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Anales de Otorrinolaringología Mexicana

2021, Number 3

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Otorrinolaringología 2021; 66 (3)

Nasosinusal glomangiopericytoma

Plata-Sánchez JA

Language: Spanish
References: 20
Page: 240-244
PDF size: 256.00 Kb.


ABSTRACT

Background: Glomangiopericytoma is a mesenchymal neoplasm derived from the Zimmerman pericytes described by Stout and Murray in 1942. The most frequent presentation is in the pelvic limbs followed by the abdominal cavity and the retroperitoneum. It is considered a low-grade, slow-growing sarcoma, with a malignancy frequency of 15-20%. The presentation in the head and neck is 15-30% and of these, only 5% is located at the sinonasal level. It occurs in middle-aged patients, affecting both sexes equally. The calculated survival is 80% at 5 years. Its etiology is unknown. Clinically, it presents as a pale, painless, slow-growing mass that leads to unilateral nasal obstruction, hyaline rhinorrhea, and occasionally epistaxis. Its diagnosis is made by histopathological and immunohistochemical study. Differential diagnoses include solitary fibrous tumor, leiomyoma, leiomyosarcoma, angiofibroma, synovial sarcoma, malignant schwannoma, etc. The treatment of choice is surgical excision with lesion-free margins.
Clinical case: A 63-year-old female patient with a long-standing tumor in the right nostril, with an initial diagnosis by biopsy and immunohistochemistry of Ewing’s sarcoma that after surgical management was diagnosed as nasosinusal glomangiopericytoma.
Conclusions: Glomangiopericytoma is an infrequent tumor of mesenchymal origin and extremely rare at the nasosinusal level, with slow growth and nonspecific clinical manifestations that make its suspicion difficult.


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