Valdés TRM, Hernández EML

Language: Spanish
References: 9
Page:
PDF size: 297.27 Kb.

ABSTRACT

Introduction: Aspergillosis is an opportunistic fungal infection that occurs mainly in immunosuppressed patients and its main source of transmission is the spores present in the air of operating rooms and intensive care units.
Objective: To present a case of a massive pulmonary mycosis due to an angioinvasive variant of Aspergillus.
Clinical case: A patient with severe pulmonary aspergillosis, diagnosed after resection of a mediastinal tumor, is presented. The characteristics of the first intervention are described, the postoperative evolution that led to the second one, the tomographic, surgical, microbiological and anatomo-pathological images that allowed to define the diagnosis are shown.
Conclusions: The possibility of a pulmonary mycosis should be taken into account, even when it is a rare and difficult-to-handle condition, in immunocompromised patients, with pulmonary condensation that is rebellious to treatment. Aspergillosis is an opportunistic fungal infection that occurs mainly in immunosuppressed patients and its main source of transmission is the spores present in the air of operating rooms and intensive care units.

REFERENCES

1. Patterson TF. Aspergillus species. En: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's. Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014. p. 259.

2. Borges M. Profilaxis antifúngica en UCI. En: Jordá R, editor. Medicina crítica práctica: tratamiento antifúngico en el paciente grave. 4.ª ed. Barcelona: Edikamed; 2017. p. 121-33.

3. Liebana A. Presentaciones clínicas de la aspergilosis nosocomial. Rev Iberoamericana Micología. 2000[acceso: 08/05/2019];17(22):85-9. Disponible en: https://reviberoammicol.com/2000-17/S85S89.pdf

4. Tellado JM, Sitges-Sierra A, Barcenilla F, Palomar M, Serrano R, Barberán J, et al. Pautas del tratamiento antibiotico empirico de las infecciones intraabdominales. Rev. Esp. Quimioterap. 2005[acceso: 08/05/2019];18(2):179-86. Disponible en: http://www.dep4.san.gva.es/contenidos/urg/archivos/guias/2005/infecciones%20intraabdominales%20(Consenso%202005).pdf

5. Walsh TJ. Aspergillosis. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016. p 339.

6. Budpa P, Dive A, Sibille Y. Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease. Eur Respir J. 2007[acceso: 08/05/2019];30:782-800. Disponible en: https://erj.ersjournals.com/content/30/4/782.short

7. Messer SA, Jones RN, Fritsche TR. International surveillance of Candida spp. and Aspergillus spp.: report from the SENTRY Antimicrobial Surveillance Program (2003). J Clin Microbiol. 2006[acceso: 10/05/2019];44(5):1782-7. Disponible en: https://jcm.asm.org/content/44/5/1782

8. Meersseman W, Vandecasteele SJ, Wilmer A, Verbeken E, Peetermans WE, Van Wijngaerden E. Invasive aspergillosis in critically ill patients without malignancy. Am J Respir Crit Care Med. 2004[acceso: 10/05/2019];170(6):621-5. Disponible en: https://www.atsjournals.org/doi/full/10.1164/rccm.200401-093OC

9. Saraceno JL, Phelps DT, Ferro TJ, Futerfas R, Schwartz DB. Chronic necrotizing aspergillosis: Approach to management.Rev Iberoam Micol.1997[acceso: 10/05/2019]; 112(2):541-48. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0012369215530316