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Revista Cubana de Oftalmología

ISSN 1561-3070 (Electronic)
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2020, Number 3

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Rev Cub Oftal 2020; 33 (3)

Therapeutic use of hyaluronidase and triamcinolone in orbital pseudotumor

Garduño-Vieyra L, Castro-Camacho E, De la Fuente-Batta I, Lira-Álvarez A
Full text How to cite this article

Language: Spanish
References: 10
Page: 1-7
PDF size: 337.22 Kb.


Key words:

orbital pseudotumor, hyaluronidase, triamcinolone, exophthalmometry, papilledema.

ABSTRACT

The exact etiology of orbital pseudotumor is unknown, but its granulomatous unspecific inflammatory nature at various locations has been recognized. Orbital pseudotumor is defined as a cellular pleomorphic inflammatory response of limited evolution often confined to orbital structures. A case is presented of a female 16-year-old patient diagnosed with orbital pseudotumor confirmed by biopsy and computerized axial tomography, refractory to treatment with systemic steroids, due to which it is decided to start treatment with hyaluronidase and triamcinolone in the peribulbar space. Acute cases often respond fast to treatment with corticosteroids such as prednisone. It should be borne in mind that there are patients who are refractory to treatment for whom alternative treatments should be sought. An option is the use of hyaluronidase to destroy extracellular junctions and locally spread a steroid such as triamcinolone, most effectively within the inflammatory tissue to ensure its localized effect. Total regression of the patient's status was observed at three months of treatment.


REFERENCES

  1. Dina J, Steven G. Diagnosis and management of orbital pseudotumor. Curr Op Ophthalmol. 2002;13(6):357-1.

  2. Gegúndez JA. Diferentes formas clínicas de pseudotumor orbitario. Stud Ophthalmol. 1999;18(2):117-21.

  3. Hamad-Cueto O, Tamayo Toledo JA, Márcol-Parod AA, et al. Sídrome de Tolosa-Hunt y pseudotumor orbitario: entidades solapadas en un caso con perfil clínico no habitual. Rev Neurol. 2006;42:530-4.

  4. Mora-de-Oñate J, Pérez-Alfaro PP. Oftalmoplejia dolorosa (pseudotumor y síndrome de Tolosa-Hunt). Ach Soc Esp Oftalmol. 2007;82(8):509-12.

  5. American Academy of Ophthalmology (BCSC): Orbit, eyelids and lacrimal System. 2015-2016. San Francisco: American Academy of Ophtlalmology; 2015.

  6. Leivovitch I, Prabhakaran V. Intraorbital injection of triamcinolone acetonide in patients UIT idiopathic orbital inflammation. Arch Ophtalmol. 2007;125(12):1647-51.

  7. Mombaerts I, Schlingemann RO, Goldschmeding R. Are systemic corticosteroids useful in the management of orbital pseudotumors? Ophthalmology. 1996;103(3):521-8.

  8. Ebner R, Devoto MH, Weil D. Treatment of thyroid associated ophthalmopathy with periocular injections of triamcinolone. Br J Ophthalmol. 2004;88(11):1380-6.

  9. Goldber RA. Orbital steroid injections. Br J Ophtalmol. 2004;88(11):1359-60.

  10. Bardenstein DS. Idiopathic orbital inflammation: Distribution, Clinical feautures and Treatment Outcome. Ophthalmol Clin North Am. 1996;9(4):659-72.




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Rev Cub Oftal. 2020;33