medigraphic.com
SPANISH

Revista Cubana de Urología

ISSN 2305-7939 (Electronic)
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2020, Number 3

<< Back Next >>

RCU 2020; 9 (3)

Infrequent infectious agents affecting seminal parameters and fertility

Pacheco L, Lozano-Hernández R, Velasco J
Full text How to cite this article

Language: Spanish
References: 50
Page: 128-142
PDF size: 1185.70 Kb.


Key words:

seminal infection, accessory glands, male infertility, bacteriospermia.

ABSTRACT

Introduction: Bacteriological research of semen is fundamental for the detection of microorganisms commonly associated to infertility. Most of seminal infections are frequently asymptomatic and go unnoticed, especially when they worsen the spermatic quality. Other rare infections as parasitic, mycotic and viral also alter the seminal quality.
Objective: To determine the infrequent infectious agents, bacterial and non-bacterial ones, that alter the seminal parameters.
Methods: In the databases Medline, PubMed and Google Scholar were consulted old initial studies published between the years 2004 and 2020. The full text version was obtained through free Access in PubMed, HINARI and other sources.
Development: In the reviewed literature are mentioned some etiological agents associated with oligozoospermia and astenozoospermia as Trichomonas vaginalis, Tripanosoma cruzy and Toxoplasma gondii, while hematospermia was related with Leishmania ssp., Schistosoma haematobium and cytomegalovirus. The dysfunction of the accessory glands and the seminal hyperviscosity were associated to viral infections by cytomegalovirus, herpes simplex, Epstein Barr and parasites as T. vaginalis, Leishmania spp and S. haematobium.
Conclusions: The percentage of idiopathic infertility can be reduced with the study of the infrequent infectious agents and their combination with the seminal parameters based in the pathogenesis of each microorganism. There is a need of studies in large scale to standardize the variables that determine the specific features and reference values which help to optimize the diagnosis, treatment and prevention of this infectious agents in male infertility.


REFERENCES

  1. Solomon M, Henkel R. Semen culture and the assessment of genitourinary tract infections. Indian J Urol. 2017. 33(3):188-93. DOI: https://doi.org/10.4103/iju.IJU_407_16

  2. Lozano Hernández JR. Male accessory glands and sperm function. En: Spermatozoa. Facts and perspectives. Intech Londres: Open; 2018; 101- 16. DOI: http://dx.doi.org/10.5772/intechopen.74321

  3. Lozano-Hernández R, Vivas-Acevedo G, Muñoz MG. Mycoplasmas y anticuerpos anti- Chlamydia en semen de hombres infértiles y su relación con la calidad seminal y los marcadores de glándulas sexuales accesorias masculinas. Invest Clin. 2012 [acceso: 12/06/2019]; 53(2):138-47. Disponible en: http://ve.scielo.org/scielo.php?script=sci_artte xt&pid=S0535-51332012000200003&lng=es

  4. Chemaitelly H, Weiss HA, Smolak A, Majed E, Abu-Raddad LJ. Epidemiology of Treponema pallidum, Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, and herpes simplex virus type 2 among female sex workers in the Middle East and North Africa: systematic review and meta-analytics. J Glob Health. 2019; 9(2):020408. DOI: https://doi.org/10.7189/jogh.09.020408

  5. Franco JVA, Turk T, Jung JH, Xiao YT, Iakhno S, Garrote V, et al. Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome: a Cochrane systematic review. BJU Int. 2019; 124(2):197-208. DOI: https://doi.org/10.1111/bju.14492

  6. Mashaly M, Masallat DT, Elkholy AA, Abdel I, Mostafa T. Seminal Corynebacterium strains in infertile men with and without leucocytospermia. Andrologia. 2015 [acceso: 16/06/2019]; 48:355-9. Disponible en: https://onlinelibrary.wiley.com/doi/abs/10.111 1/and.12457

  7. Kaur S, Prabha V. Infertility as a consequence of spermagglutinating Staphylococcus aureus colonization in genital tract of female mice. PLoSOne 2012; 7(12):e52325. DOI: https://doi.org/10.1371/journal.pone.0052325

  8. Lozano-Hernández R, Velasco J, Pacheco L, Sayago A, Peña J. Impacto de Staphylococcus epidermidis en el testículo murino. RSVM 2018 [acceso: 16/06/2019]; 38(1):10-14. Disponible en: https://www.researchgate.net/publication/328 073183_Impacto_de_Staphylococcus_epidermi dis_en_el_testiculo_murino/citation/download

  9. Guerrero-Hurtado LS, Puerta-Suárez J, Cardona-Maya WD. Papel de los espermatozoides en la transmisión de bacterias uropatógenas: Escherichia coli y Enterococcus faecalis. Clin Invest Ginecol Obstet. 2016; 45(1):2-6. DOI: https://doi.org/10.1016/j.gine.2016.03.003

  10. Belga S, Chen W, Low G, Cervera C. Xanthogranulomatous prostatitis presenting as Pseudomonas aeruginosa prostatic abscesses: An uncommon complication after kidney transplantation. ID Cases. 2019; 17:e00559. DOI: https://doi.org/10.1016/j.idcr.2019.e00559

  11. Massari F, Mollica V, Di Nunno V, Gatto L, Santoni M, Scarpelli M, et al. The Human Microbiota and Prostate Cancer: Friend or Foe? Cancers (Basel). 2019; 11(4):459. DOI: https://doi.org/10.3390/cancers11040459

  12. Thaper D, Rahi DK, Prabha V. Amelioration of sperm immobilization factor-induced infertility by bacterial antigenic determinants crossreacting with spermatozoa. Reprod Fertil Dev. 2019; 31(3):602-12. DOI: https://doi.org/doi 10.1071/RD18300

  13. Ubeda JL, Ausejo R, Dahmani Y, Falceto MV, Usan A, Malo C, et al. Adverse effects of members of the Enterobacteriaceae family on boar sperm quality. Theriogenology. 2013; 80(6):565-70. DOI: https://doi.org/10.1016/j.theriogenology.2013. 05.022

  14. Ricci S, De Giorgi S, Lazzeri E, Luddi A, Rossi S, Piomboni P, et al. Impact of asymptomatic genital tract infections on in vitro Fertilization (IVF) outcome. PLoS One. 2018 [acceso: 04/11/2019]; 13(11):e0207684. Disponible en: https://journals.plos.org/plosone/article?id=10. 1371/journal.pone.0207684

  15. Zuleta-González MC, Zapata-Salazar ME, Guerrero-Hurtado LS, Puerta-Suárez J, Cardona- Maya WD. Klebsiella pneumoniae and Streptococcus agalactiae: Passengers in the sperm travel. Arch Esp Urol. 2019; 72(9):939-47.

  16. Vilvanathan S, Kandasamy B, Jayachandran AL, Sathiyanarayanan S, Tanjore V, Krishnamurthy V, et al. Bacteriospermia and its impact on basic semen parameters among infertile men. Interdiscip Perspect Infect Dis. 2016; 2016:2614692. DOI: http://dx.doi.org/10.1155/2016/2614692

  17. Zhu XR, Li LH, Fan LX, Li BJ, Lan Y, Li F, et al. Semen quality and HIV RNA level in HIV/AIDS male patients after treated by highly active antiretroviral therapy. Zhonghua Nan KeXue. 2018; 24(5):414-8.

  18. Salam AP, Horby PW. The breadth of viruses in human semen. Emerg Infect Dis. 2017; 23(11):1922-24. DOI: https://doi.org/10.3201/eid2311.171049

  19. Du Plessis S, Agarwal A, Sabanegh E. Male infertility. New York: Springer; 2014, p. 134.

  20. Gheit T. Mucosal and cutaneous human papillomavirus infections and cancer biology. Front Oncol. 2019; 9:355. DOI: https://doi.org/10.3389/fonc.2019.00355

  21. Paz-Zulueta M, Fernández-Feito A, Amparán Ruiz M, Azofra Olave A, Martin Seco Y, Ojugas Zabala S, et al. Prevalencia de genotipos del virus del papiloma humano de alto riesgo no vacunables dentro del programa de detección precoz de cáncer de cérvix en Cantabria. Aten Primaria. 2016; 48(6):347-55. DOI: https://doi.org/10.1016/j.aprim.2015.07.006

  22. Lippold S, Braun B, Krüger F, Harms M, Müller JA, GroB R, et al. Natural Inhibitor of human cytomegalovirus in human seminal plasma. J Virol. 2019; 93(6):e01855-18. DOI: https://doi.org/10.1128/JVI.01855-18

  23. Alikhan MB, Tesic V, Taxy JB, Antic T. Cytomegalovirus Infection of Seminal Vesicles. Int J Surg Pathol. 2016; 24(8):720. DOI: https://doi.org/10.1177/1066896916657592

  24. Tang Q, Roan NR, Yamamura Y. Seminal plasma and semen amyloids enhance cytomegalovirus infection in cell culture. J Virol. 2013; 87(23):12583-91. DOI: https://doi.org/10.1128/JVI.02083-13

  25. Gianella S, Ginocchio CC, Daar ES, Dube MP, Morris SR. Genital Epstein Barr Virus is associated with higher prevalence and persistence of anal human papillomavirus in HIV-infected men on antiretroviral therapy. BMC Infect Dis. 2016; 16:24. DOI: https://doi.org/10.1186/s12879-016-1356-y

  26. Karamolahi S, Yazdi RS, Zangeneh M, Makiani MJ, Farhoodi B, Gilani MAS. Impact of hepatitis B virus and hepatitis C virus infection on sperm parameters of infertile men. Int J Reprod Biomed (Yazd). 2019; 17(8):551-6. DOI: https://doi.org/10.18502/ijrm.v17i8.4820

  27. Nicopoullos JDM, Almeida PA, Ramsay JWA, Gilling-Smith C. The effect of human immunodeficiency virus on sperm parameters and the outcome of intrauterine insemination following sperm washing. Hum Reprod. 2004; 19(10):2289-97. DOI: https://doi.org/10.1093/humrep/deh426.

  28. Uraki R, Hwang J, Ann K, Jurado K, Householder S, Yockey L, et al. Zika virus causes testicular atrophy. Sci Adv. 2017; 3(2):e1602899. DOI: https://doi.org/10.1126/sciadv.1602899

  29. Haby MM, Pinart M, Elias V, Reveiz L. Prevalence of asymptomatic Zika virus infection: a systematic review. Bull World Health Organ. 2018; 96(6):402-13. DOI: https://doi.org/10.2471/BLT.17.201541

  30. Capra G, Schillaci R, Bosco L, Roccheri MC, Perino A, Ragusa MA. HPV infection in semen: results from a new molecular approach. Epidemiol Infect. 2019; 147: e177. DOI: https://doi.org/10.1017/S0950268819000621

  31. Wang D, Li L, Xie Q, Hou Z, Yu X, Ma M, et al. Factors affecting sperm fertilizing capacity in men infected with HIV. J Med Virol. 2014; 86(9):1467-72. DOI: https://doi.org/10.1002/jmv.23991

  32. Jersovienė V, Gudlevicienė Z, Rimienė J, Butkauskas D. Human Papillomavirus and Infertility. Medicina (Kaunas). 2019; 55(7):377. DOI: https://doi.org/10.3390/medicina55070377

  33. Moghimi M, Zabihi-Mahmoodabadi S, Kheirkhah-Vakilabad A, Kargar Z. Significant Correlation between high-risk HPV DNA in semen and impairment of sperm quality in infertile men. Int J Fertil Steril. 2019; 12(4):306- 9. DOI: https://doi.org/10.22074/ijfs.2019.5421

  34. Dubaut J, Gurung S, Trammell M, Myers D, Reuter D, Preno A, et al. Semen parameters during zika virus infection in the olive baboon (Papio anubis). Fertil Steril. 2017; 108(3):e52- e53. DOI: https://doi.org/10.1016/j.fertnstert.2017.07.16 8

  35. Kang X, Xie Q, Zhou X, Li F, Huang J, Liu D, et al. Effects of hepatitis B virus S protein exposure on sperm membrane integrity and functions. PLoS ONE 2012; 7:e33471. DOI: https://doi.org/10.1371/journal.pone.0033471

  36. Lorusso F, Palmisano M, Chironna M, Vacca M, Masciandaro P, Bassi E, et al. Impact of chronic viral diseases on semen parameters. Andrologia. 2010; 42:121-6. DOI: https://doi.org/10.1111/j.1439- 0272.2009.00970.x

  37. La Vignera S, Condorelli RA, Vicari E, D'Agata R, Calogero AE. Sperm DNA damage in patients with chronic viral C hepatitis. Eur J Intern Med. 2012; 23:e19-e24. DOI: https://doi.org/10.1016/j.ejim.2011.08.011

  38. Shiadeh MN, Niyyati M, Fallahi S, Rostami A. Human parasitic protozoan infection to infertility: A systematic review. Parasitol Res. 2016; 115:469-47.

  39. Iqbal J, Al-Rashed J., Kehinde EO. Detection of Trichomonas vaginalis in prostate tissue and serostatus in patients with asymptomatic benign prostatic hyperplasia. BMC Infect Dis. 2016; 16:506. DOI: https://doi.org/10.1186/s12879- 016-1843-1

  40. Abdel-Naser MB, Wollina U, Lohan M, Zouboulis CC, Altenburg A. Schistosomiasis (Bilharziasis) ova: An incidental finding in testicular tissue of an obstructive azoospermic man. Andrología. 2018; 50(10):e13131. DOI: https://doi.org/10.1111/and.13131

  41. Tayra E, Ashmaig A, Shareef H, Bedawi S, Aradaib I. Association of Schistosoma mansoni with infertility in a Sudanese patient from schistosomiasis area of endemicity: A case report. Res J Med Sci. 2010; 4(3):125-7. DOI: https://doi.org/10.3923/rjmsci.2010.125.127

  42. Dalimi A, Abdoli A. Toxoplasma gondii an male reproduction impairment: a new aspect of toxoplasmosis. Jundishapur J Microbiol. 2013; 6:e7184. DOI: https://doi.org/10.5812/jjm.7184

  43. Wada YA, Oniye SJ, Rekwot PI, Okubanio OO. Testicular pathology, gonadal and epididymal sperm reserves of Yankasa rams infected with experimental Trypanosoma brucei brucei and Trypanosoma evansi. Vet World. 2016; 9(7):759- 65. DOI: https://doi.org/10.14202/vetworld.2016.759- 765

  44. Rodríguez O, Martínez E, Hernández, Aguilar R. Sperm morphological features associated with chronic Chagas diasease in the semen of experimentally infected dogs J Trop Med Hyg. 2014; 91(4):810-5. DOI: https://doi.org/10.4269/ajtmh.13-0207

  45. Castrillón-Duque EX, Puerta Suárez J, Cardona Maya WD. Yeast and fertility: Effects of in vitro activity of Candida spp. on sperm quality. J Reprod Infertil. 2018; 19(1):49-55.

  46. Demirci A, Bozlak N, Turkel S. Chronic prostatitis developing due to candida infection: A case diagnosed 20 years later and review of up-to-date literature. Urol Case Rep. 2018; 20:88-9. DOI: https://doi.org/10.1016/j.eucr.2018.07.014

  47. Shah SI, Bui H, Velasco N, Rungta S. Incidental finding of Cryptococcus on prostate biopsy for prostate adenocarcinoma following cardiac transplant: Case report and review of the literature. Am J Case Rep. 2017; 18:1171-80. DOI: https://doi.org/10.12659/AJCR.905528

  48. McBride JA, Gauthier GM, Klein BS. Clinical manifestations and treatment of blastomycosis. Clin Chest Med. 2017; 38(3):435-49. DOI: https://doi.org/doi:10.1016/j.ccm.2017.04.006

  49. Baud D, Vulliemoz N, Zapata MVM, Greub G, Vouga M, Stojanov M. Waddlia chondrophila and male infertility. Microorganisms. 2020; 8(1):136. DOI: https://doi.org/doi:10.3390/microorganisms80 10136

  50. Vivas-AG, Lozano J, Velasco J. Regulación inmuno-testicular y citocinas. Invest Clin. 2007 [acceso: 21/02/2019]; 48(1):107-21. Disponible en: http://ve.scielo.org/scielo.php?script=sci_arttext&pid=S0535-51332007000100011&lng=es




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

RCU. 2020;9