Gómez-Márquez JJ, Estrada-Medrano A, Polendo-Villarreal JA, Martínez-Elizondo SG, Sepúlveda-Oyervides VM

Language: Spanish
References: 10
Page: 209-214
PDF size: 87.93 Kb.

ABSTRACT

Objective: To assess the use of epidural morphine after prosthetic surgery of the hip and knee, in order to address the need for effective and safe analgesia. Materials and methods: Fifty patients were divided into two groups: Group A (study group, n = 25), Group B (control group, n = 25). A mixed blockade was applied in both groups, administering 12.5 mg bupivacaine in the subarachnoid space and placing an inert epidural catheter. After the surgical procedure was finished, Group A was given 2 mg morphine in 8 ml water through the epidural catheter. Intravenous metamizole sodium, 35 mg/kg/24 hours in three divided doses, could be used as rescue analgesia. Group B was given intravenous metamizole, 35 mg/kg/24 hours in three divided doses. Nalbuphine, 0.075 mg/kg/dose, could be used as rescue analgesia. The same visual and verbal scale were used in both groups. Nausea, emesis, pruritus, urinary retention and ventilatory depression were assessed as safety parameters. Variance analysis of the scales was used as a statistical tool. Results: There were no differences among groups in demographic data and adverse events. Pain scales in both groups showed differences among baseline values and those recorded later on. Statistic analysis demonstrated better analgesia and less use of rescue analgesia in group A. Conclusions: Epidural morphine was effective for the control of postoperative pain, but not statistically superior. Rescue analgesia was needed in both groups.

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