaceaea). International Journal of Research in AYUSH and Pharmaceutical Sciences. 2017 [acesso 10/09/2020];1(4):155-161. Disponible en: https://1library.net/document/yd99x81z-pharmacognostical-studies-preliminary-phytochemical-investigation-bauhinia-variegata-caesalpiniaceaea.html

  5. Da Silva KLC, Da Silva MMC, De Moraes MM, Da Camara CAG, Dos Santos ML, Fagg CW. Chemical composition and acaricidal activity of essential oils from two species of the genus Bauhinia that occur in the Cerrado biome in Brazil. Journal of Essential oil Research. 2020;32(1):23-31. DOI: 10.1080/10412905.2019.1662338

  6. Nogueira ACO, Sabino CVS. Revisão do gênero Bauhinia abordando aspectos científicos das espécies Bauhinia forficata Link e Bauhinia variegata L. de interesse para a indústria farmacêutica. Revista Fitos. 2012 [acceso 10/09/2020];7(2):77-84. Disponible en: https://www.arca.fiocruz.br/handle/icict/19201

  7. Menezes Filho ACP, De Sousa WC, Castro CFS. Atividades antioxidante e antifúngica dos óleos essenciais de Cochlospermum regium frente à Sclerotinia sclerotiorum e Colletotrichum gloeosporioides. Colloquium Agrariae. 2020;16(1):109-116. DOI: 10.5747/ca.2020.v16.n1.a353

  8. Duarte-Almeida JM, Negri G, Salatino A. Volatile oils in leaves of Bauhinia (Fabaceae Caesalpinioideae). Biochemical and Systematics Ecology. 2004;32(8):747-753. DOI: 10.1016/j.bse.2004.01.003

  9. Wassel GM, Abdel Wahab SM, Ammar NM. Constituents of the essential oils from Bauhinia variegata L. and Bauhinia purpurea L. flowers. Scientia Pharmaceutica. 1986;54:357-359.

  10. De Sousa LM, De Carvalho JL, Gois RWS, Da Silva HC, Santiago GMP, Lemos TLG, et al. Chemical composition, larvicidal and cytotoxic activities of the essential oils from two Bauhinia species. Records of Natural Products. 2016;10(3):341-8. DOI: 10.1016/j.sajb.2020.03.011

  11. Colombo AL, Guimarães T. Epidemiologia das infecções hematogênicas por Candida spp. Revista da Sociedade Brasileira de Medicina Tropical. 2003;36(5):599-607. DOI: 10.1590/S0037-86822003000500010

  12. Takahashi Possatto J, Melhem MSC. Uso de fungicidas na agricultura e resistência a antifúngicos na clínica médica. Boletim do Instituto Adolfo Lutz. 2014 [acceso 10/09/2020];24(1):40-41. Disponible en: https://www.escavador.com/sobre/5113470/juliana-possatto-takahashi

  13. Fait ME, Bakas L, Garrote GL, Morcelle SR, Saparrat MCN. Cationic surfactants as antifungal agents. Applied Microbiology and Biotechnology. 2019;103:97-112. DOI: 10.1007/s00253-018-9467-6

  14. Torrenegra Alarcón ME, Granados Conde C, León Méndez G. Extraccíon, caracterización y actividad antioxidante del aceite esencial de Eucalyptus globulus Labill. Revista Cubana de Farmacia. 2019 [acceso 10/09/2020];52(1):e266. Disponible en: http://revfarmacia.sld.cu/index.php/far/article/view/266/206

  15. Noriega Rivera P, Paredes EA, Díaz Gómez E, Lueckhoff A, Almeida GA, Suarez SE. Composición química y actividad antimicrobiana del aceite esencial de los rizomas de Renealmia thyrsoidea (Ruiz & Pav) Poepp. & Eddl. (shiwanku muyu). Revista Cubana de Plantas Medicinales. 2017 [acceso 10/09/2020];22(2). Disponible en: http://www.revplantasmedicinales.sld.cu/index.php/pla/article/view/505

  16. Sharma N, Bhardwaj R, Singh B, Kaur S. Essential oil composition of Bauhinia variegata L. flowers. World Journal of Pharmacy and Pharmaceutical Sciences. 2013; 2(5):3604-11. [acceso 10/09/2020] Disponible en: https://www.semanticscholar.org/paper/ESSENTIAL-OIL-COMPOSITION-OF-BAUHINIA-VARIEGATA-L.-Sharma-Bhardwaj/c10b51cb9930ce5b269baa7857b695aacc86cc13?p2df

  17. Sahoo D, Ahmad A, Ahamd J, Tandon S. Chemical composition of the essential oil from flowers of Bauhinia variegata (Kachnar) of Northern India. Journal of Essential Oil Bearing Plants. 2013;16(5):636-640. DOI: 10.1080/0972060X.2013.854503

  18. León Méndez G, Osorio Fortich MR, Torrenegra ME, Gil Gónzalez J. Extraction, characterization and antioxidant activity of essential oil from Plectranthus amboinicus L. Rev Cubana Farm. 2015 [acceso 10/09/2020];49(4):708-718. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75152015000400011&lng=es

  19. Gomes PRB, Silva ALS, Mouchrek VE, Mouchrek NA, Everton PC. Avaliação físico-química do óleo essencial Zingiber officinale Roscoe (Gengibre). Revista Cubana de Farmacia. 2017 [acceso 1009/2020];50(2). Disponible en: http://www.revfarmacia.sld.cu/index.php/far/article/view/30/34

  20. Santos TC, Rebelo RA, Dalmarco EM, Guedes A, Gasper AL, Cruz AB, et al. Composição química e avaliação da atividade antimicrobiana do óleo essencial das folhas de Piper malacophyllum (C. Presl.) C. DC. Química Nova. 2012;35(3):477-81. DOI: 10.1590/S0100-40422012000300007

  21. Granados Conde C, Yáñez Rueda X, , Santafe Patiño GG. Evaluación de la actividad antioxidante del aceite esencial foliar de Calycolpus moritzianus y Minthostachys mollis de Norte de Santander. Bistua: Revista de La Facultad de Ciencias Básicas. 2012 [acceso 10/09/2020];10(1):12-23. Disponible en: https://www.redalyc.org/pdf/903/90326398005.pdf

  22. Torrenegra M, Granados C, Osorio M, León G. Method comparison of hydrodistillation microwave radiation-assisted (MWHD) front hydrodistillation (HD) in the extraction of essential oil of Minthostachys mollis. Journal of Information Technology. 2015;26(1):117-122. DOI: 10.4067/S0718-07642015000100013

  23. El-Moula AKFG, Awad AE, El-Sayed AI, El-Saadany SS. Antibacterial activity of water and ethanolic extracts of Bauhinia variegata leaves. Biotechnology Research. Zagazig Journal of Agriculture Research. 2019;46(4):1141-48. DOI: 10.21608/ZJAR.2019.47096

  24. Mishra A, Sharma AK, Kumar S, Saxena AK, Pandey AK. Bauhinia variegata leaf extracts exhibit considerable antibacterial, antioxidant, and anticancer activities. BioMed Research International. 2013;2013:1-10. DOI: 10.1155/2013/915436

  25. Sharma AK, Sharma UK, Pandey AK. Protective effect of Bauhinia variegata leaf extracts against oxidative damage, cell proliferation and bacterial growth. Proceedings of the National Academy of Sciences. 2017;87(1):45-51. DOI: 10.1155/2013/915436

  26. Filho VC. Chemical composition and biological potential of plants from the genus Bauhinia. Phytotherapy Research. 2009;23:1347-54. DOI: 10.1002/ptr.2756

  27. Achenbach H, Stocker M, Constenla MA. 1988. Flavonoid and others constituents of Bauhinia manca. Phytochemistry. 1988;27:1835-41. DOI: 10.1016/0031-9422(88)80455-2

  28. Gunalan G, Saraswathyl A, Krishnamurthy V. Antimicrobial activity of medicinal plant Bauhinia variegata Linn. International Journal of Pharmacy and Biological Sciences. 2011 [acceso 10/09/2020];1(4):400-8. Disponible en: http://www.ijpbsonline.com/uploads/1/2/1/8/12183777/400-408.pdf

  29. Nagumanthri V, Rahiman S, Tantry BA, Nissankararao P, Kumar MP. In vitro antimicrobial activity of Acacia nilotica, Ziziphus mauritiana, Bauhinia variegata and Lantana camara against some clinical isolated strains. Iranian Journal of Science & Technology. 2012;A2:213-7. DOI: 10.22099/IJSTS.2012.2070

  30. Rashid KI, Ahmmed SJ, Mahmood-Mukhtar ZF. Study the antibacterial activity of Bauhinia variegata Linn. plant leaf extracts against some species of pathogenic bacteria. Journal of Al-Nahrin University. 2014;17(1):55-9. DOI: 10.22401/JNUS.17.1.21

  31. Mishra NP, Verma A. Evaluation of antimicrobial, antifungal and phytochemical properties of Bauhinia variegata. Current Research in Pharmaceutical Sciences. 2014;4(2):57-63. DOI: 10.24092




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Cubana Farm. 2020;53