2020, Number 4
<< Back Next >>
Rev Mex Cir Endoscop 2020; 21 (4)
Results of abdominal cavity lavages with neutral electrolyzed water in patients with acute abdomen approached by laparoscopic surgery compared to physiological saline solution lavages or no lavages
Valdés PJO, Gutiérrez HLR, López CJ, Ruiz MG, Rosa BA, Benítez TA, Mervitch SN, Cabrera LA
Language: Spanish
References: 14
Page: 191-199
PDF size: 219.03 Kb.
ABSTRACT
Introduction: Neutral electrolyzed water (SES) is a well-recognized broad-spectrum antiseptic that does not cause tissue damage. This work explored whether peritoneal lavages with neutral electrolyzed water during laparoscopic procedures, in patients with acute surgical abdomen admitted to the National Homeopathic Hospital in Mexico City, offers advantages over lavages with normal saline solution, or over intervening without lavages.
Material and methods: A retrospective cohort study was carried out where development of postoperative complications and length of hospital stay were compared between groups without peritoneal lavages, lavages with normal saline solution, and those with electrolyzed water, with 0.002% of active chlorine and oxygen species. Data were analyzed with two-tailed ANOVA and odds ratio tests.
Results: No patient lavaged with SES developed postsurgical difficulties, and this was significant with respect to not lavage [OR = 0.02343 (95% CI 0.001286-0.4268)] or lavage with physiological saline solution [OR = 0.05051 (95% CI 0.002632-0.9690)]. The group lavaged with SES showed greater significance in the reduction of days of hospital stay (1.61 ± 0.76) than the group lavaged with physiological saline solution (2.40 ± 1.14) or the group without lavages (2.36 ± 1.46).
Conclusions: A positive association was found between peritoneal lavages during laparoscopic surgery and a lower incidence of both postoperative complications and length of hospital stay, which was more significant with electrolyzed water than with physiological solution, while no lavages was associated with a greater number of patients with postoperative complications and longer hospital stay.
REFERENCES
Gorordo-Delsol L, Pérez-Nieto OR, Porras-Escorcia O, Altamirano-Arcos CA. Sepsis abdominal: fisiopatología, diagnóstico y tratamiento. Rev Mex Cirugía del Apar Dig. 2015; 4: 110-117.
Zhang W, Zheng Y, Feng X, Chen M, Kang Y. Systemic inflammatory response syndrome in sepsis-3: A retrospective study. BMC Infect Dis. 2019; 19: 139.
Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med. 2017; 43: 304-377.
Hajibandeh S, Hajibandeh S, Kelly A, Shah J, Khan RMA, Panda N et al. Irrigation versus suction alone in laparoscopic appendectomy: Is dilution the solution to pollution? A systematic review and meta-analysis. Surg Innov. 2018; 25: 174-182.
Edmiston CE, Leaper DJ. Intra-operative surgical irrigation of the surgical incision: what does the future hold - saline, antibiotic agents, or antiseptic agents? Surg Infect. 2016; 17: 656-564.
Singal R, Dhar S, Zaman M, Singh B, Sing V, Sethi S. Comparative evaluation of intra-operative peritoneal lavage with super oxidized solution and normal saline in peritonitis cases; randomized controlled trial. Maedica. 2016; 11: 277-285.
Khan S, Verma A, Shahid M, Khan M. Evaluation of pre-operative peritoneal lavage by super-oxidized solution in peritonitis. Middle East J Intern Med. 2009; 2: 15-35.
Garg P, Garg A, Kumar A, Saini A, Sandhu A, Sharda V. Evaluation of intraoperative peritoneal lavage with super-oxidized solution and normal saline in acute peritonitis. Arch Int Surg. 2013; 3: 43-48.
Nachón GFJ, Díaz TJ, Benítez OF, García GF, Santiago GJ, Martínez CAJ. Lavado peritoneal transoperatorio con solución electrolizada por selectividad iónica en peritonitis secundaria. Cir Gen. 2010; 32: 11-16.
Szumilas M. Explaining odds ratios. J Can Acad Child Adolesc Psychiatry. 2010; 19: 227-229.
GraphPad Prism versión 6.0 para Windows. GraphPad Software, La Jolla, California USA.
Holmstrom KM, Finkel T. Cellular mechanisms and physiological consequences of redox-dependent signalling. Nat Rev Mol Cell Biol. 2014; 15: 411-421.
Sun F, Wang H, Zhang F, Zhang X, Xing Z, Zhang S et al. Copious irrigation versus suction alone during laparoscopic appendectomy for complicated appendicitis in adults. J Investig Surg. 2018; 31: 342-346.
Kim HJ, Nkufi TC, Chelliah R, Oh DH. Sanitization Efficacy of Slightly Acidic Electrolyzed Water against pure cultures of Escherichia coli, Salmonella enterica, Typhimurium, Staphylococcus aureus and Bacillus cereus spores, in comparison with different water hardness. Sci Rep. 2019; 9: 1-14.