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2020, Number 4

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Rev Cub Med Mil 2020; 49 (4)

Clinical prognostic factors determining the survival of patients with the Ebola virus

Miranda GO, Castro BCM, Fleites AYA, Díaz GJE, Contreras OY, Urgellés CSA

Language: Spanish
References: 19
Page:
PDF size: 314.76 Kb.


ABSTRACT

Introduction: Ebola virus disease has a high lethality, which is why it is of great interest to carry out research that addresses clinical manifestations that could be prognostic factors for survival.
Objective: To evaluate prognostic factors of Ebola patients.
Methods: the universe was constituted by the totality (n = 350) of admitted patients. Summary measures were used for qualitative variables, point and interval estimates for quantitative variables, as well as Kaplan-Meier significance tests, Cox regression and Odds Ratio. We worked with a 95% level of reliability.
Results: The overall survival was 42.5%. The average survival, approximately 10 days (CI: 9-11 days). Patients who were admitted in serious condition (OR = 3.76), who had low back pain (OR = 2.24), who reported headache (OR = 2.22), who presented fever (OR = 2.16), who they suffered from abdominal pain (OR = 1.95) and who were found to have conjunctival injection (OR = 1.86), were more likely to die than those who entered without these symptoms and signs.
Conclusions: Survival was high, despite the complications presented. The symptoms and predictive signs of death in the patients were: the severity of the patient at admission, the presence of low back pain, headache, fever, abdominal pain and conjunctival injection.


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