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2004, Number s2

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Arch Cardiol Mex 2004; 74 (s2)

Myocardial hypertrophy as an adaptative mechanism and as a pathological process

Guadalajara BJF
Full text How to cite this article

Language: Spanish
References: 36
Page: 442-454
PDF size: 257.03 Kb.


Key words:

Adequate hypertrophy, Inadequate hypertrophy, Inappropriate hypertrophy.

ABSTRACT

Myocardial hypertrophy is an adaptative mechanism that allows systolic parietal stress to normalize when the heart has to contract against a higher normal pressure (systolic overload), or the diastolic stress when the normal diastolic volume is higher (diastolic overload). That allows the heart to maintain a normal cardiac waste before such hemodynamic overloads. When neurohumoral mechanisms (adrenergic and renin-angiotensin-aldosterone system) are activated by any reason, myocardial interstice augments its collagen tissue and that causes diastolic dysfunction, myocardial ischemia and cardiac failure.


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Arch Cardiol Mex. 2004;74