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Revista Mexicana de Pediatría

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2021, Number 4

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Rev Mex Pediatr 2021; 88 (4)

Miller Fisher Syndrome: An uncommon Guillain Barré variant

Morales-Galindo AL, Bolaños-Aparicio LF
Full text How to cite this article 10.35366/102779

DOI

DOI: 10.35366/102779
URL: https://dx.doi.org/10.35366/102779

Language: Spanish
References: 8
Page: 149-151
PDF size: 209.28 Kb.


Key words:

Miller Fisher, Guillain Barré, ophthalmoplegia, ataxia, poly-radiculoneuropathy, neuroconduction.

ABSTRACT

Objective: We present the clinical case of a 10-year-old patient with a diagnosis of Miller Fisher syndrome, a variant of Guillain Barré syndrome, which is rare in children. Case description: Ophthalmoplegia, diplopia, muscle weakness, and ataxia was the patient's clinical picture. Diagnosis of Miller Fisher syndrome was made based on the clinical data, the presence of albumin-cytological dissociation in the cerebrospinal fluid, and the report of an electroneurographic study with abnormal motor neuronconduction and polyradiculoneuropathy of the axonal type. The patient received intravenous immune gamma globulin showing improvement in symptoms. Conclusion: The clinical picture should guide the suspicion of Miller Fisher syndrome, but studies should be carried out to confirm the diagnosis, in order to offer treatment as soon as possible.


REFERENCES

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  2. Jiménez-Domínguez R, Montante-Montes-De A, Martínez-Mata J, Cruz-Fino D, Ruíz-Franco A, Ramírez-Hernández M et al. Síndrome de Miller Fisher, una variante del síndrome de Guillain Barré. Rev Mex Neuroci. 2009; 10(5): 367-370.

  3. Sánchez-Torrent L, Noguera-Julian A, Pérez-Dueñas B, Nascimento-Osorio A, Colomer-Oferil J. Síndrome de Miller Fisher en la edad pediátrica: descripción de 3 casos. An Pediatr (Barc). 2009; 71(4): 377-378.

  4. Govoni V, Granieri E, Tola MR, Casseta I, Ruppi P, Vaghi L. The frequency of clinical variants of Guillain-Barré syndrome in Ferrara, Italy. J Neurol. 1999; 246: 1010-1014.

  5. Bassal F, Lupo P. Case 3: Ophthalmoplegia and Unsteady Gait in an 11-year-old Boy. Pediatr Rev. 2018; 39(1): 39.

  6. Muñiz AE. Multiple cranial nerve neuropathies, ataxia and, areflexia: Miller Fisher syndrome in a child and review. Am J Emerg Med. 2017; 35(4): 661.e1-661.e4.

  7. De Pablos C, Calleja J, Fernández F, Berciano J. Miller Fisher syndrome: an electrophysiologic case study. Electromyogr Clin Neurophysiol. 1988; 28(1): 21-25.

  8. Mori M, Kuwabara S, Fukutake T, Hattori T. Intravenous immunoglobulin therapy for Miller Fisher syndrome. Neurology. 2007; 68(14): 1144-1146.




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C?MO CITAR (Vancouver)

Rev Mex Pediatr. 2021;88