Mendoza-Aldaba II, Fortoul TI

Language: Spanish
References: 19
Page: 46-54
PDF size: 341.90 Kb.

ABSTRACT

Air pollution is continuously present as its sources have increased. In the season of high insolation, scarce wind, and lack of rain there is an increase in the signs and symptoms of high concentrations of pollution, mainly there is an increase in respiratory symptoms, but little has been reported from the eye, which is directly exposed to the environment. Dry eye syndrome (SOS) is defined as “a multifactorial disease of the tears and ocular surface that results in symptoms of ocular discomfort, impaired vision and instability of the tear film with potential damage to the ocular surface”.
Around 5 to 34% of the world population suffers from SOS and the prevalence increases with age, being more frequent in women (2:1). Risk factors include hormonal changes, nutritional deficiencies, air pollution, dyslipidemia and obesity. Environmental factors such as decrease in atmospheric humidity, prolonged exposure to screens, air purity, extreme temperatures, UV radiation and high levels of particulate matter (PM) participate in the same way.
SOS is a multifactorial disorder. It is divided into 2 groups: “dry eye with poor tear production (aqueous-deficient)” and “dry eye with increased evaporation of the tear film (hyperevaporative)” and the mixture of both types, hyperevaporative/ deficient aqueous, are more than 80% of the cases. The most frequently reported symptom is a foreign body sensation. They also report burning, itching, excessive mucus secretion, not being able to secrete a tear, burning sensation, photosensitivity, red eye, pain, and blurred vision. The diagnosis of SOS is made by the clinical history, physical examination and symptoms reported by the patient. Treatment requires proper diagnosis of the cause and to decrease the different components that cause the symptoms. It is important to apply treatments that reduce the dysfunction of the meibomian glands, which are a relevant component in the pathophysiology of this disease.

REFERENCES

1. Messmer EM. The pathophysiology, diagnosis, and treatment of dry eye disease. Dtsch Arztebl Int. 2015;112(5):71- 81; quiz 2.

2. Choi HR, Kim NH, Lee JM, Choi DP, Seo Y, Cho WK, et al. Risk Factors Influencing the Occurrence and Severity of Symptomatic Dry Eye Syndrome: A Cross-sectional Study. Ophthalmic Epidemiol. 2021:1-7.

3. Goyal S, Chauhan SK, El Annan J, Nallasamy N, Zhang Q, Dana R. Evidence of corneal lymphangiogenesis in dry eye disease: a potential link to adaptive immunity? Arch Ophthalmol. 2010;128(7):819-24.

4. Lemp MA. Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. CLAO J. 1995;21(4):221-32.

5. Yu D, Deng Q, Wang J, Chang X, Wang S, Yang R, et al. Air Pollutants are associated with Dry Eye Disease in Urban Ophthalmic Outpatients: a Prevalence Study in China. J Transl Med. 2019;17(1):46.

6. Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, et al. TFOS DEWS II Epidemiology Report. Ocul Surf. 2017;15(3):334-65.

7. Alves M, Novaes P, Morraye Mde A, Reinach PS, Rocha EM. Is dry eye an environmental disease? Arq Bras Oftalmol. 2014;77(3):193-200.

8. Cervantes-Yepez S, Lopez-Zepeda LS, Fortoul TI. Vanadium inhalation induces retinal Muller glial cell (MGC) alterations in a murine model. Cutan Ocul Toxicol. 2018;37(2):200-6.

9. Mandell JT, Idarraga M, Kumar N, Galor A. Impact of Air Pollution and Weather on Dry Eye. J Clin Med. 2020;9(11).

10. Lee H, Kim EK, Kang SW, Kim JH, Hwang HJ, Kim TI. Effects of ozone exposure on the ocular surface. Free Radic Biol Med. 2013;63:78-89.

11. Song SJ, Hyun SW, Lee TG, Park B, Jo K, Kim CS. New application for assessment of dry eye syndrome induced by particulate matter exposure. Ecotoxicol Environ Saf. 2020;205:111125.

12. Moshirfar M, West WB, Jr., Marx DP. Face Mask-Associated Ocular Irritation and Dryness. Ophthalmol Ther. 2020;9(3):397-400.

13. Thomas J, Jacob GP, Abraham L, Noushad B. The effect of smoking on the ocular surface and the precorneal tear film. Australas Med J. 2012;5(4):221-6.

14. Shtein RN, Jacobs DS, J G. Dry Eye Disease. Uptodate. 2020.

15. Baudouin C, Messmer EM, Aragona P, Geerling G, Akova YA, Benitez-del-Castillo J, et al. Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction. Br J Ophthalmol. 2016;100(3):300-6.

16. Aragona P, Giannaccare G, Mencucci R, Rubino P, Cantera E, Rolando M. Modern approach to the treatment of dry eye, a complex multifactorial disease: a P.I.C.A.S.S.O. board review. Br J Ophthalmol. 2021;105(4):446-53.

17. Lee H, Kim M, Park SY, Kim EK, Seo KY, Kim TI. Mechanical meibomian gland squeezing combined with eyelid scrubs and warm compresses for the treatment of meibomian gland dysfunction. Clin Exp Optom. 2017;100(6):598-602.

18. Marta A, Baptista PM, Heitor Marques J, Almeida D, Jose D, Sousa P, et al. Intense Pulsed Plus Low-Level Light Therapy in Meibomian Gland Dysfunction. Clin Ophthalmol. 2021;15:2803-11.

19. Godin MR, Stinnett SS, Gupta PK. Outcomes of Thermal Pulsation Treatment for Dry Eye Syndrome in Patients With Sjogren Disease. Cornea. 2018;37(9):1155-8.