Martínez ÁTG, Elizalde FF, Delgado CM, Cañas LL, Limón AJL, Pinto SME

Language: Spanish
References: 11
Page: 491-496
PDF size: 160.39 Kb.

ABSTRACT

Introduction: Recently the objectives of major surgery have been a focus on offering the best possibilities that lead to a fast recovery and the return of the patient to his daily task, and this must be carried with adequate analgesic quality, this matter represents a challenge for the anesthesiologist choosing which drug to use during the trans-anesthetic period. Material and methods: This is a study of case and control type, 26 patients were studied any type of major noncardiac surgery under balanced general anesthesia, with the aim of quantifying the consumption of intraoperative fentanyl, In a homogeneous population, it was determined that there is lower consumption of trans anesthetic opioids in the group that was perfused with dexmedetomidine with a value of p < 0.05, as well as a better analgesic quality, this last one was measured using the numerical scale of pain. Results: Thus, concluding that the use of dexmedetomidine as an infusion during the trans anesthetic period reduces the consumption of opioids and probably contributes to a faster recovery.

REFERENCES

1. Scott MJ, Baldini G, Fearon KC, Feldheiser A, Feldman S, Gan TJ et al. Enhanced recovery after surgery (ERAS) for gastrointestinal surgery, part 1: pathophysiological considerations. Acta Anaesthesiol Scand. 2015; 59: 1212-1231.

2. Rudd RA, Seth P, David F, Scholl L. Increases in drug and opioid involved overdose deaths in United States. MMWR Morb Mortal Wkly Rep. 2016; 65 (50): 1445-1452.

3. Mantz J, Josserand J, Hamada S. Dexmedetomidine: new insights. Eur J Anaesthesiol. 2011; 28 (1): 3-6.

4. Chavan SG, Shinde GP, Adivarekar SP, Gujar SH, Mandhyan S. Effects of dexmedetomidine on perioperative monitoring parameters and recovery in patients undergoing laparoscopic cholecystectomy. Anesth Essays Res. 2016; 10 (2): 278-283.

5. Mugabure B, González S, Uría A, Conejero G, González N. Coadyuvantes farmacológicos con efecto ahorrador de opioides en el periodo perioperatorio. Rev Soc Esp Dolor. 2018; 25(5): 278-290.

6. Weerink M, Struys M, Hannivoort L, Barends C, Absalom A, Colin P. Clinical pharmacokinetics and pharmacodynamics of dexmedetomidine. Clin Pharmacokinet. 2017; 56 (8): 893-913.

7. Afonso J, Reis F. Dexmedetomidine: current role in anesthesia and intensive care. Rev Bras Anestesiol. 2012; 62 (1): 118-133.

8. Egan TD. Are opioids indispensable for general anaesthesia? Br J Anaesth. 2019; 122 (6): e127-e135.

9. Jaschinski T, Mosch CG, Eikermann M, Neugebauer EAM, Sauerland S. Laparoscopic versus open surgery for suspected appendicitis. Cochrane Database Syst Rev. 2018; 11 (11): CD001546.

10. Mohammad MZ, Mahsa KF, Maryam SF, Armin HM, Nima R, Amir B et al. Survival benefits of dexmedetomidine used for sedating septic patients in intensive care setting: a systematic review. J Crit Care. 2016; 32: 93-100.

11. Ke W, Shiying H, Jun D. Dexmedetomidine in pediatric intravenous general anesthesia without tracheal intubation. Int J Clin Exp Med. 2018; 11 (5): 4891-4897.