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2020, Number 4

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Rev Cubana Plant Med 2020; 25 (4)

Antibacterial activity of extract of Mentha arvensis L. (field mint) against strains causing pyodermitis

González HRM, Romero MV, Delgado MM, Martínez AY, González HLJ

Language: Spanish
References: 24
Page:
PDF size: 122.14 Kb.


ABSTRACT

Introduction: Use of plants to cure disease dates back to thousands of years ago. Plants have been used either in their natural form or to develop new drugs with the support of results obtained by pharmacological research. Increase in the incidence of infections of viral etiology and resistance to conventional antimicrobials have led to the search for new treatment alternatives. Mentha arvensis L. has been attributed analgesic, antiemetic, antirheumatic and antiseptic properties. However, no evidence is available of its in vitro activity against multiresistant clinical strains (penicillin, ampicillin, cefoxitin, cefalexin) causing bacterial skin infection.
Objective: Evaluate the minimum inhibitory concentration and minimum bactericidal concentration of an extract of Mentha arvensis L. (field mint) against strains causing bacterial skin infection.
Methods: The fluid extract was obtained by repercolation. Determination was made of the minimum inhibitory and bactericidal concentration against strains of Staphylococcus aureus and Pseudomonas aeruginosa isolated from skin lesions, using the tube macrodilution method. The groups of secondary metabolites responsible for antibacterial activity were determined by qualitative phytochemical screening.
Results: Phytochemical screening revealed the presence of coumarins, flavonoids, tannins and terpenes, all of which are secondary metabolites responsible for antibacterial activity. Minimum inhibitory concentration and minimum bactericidal concentration of Mentha arvensis L. (field mint) were 12.5 μl/ml and 12.5 μl/ml, respectively, against Staphylococcus aureus, and 12.5 μl/ml and 50 μl/ml, respectively, against Pseudomona aeruginosa.
Conclusions: Evidence was found of the presence of terpenoids, flavonoids and coumarins. The study extract displayed antibacterial activity against wild strains of Staphylococcus aureus and Pseudomonas aeruginosa. It is recommended to use ATCC strains for comparison and to gain insight in future research.


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