García ACB, Guzmán PMG

Language: Spanish
References: 9
Page: s69-72
PDF size: 193.08 Kb.

ABSTRACT

During last 10 months, the association of urticaria with or without angioedema with COVID-19 has been documented. We describe four patients with urticaria and SARS-CoV-2. Two of them had a positive PCR test for SARS-CoV-2, one developed IgG antibodies and another even though the antibody test was negative, he had symptoms compatible with COVID-19, an acute inflammatory systemic syndrome and a family member positive for COVID-19. They were successfully treated with second and third generation antihistamines with complete resolution of the urticaria. Urticaria can precede or be concomitant to the classic COVID-19 symptoms. In hospitalized patients with moderate to severe disease and multiple treatments, drugs should be in the differential diagnosis as the possible cause of the urticaria.

REFERENCES

1. Freeman EE, McMahon DE, Lipoff JB, Rosenbach M, Kovarik C, Desai SR et al. The spectrum of COVID-19 associated dermatologic manifestations: an international registry of 716 patients from 31 countries. J Am Acad Dermatol. 2020; 83: 1118-1129. doi: 10.1016/j.jaad.2020.06.1016.

2. Galván CC, Català A, Carretero HG, Rodríguez-Jiménez P, Fernández-Nieto D, Rodríguez-Villa LA et al. Classification of the cutaneous manifestation of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. 2020; 183 (1): 71-77. doi: 10.1111 / bjd.19163.

3. Algaadi SA. Urticaria and COVID-19: a review. Dermatol Ther. 2020; 33 (6): e14290. doi: 10.1111 / dth.14290.

4. Najafzadeh M, Shahzad F, Ghaderi N, Ansari K, Jacob B, Wright A. Urticaria (angioedema) and COVID-19 infection. J Eur Acad Dermatol Venereol. 2020; 34: e568-e570. doi: 10.1111/jdv.16721.

5. Rodriguez-Jimenez P, Chicharro P, De Argila D, Muñoz-Hernández M, Llamas-Velasco. Urticaria-like lesions in COVID-19 patients are not really urticaria - a case with clinicopathological correlation. J Eur Acad Dermatol Venereol. 2020; 34: e459-e460. doi: 10.1111/jdv.16618.

6. Wollina U, Kardag AS, Rowland-Payne C, Chiriac A, Lotti T. Cutaneous signs in COVID-19 patients: a review. Dermatol Ther. 2020; 33 (5): e13549. doi: 10.1111 / dth.13549.

7. Van Damme C, Berlingin E, Saussez S, Accaputo O. Acute urticaria with pyrexia as the first manifestations of a COVID-19 infection. J Eur Acad Dermatol Venereol. 2020; 34: e300-e301. doi: 10.1111/jdv.16523.

8. Gisondi P, Plaserico S, Bordin C, Alaibac M, Girolomoni G, Naldi L. Cutaneous manifestations of SARS-CoV-2 infection: a clinical update. J Eur Acad Dermatol Venereol. 2020; 34 (11): 2499-2504. doi: 10.111/jdv.16774.

9. De Perosanz-Lobo D, Fernandez-Nieto D, Burgos-Blasco P, Selda-Enriquez G, Carretero I, Fernández-Guarino M. Urticarial vasculitis in COVID-19 infection: a vasculopathy-related symptom? J Am Acad Dermatol. 2020; 34 (10): e566-e568. doi: 10.1111/jdv.16713.