Pabón-Moreno A, Gaitán-Quintero GA, Beltrán-Carrascal EJ, Ortiz-Henao EF

Language: Spanish
References: 12
Page: 613-618
PDF size: 281.54 Kb.

ABSTRACT

Background: The postrema area syndrome is included in neuromyelitis optica spectrum disorders, which contain a heterogeneous group of autoimmune and demyelinating inflammatory disorders of the central nervous system, associated frequently with the specific water channel antibody of aquaporin-4 (AQP4). The postrema area syndrome is characterized by intractable nausea, vomiting and hiccups without any apparent cause. The postrema area is a circumventricular organ with abundant AQP4 located on the floor of the fourth ventricle with multiple connections to structures of the brainstem and hypothalamus; with important physiological functions in the control of vomiting reflex, appetite and blood pressure, among others.
Clinical case: A 32-year-old female patient with postrema area syndrome, who started with intractable hiccups associated with the AQP4 antibody.
Conclusions: The postrema area syndrome is a manifestation of the neuromyelitis optica spectrum disorders with a higher incidence in the adult population; it should be suspected in the presence of intractable emesis or hiccups that persist for more than 48 hours without a probable cause.

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