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Órgano Oficial del Instituto Nacional de Pediatría
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2021, Number 5

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Acta Pediatr Mex 2021; 42 (5)

Lipschutz ulcers and Campylobacter jejuni: report of two cases

Delgado-Martín MV, Cano de Santayana-Domínguez ME, Feito-Caldas C
Full text How to cite this article

Language: Spanish
References: 8
Page: 247-250
PDF size: 560.27 Kb.


Key words:

Lipschütz ulcers, Vulvar diseases, Painful, Adolescent girls, Epstein Barr virus, Campylobacter Jejuni, Hospitalization, Pain management, Antibiotic treatment.

ABSTRACT

Background: Cases of Lipschutz ulcers are rare, necrotic in appearance, very painful and rapidly progressive. They mainly affect sexually inactive adolescent girls. Although they are usually associated with a primoinfection by Epstein Barr virus or other pathogens, in most cases the infectious agent is not isolated.
Objective: To report two cases and to disseminate the possible association of Lipschütz ulcers with the infectious agent Campylobacter jejuni, even in recurrences.
Clinical case: Pediatric patients aged 10 and 12 years in whom painful genital ulcers appeared in the context of fever and diarrhea and were diagnosed as Lipschütz ulcers. The stool culture isolated Campylobacter jejuni as a concomitant pathogen. In the 12-year-old patient there was a recurrence of ulcers, one year after the first episode that required hospitalization for pain control, with a very good response to the first dose of steroids. In both cases the evolution was satisfactory with disappearance of the lesions in a few weeks, without the need for antibiotic treatment, despite bacterial growth in the stool culture.
Conclusions: Despite their low frequency, Lipschütz ulcers should be kept in mind in the differential diagnosis of genital ulcers, especially in patients who have not become sexually active, and the coexistence of Campylobacter jejuni, among other pathogens, should be investigated.


REFERENCES

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  2. Jerdan K, Aronson I, Hernandez C, Fishman PM, Groth JV. Úlceras genitales asociadas con el virus de Epstein-Barr. Cutis 2013; 91 (6): 273-6.

  3. Lorenzo CV, Robertson WS. Genital ulcerations as presenting symptom of infectious mononucleosis. J Am Board Fam Pract 2005; 18 (1): 67-8. https://pubmed.ncbi.nlm. nih.gov/15709067/

  4. Luque-González P, Azcona-Sutil L, Vargas-Gálvez D, Carmona Domínguez E, Barroso-Tudela C, Cabezas-Palacios M. Úlcera de Lipschütz: reporte de un caso y revisión bibliográfica. Ginecol Obstet Mex 2020; 88 (9): 644-50. https://doi.org/10.24245/gom.v8819.4102

  5. Rosman IS, Berk DR, Bayliss SJ. Úlceras genitales agudas en nińas jóvenes no sexualmente activas: serie de casos, revisión de la literatura y recomendaciones de evaluación y manejo. Pediatr Dermatol 2012; 29: 147-53. https://doi. org/10.1111/j.1525-1470.2011.01589.x

  6. Arellano J, Fuentes L, Moreno P, Corredoira Y. Úlcera de Lipschütz, un diagnóstico para considerar en la población pediátrica. Arch Argent Pediatr 2019; 117 (3): 305-8. doi: 10.5546/aap.2019.e305.

  7. Hueto Najarro A, González García G, Breton Hernández P, Zarate Tejero I, Lanuza Arcos R, Ferrer Santos P. Úlceras genitales de Lipschütz: reporte de un caso pediátrico. Arch Argent Pediatr 2017; 115 (6): 436-39. doi: 10.5546/ aap.2017.e436.

  8. Díaz López L, Pavía Lafuente M, Vázquez Olaiz MC, Pascual Díez L, Arluziaga Gondat M, Puente-Campano Fernández LE. Úlcera de Lipschütz con evolución tórpida a sinequia vulvar. Acta Pediátrica Espańola 2016; 74 (8) e186-e188




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C?MO CITAR (Vancouver)

Acta Pediatr Mex. 2021;42