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Anales de Otorrinolaringología Mexicana

2021, Number 3

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Otorrinolaringología 2021; 66 (3)

Moderately differentiated neuroendocrine carcinoma of the nasal cavity

Busto-Ruano JP, Reyes-Ortega LM, Romo-Magdaleno JA, Mora-Mendoza I, de Luna-Sánchez MP, Alanís-Núñez AJ, Sánchez-Santa Ana JR

Language: Spanish
References: 10
Page: 233-239
PDF size: 244.70 Kb.


ABSTRACT

Background: Carcinomas with neuroendocrine differentiation are tumors that occur extraordinarily in the nose and sinuses, representing only 5% of all sinonasal malignancies. They are considered primitive tumors and are the least differentiated of the diffuse neuroendocrine system. These types of tumors are a diagnostic challenge due to their complexity to differentiate them in a histopathological study. Likewise, there are no clear available guidelines, and the result of treatment continues to be variable and poor.
Clinical case: A 49-year-old female patient diagnosed with moderately differentiated neuroendocrine carcinoma successfully managed by total resection with an endoscopic endonasal approach.
Conclusions: The effective differentiation of these tumors can have a clinical impact, so advances in therapeutic intervention could prolong patient survival, improve quality of life and even achieve a cure.


REFERENCES

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