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2021, Number 4

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Acta Med 2021; 19 (4)

Incidence of SARS-CoV-2 infection in three fertility clinics in Mexico

Ulloa MMÁ, García JG, Espino SS, Rojas PS, Lorenzo BC, Martínez PL, Escobedo BL

Language: Spanish
References: 14
Page: 514-518
PDF size: 153.45 Kb.


ABSTRACT

Introduction: During the COVID-19 pandemic, the impact of the virus in pregnant patients was gradually studied, which caused a delay in the desire of some mothers to achieve conception. Objectives: To describe the incidence of SARS-CoV-2 virus infection in fertility centers in Mexico City. Material and methods: It is a descriptive, cross-sectional, observational, retrospective study, carried out in three assisted reproduction clinics in Mexico City. Egg donor women and candidates for assisted reproduction procedures who underwent the SARS-CoV-2 PCR test were included. Results: A sample of 50 patients was obtained, 84% with infertility and 16% ovodonators with a mean age of 35.4 ± 6.25 years. 55% with advanced maternal age, 59.5% with primary infertility, and 40.5% secondary, predominating as comorbidity hypothyroidism. Four patients were found with positive CRP for SARS-CoV-2 (p = 0.041), three in contact with positive people (p = 0.003) and with symptoms in the last 15 days (p = 0.371). Conclusions: The incidence of SARS-CoV-2 infection in fertility centers is significantly low. Assisted reproduction procedures should not be delayed, always seeking the maximum health protection measures, towards patients and the staff of fertility centers.


REFERENCES

  1. Vaiarelli A, Bulletti C, Cimadomo D, Borini A, Alviggi C, Ajossa S et al. COVID-19 and ART: the view of the Italian Society of Fertility and Sterility and Reproductive Medicine. Reprod Biomed Online [Internet]. 2020; 40 (6): 755-759. Available in: http://dx.doi.org/10.1016/j.rbmo.2020.04.003

  2. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y et al. Early transmission dynamics in wuhan, china, of novel coronavirus-infected pneumonia. N Engl J Med [Internet]. 2020; 382 (13): 1199-1207. Available in: http://dx.doi.org/10.1056/NEJMoa2001316

  3. Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR et al. The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application. Ann Intern Med [Internet]. 2020; 172 (9): 577-582. Available in: http://dx.doi.org/10.7326/M20-0504

  4. COVID-19 UNAM-Mexico [Internet]. [Cited June 19, 2020]. Available in: https://covid19.ciga.unam.mx/

  5. Albertini DF. Buffering reproductive science in the era of COVID-19. J Assist Reprod Genet [Internet]. 2020; 37 (5): 1017. Available in: http://dx.doi.org/10.1007/s10815-020-01824-4

  6. Fan C, Lei D, Fang C, Li C, Wang M, Liu Y et al. Perinatal Transmission of 2019 Coronavirus Disease–Associated Severe Acute Respiratory Syndrome Coronavirus 2: Should We Worry? Clinical Infectious Diseases. 2020; 72 (5): 862-864.

  7. Alviggi C, Esteves SC, Orvieto R, Conforti A, La Marca A, Fischer R et al. COVID-19 and assisted reproductive technology services: repercussions for patients and proposal for individualized clinical management. Reprod Biol Endocrinol [Internet]. 2020; 18 (1): 45. Available in: http://dx.doi.org/10.1186/s12958-020-00605-z

  8. Esteves SC, Carvalho JF, Bento FC, Santos J. A novel predictive model to estimate the number of mature oocytes required for obtaining at least one euploid blastocyst for transfer in couples undergoing in vitro fertilization/intracytoplasmic sperm injection: the ART calculator. Front Endocrinol (Lausanne) [Internet]. 2019; 10: 99. Available in: http://dx.doi.org/10.3389/fendo.2019.00099

  9. Poseidon Group (Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number), Alviggi C, Andersen CY, Buehler K, Conforti A, De Placido G et al. A new more detailed stratification of low responders to ovarian stimulation: from a poor ovarian response to a low prognosis concept. Fertil Steril [Internet]. 2016; 105 (6): 1452-1453. Available in: http://dx.doi.org/10.1016/j.fertnstert.2016.02.005

  10. Diccionario de Cáncer del NCI [Internet]. 2011 [citado el 26 de octubre de 2020]. Disponible en: https://www.cancer.gov/espanol/publicaciones/diccionario

  11. Rasmussen SA, Lyerly AD, Jamieson DJ. Delaying pregnancy during a public health crisis - examining public health recommendations for Covid-19 and beyond. N Engl J Med [Internet]. 2020; 383 (22): 2097-2099. Available in: http://dx.doi.org/10.1056/NEJMp2027940

  12. Ben-Kimhy R, Youngster M, Medina-Artom TR, Avraham S, Gat I, Haham LM et al. Fertility patients under COVID-19: attitudes, perceptions, and psychological reactions. Hum Reprod [Internet]. 2020; 35 (12): 2774-2783. Available in: http://dx.doi.org/10.1093/humrep/deaa248

  13. Boivin J, Harrison C, Mathur R, Burns G, Pericleous-Smith A, Gameiro S. Patient experiences of fertility clinic closure during the COVID-19 pandemic: appraisals, coping and emotions. Hum Reprod [Internet]. 2020; 35 (11): 2556-2566. Available in: http://dx.doi.org/10.1093/humrep/deaa218

  14. Mo Y, Wan R, Zhang Q. Application of reverse transcription-PCR and real-time PCR in nanotoxicity research. Methods Mol Biol [Internet]. 2012; 926: 99-112. Available in: http://dx.doi.org/10.1007/978-1-62703-002-1_7




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