medigraphic.com
SPANISH

Revista Cubana de Medicina Militar

ISSN 1561-3046 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 3

<< Back Next >>

Rev Cub Med Mil 2020; 49 (3)

Clinical characterization of obstetric patients with suspected COVID-19

Segura FAB, León CI, Urgellés CSA, Ramos ZV, Herrera FY, Rodríguez CC, Caballero MY, Silvente CA, Duménigo RCA, Acosta León O
Full text How to cite this article

Language: Spanish
References: 22
Page:
PDF size: 229.11 Kb.


Key words:

coronavirus infections, COVID-19, pregnancy, SARS-CoV-2.

ABSTRACT

Introduction: The COVID-19 pandemic has caused more than 350,000 deaths worldwide.
Objective: To clinically characterize obstetric patients with suspected COVID-19.
Methods: A retrospective, descriptive, cross-sectional study was performed. All obstetric patients admitted to the Hospital Militar Central "Dr. Luis Díaz Soto" between March 12 and May 20, 2020. They were divided into two groups; Group I included those with negative RT-PCR for SARS-CoV-2 and group II with positive results. The variables analyzed were age, obstetric history, personal pathological history, epidemiological history, clinical picture, complications, admission to the intensive care unit and maternal mortality.
Results: 60 obstetric patients were admitted and 6 (10%) were positive for SARS-CoV-2, from the provinces of Havana, Mayabeque and Artemisa. The average age was 25 years. 25.9% of group I and 66.6% of group II were in the 1st trimester of pregnancy. 38.8% and 16.6%, of group I and group II, respectively, presented comorbidity. 50% of the positives were asymptomatic. Leukopenia was observed in 10 (18.5%) cases in group I and in 5 (83.3%) in group II. Spontaneous abortion occurred in group II. There was no COVID-19 pneumonia, nor maternal death.
Conclusions: COVID-19 occurred more frequently in pregnant women during the first trimester, the mild form of the disease prevailed, with no COVID-19 pneumonia or deaths from this disease.


REFERENCES

  1. Zhu N, Zhang D, Wang W, Li X, Yang B, J Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020 [acceso: 23/05/2020]; 382(8):727-33. Disponible en: https://www.nejm.org/doi/pdf/10.1056/NEJMoa2001017

  2. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet. 2020 [acceso: 23/05/2020]; 395(10223):497-506. Disponible en: https://doi.org/10.1016/S0140-6736(20)30183- 5

  3. Redacción médica. Sanitaria 2000. Jesús Arroyo.[actualizado: 11/03/2020; acceso: 23/05/2020]. Coronavirus: la OMS declara la pandemia a nivel mundial por Covid-19. Adhanom T(1), Disponible en: https://www.redaccionmedica.com/secciones/sanidad-hoy/coronavirus-pandemia-brote-de-covid-19-nivel-mundial-segun-oms-1895

  4. Sitio web oficial del Ministerio de Salud Pública de Cuba. Cuba: ARCHIVO DIARIO. [actualizado: 20/05/2020; acceso: 23/05/2020]. COVID-19. Disponible en: https://salud.msp.gob.cu/?m=20200520

  5. Armas L. Día a día: COVID-19 en Cuba. Cuba mayo 2020 [acceso: 23/05/2020]. Disponible en: https://www.cubahora.cu/blogs/datos-con-sentido/dia-a-dia-covid-19-en-cuba

  6. Rothan H A, Byrareddy S N. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. Journal of Autoimmunity. 2020 [acceso: 23/05/2020]; 109(102433):13. Disponible en: https://doi.org/10.1016/j.jaut.2020.102433

  7. Manual MSD. Tesini BL. Mayo 2020 [actualizado: 05/2020; acceso: 23/05/2020]. Coronavirus y síndromes respiratorios agudos (COVID-19, MERS y SARS) (7). Disponible en: https://www.msdmanuals.com/es/professional/enfermedades-infecciosas/virus-respiratorios/coronavirus-y-s%C3%ADndromes-respiratorios-agudos-covid-19-mers-y-sars?query=Coronavirus%20y%20s%C3%ADndromes%20respirato-rios%20agudos%20(COVID-19,%20MERS%20y%20SARS)

  8. Guan W, Ni Z, Hu Y, Liang, W, Ou C, J. He, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med. 2020 [acceso: 23/05/2020]; 382(18):1708-1720. Disponible en: https://www.nejm.org/doi/full/10.1056/NEJMoa2002032

  9. Ojeda JJ, Rodríguez M, Estepa JL, Piña CN, Cabeza BL. Cambios fisiológicos durante el embarazo. Su importancia para el anestesiólogo MediSur. 2011[acceso: 23/05/2020]; 9(5):67-74. Disponible en: https://www.redalyc.org/pdf/1800/180022343011.pdf

  10. Siston AM, Rasmussen SA, Honein MA, Fry AM, Seib K, Callaghan WM, et al. Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States. JAMA. 2010 [acceso: 23/05/2020];303(15):1517-25. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823273/

  11. Dashraath P, Jeslyn JL, Karen MX, Choolani M, Mattar C, Su LL. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol. 2020 [acceso: 23/05/2020]; 222(6):521-531. Disponible en: https://www.ajog.org/article/S0002-9378(20)30343-4/fulltext

  12. Mizumoto K, Kagaya K, Zarebski A, Chowell G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill. 2020 [acceso: 23/05/2020]; 25(10):2000180. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078829/

  13. Sutton D, Fuchs K, D'Alton M, Goffman D. Universal Screening for SARS-CoV-2 in Women Admitted for Delivery. N Engl J Med. 2020 [acceso: 23/05/2020]; 382(22):2163-2164. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175422/

  14. Khalil A, Hill R, Ladhani S, Pattisson K, O'Brien P. SARS-CoV-2 in pregnancy: symptomatic pregnant women are only the tip of the iceberg. Am J Obstet Gynecol. 2020 [acceso: 23/05/2020]; 6:S0002-9378(20)30529-9. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204681/

  15. Yan J, Guo J, Fan C, Juan J, Yu X, Li J, et al. Coronavirus disease 2019 (COVID-19) in pregnant women: A report based on 116 cases, American Journal of Obstetrics and Gynecology. 2020 [acceso: 23/05/2020]; 223(1):111.e1-111.e14. Disponible en: https://www.sciencedirect.com/science/article/pii/S0002937820304622

  16. Donders F, Lonnée-Hoffmann R, Tsiakalos A, Mendling W, Martinez de Oliveira J, Judlin P, Xue F, Donders GG. ISIDOG COVID-19 Guideline Workgroup. ISIDOG Recommendations Concerning COVID-19 and Pregnancy. Diagnostics. 2020 [acceso: 23/05/2020];10(4):243. Disponible en: https://www.mdpi.com/2075-4418/10/4/243/htm

  17. Schwartz DA. An Analysis of 38 Pregnant Women with COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes. Archives of Pathology & Laboratory Medicine. 2020 [acceso: 23/05/2020]; 144:799-805 Disponible en: https://europepmc.org/article/med/32180426

  18. Nunzia A, Rizzo R, Pilu G, Simonazzi G. Coronavirus disease 2019 during pregnancy: a systematic review of reported cases. American Journal of Obstetrics and Gynecology.2020 [acceso: 23/05/2020]; 223(1):36-41. Disponible en: https://www.ajog.org/article/S0002-9378(20)30438-5/fulltext

  19. Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, Xia S, Zhou W. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020 [acceso: 23/05/2020]; 9(1):51-60. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036645/

  20. World Health Organization. Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). WHO. 2020 [acceso: 23/05/2020]. Disponible en: https://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19---final-report-1100hr-28feb2020-11mar-update.pdf?sfvrsn=1a13fda0_2&download=true

  21. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet. 2020[acceso: 23/05/2020]; 395(10226):809-815. Disponible en: https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(20)30360-3.pdf

  22. Ramos MM, Soligo ML, Borges E. Maternal deaths with coronavirus disease 2019: a different outcome from low- to middle-resource countries? Am J Obstet Gynecol. 2020 [acceso: 23/05/2020]; S0002-9378(20):30471-3. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195009/




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Cub Med Mil . 2020;49