2017, Number 3
Design of a system for the management and statistical processing of genetic databases in Cuba
Full text
Language: Spanish
References: 5
Page: 25-31
PDF size: 555.82 Kb.
ABSTRACT
The research carried out by the National Center for Medical Genetics of Cuba in the last ten years has generated records with information on tens of thousands of people and families all over the country. The individuals included in the medical records have genetic diseases, congenital defects, or participate in research even without suffering a specific disease, as is the case of twin pairs. The dispersion of the registered data and the lack of computer tools to manage them have conditioned the lack of obtaining maximum benefit from the processing of this information, which must be used to benefit the health system itself. In the present work we propose the design and implementation of a system that integrates and allows to manage, filter, analyze and graph the set of data previously exposed. Finally, tests are carried out to verify their efficiency and functioning and recommendations are proposed to increase their extensibility.REFERENCES
Marcheco-Teruel, Beatriz, Esteban J Parra, Evelyn Fuentes-Smith, Antonio Salas, Henriette N Buttenschøn, Ditte Demontis, María TorresEspañol, Lilia C Marín-Padrón, Enrique J Gómez-Cabezas, Vanesa Álvarez-Iglesias y cols.: Cuba: exploring the history of admixture and the genetic basis of pigmentation using autosomal and uniparental markers. PLoS Genet, 10(7):e1004488, 2014.
World Medical Association Declaration of Helsinki. Ethical principles for medical research involving human subjects. World Medical Association. Clinical Review & Education [en línea]. 2013 [citado 1 de septiembre de 2017]. Disponible en: http://www.up.ac.za/media/shared/Legacy/sitefiles/file/45/2875/declarationofhelsinki_fortaleza_brazil2013.pdf